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The map label for this gene is htpG

Identifier: 50083587

GI number: 50083587

Start: 316092

End: 318014

Strand: Direct

Name: htpG

Synonym: ACIAD0316

Alternate gene names: 50083587

Gene position: 316092-318014 (Clockwise)

Preceding gene: 50083586

Following gene: 50083589

Centisome position: 8.78

GC content: 41.13

Gene sequence:

>1923_bases
ATGACTGAACAAACAGCAACACAGAATTATAGTTTTCAGGCGGAAGTTGCACAGCTTTTGCATCTTGTGACCCATTCATT
GTATTCCAATCCAGAAATTTTCCTGCGTGAATTGATTTCGAATGCTTCTGATGCCTGTGATAAATTACGTTTTGAAGGAA
TTAATCATCCTGAATATTATGAAGATGATGCCAACTTACGTGTTCGTGTGAGTTTAGATAAAGAAAACAAAACGATCACT
ATTTCAGATAATGGTATTGGTTTAAGTCAGCAAGAAGCGATTGATAATCTGGGAACCATTGCAAAATCGGGCACCAAAGA
CTTTATGTCGAAACTCACGGGTGACCAAAAATCAGATGCACAACTGATTGGTCAGTTTGGTGTTGGTTTTTATTCTGGAT
TTATTGTTGCGGATAAAATCACGGTAGAATCACGTCGTGCGGGTTTACCTGCAAATGATGGTGTGCGCTGGATTAGTGGC
GGTACAGGAGATTTTGAAGTACAACAAATCACCAAGGATTCACGTGGAACAAGCATCATTTTGCATTTACGCGATGATGC
ATTGGACTATCTGGATGCATGGAAAGTTAAACAGATTATCAATAAATACTCTGACCACATTAGCCTGCCTATTGAAATGC
AAAAAGAAGTCTGGCAGGAAGAAGAAGTCGCGGAAGGCGAAGAGCCAAAAGGCGGTCAGTATGTAAAAACAGACGAGTGG
GAAGTCATCAACTCGGCAAGTGCCTTATGGACACGCAGCAAAAATGAAATCAGTGAAGAGCAGTATATTGAGTTTTACAA
AAATTTGACTCACGACTTTGACGCTCCTTTAGCTTGGTCACATAACCGCGTAGAAGGCAATACCGAATACACCCAGTTAC
TTTATATTCCTGCCAAAGCATCGAGTGATATTTTCACCCGTGAAGCCAAAGCAGGTATTAAGCTGTATGTGAAGCGTGTG
TTTATTATGGATGATGCGGATAATCTGATTCCAAACTATTTGCGCTTTGTTAAAGGTGTCATTGACAGTGCAGACTTGCC
ACTCAATGTGAGCCGTGAACTTTTACAAGAGAGCCGTGATGTTAAAACCATTCGTGAAGGCAACACGCGCCGTGTATTGA
CTTTACTGGATGGTCTGGCCAAATCTGAAGATGAGAAAGATCAGGAAAAATTCAAGACTTTCTATCAAGAGTTTGGTTCT
GTACTCAAAGAAGGTTTAGGTGAAGATTTTACAAATCGTGAGCGTATTTTAAAATTATTGCGCTATGCGACATCAAATCA
GGACGAAATCTCGACCTCATTTGCCGATTATAAAGCACGTATGAAAGAAGGCCAAAAGGCCATCTATTATGTGAGTGCTG
ATAGTTTGGCTGCTGCCAAAAATTCGCCACAGCTTGAATTATTTAAGAAAAAAGGCATTGAAGTATTACTGATGTCTGAA
CGTGTAGACGAATGGGCAATGAACTTCGTACATGAGTTTGATGGTACACCTCTACAAAATGTGTCTAAAGGCGCGGTAGA
TTTGGGTGACCTGCAAGATGCCGAAGAAAAGAAAGCATTGGAACAGGCAGCAGAACAGTTCAAACCTGTGGTGGATAAAC
TCACAGATGCTTTAAAAGACAAAACCAAAGAAGTACGCGTGACTACACGTCTAGTAGACTCGCCAGCATGTTTGGTCACC
AGTGATGGTGAGTTGTCTCCTCAACTGATTCGTATGCTGAAACAGGCGGGTCAGGCTGTACCAGAGAGCAAGCCGATTTT
AGAAATCAATCCTGAACATCCTTTGGTACAAAAACTAGAAGGTTCGGCTCAGTTTGATGATTTGGCCAATGTCATTTTCG
ATCAAGCTGTGATTGCAGAAGGTGGTTTACCAGAAGATCCTGCGGCTTATGTCAAACGTATTAACAGCTTACTGTTAAAA
TAA

Upstream 100 bases:

>100_bases
TCAAAAAATCTTAAGCAGCCCCATTGAAAAAAGCATAGGGCACTCCAATACATATGGCATTACATAAAAAGATGTCGCTA
TAGATTTTAAGGAGTGCTTT

Downstream 100 bases:

>100_bases
AACATTTAAAAAACCGATCTAGTATCGGTTTTTTAAACACACTGTGGATAACTTCAAGGTTATCCATAGTTGTTGCTGTG
GTTAAAAGTTGGCTTCAAAC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MTEQTATQNYSFQAEVAQLLHLVTHSLYSNPEIFLRELISNASDACDKLRFEGINHPEYYEDDANLRVRVSLDKENKTIT
ISDNGIGLSQQEAIDNLGTIAKSGTKDFMSKLTGDQKSDAQLIGQFGVGFYSGFIVADKITVESRRAGLPANDGVRWISG
GTGDFEVQQITKDSRGTSIILHLRDDALDYLDAWKVKQIINKYSDHISLPIEMQKEVWQEEEVAEGEEPKGGQYVKTDEW
EVINSASALWTRSKNEISEEQYIEFYKNLTHDFDAPLAWSHNRVEGNTEYTQLLYIPAKASSDIFTREAKAGIKLYVKRV
FIMDDADNLIPNYLRFVKGVIDSADLPLNVSRELLQESRDVKTIREGNTRRVLTLLDGLAKSEDEKDQEKFKTFYQEFGS
VLKEGLGEDFTNRERILKLLRYATSNQDEISTSFADYKARMKEGQKAIYYVSADSLAAAKNSPQLELFKKKGIEVLLMSE
RVDEWAMNFVHEFDGTPLQNVSKGAVDLGDLQDAEEKKALEQAAEQFKPVVDKLTDALKDKTKEVRVTTRLVDSPACLVT
SDGELSPQLIRMLKQAGQAVPESKPILEINPEHPLVQKLEGSAQFDDLANVIFDQAVIAEGGLPEDPAAYVKRINSLLLK

Sequences:

>Translated_640_residues
MTEQTATQNYSFQAEVAQLLHLVTHSLYSNPEIFLRELISNASDACDKLRFEGINHPEYYEDDANLRVRVSLDKENKTIT
ISDNGIGLSQQEAIDNLGTIAKSGTKDFMSKLTGDQKSDAQLIGQFGVGFYSGFIVADKITVESRRAGLPANDGVRWISG
GTGDFEVQQITKDSRGTSIILHLRDDALDYLDAWKVKQIINKYSDHISLPIEMQKEVWQEEEVAEGEEPKGGQYVKTDEW
EVINSASALWTRSKNEISEEQYIEFYKNLTHDFDAPLAWSHNRVEGNTEYTQLLYIPAKASSDIFTREAKAGIKLYVKRV
FIMDDADNLIPNYLRFVKGVIDSADLPLNVSRELLQESRDVKTIREGNTRRVLTLLDGLAKSEDEKDQEKFKTFYQEFGS
VLKEGLGEDFTNRERILKLLRYATSNQDEISTSFADYKARMKEGQKAIYYVSADSLAAAKNSPQLELFKKKGIEVLLMSE
RVDEWAMNFVHEFDGTPLQNVSKGAVDLGDLQDAEEKKALEQAAEQFKPVVDKLTDALKDKTKEVRVTTRLVDSPACLVT
SDGELSPQLIRMLKQAGQAVPESKPILEINPEHPLVQKLEGSAQFDDLANVIFDQAVIAEGGLPEDPAAYVKRINSLLLK
>Mature_639_residues
TEQTATQNYSFQAEVAQLLHLVTHSLYSNPEIFLRELISNASDACDKLRFEGINHPEYYEDDANLRVRVSLDKENKTITI
SDNGIGLSQQEAIDNLGTIAKSGTKDFMSKLTGDQKSDAQLIGQFGVGFYSGFIVADKITVESRRAGLPANDGVRWISGG
TGDFEVQQITKDSRGTSIILHLRDDALDYLDAWKVKQIINKYSDHISLPIEMQKEVWQEEEVAEGEEPKGGQYVKTDEWE
VINSASALWTRSKNEISEEQYIEFYKNLTHDFDAPLAWSHNRVEGNTEYTQLLYIPAKASSDIFTREAKAGIKLYVKRVF
IMDDADNLIPNYLRFVKGVIDSADLPLNVSRELLQESRDVKTIREGNTRRVLTLLDGLAKSEDEKDQEKFKTFYQEFGSV
LKEGLGEDFTNRERILKLLRYATSNQDEISTSFADYKARMKEGQKAIYYVSADSLAAAKNSPQLELFKKKGIEVLLMSER
VDEWAMNFVHEFDGTPLQNVSKGAVDLGDLQDAEEKKALEQAAEQFKPVVDKLTDALKDKTKEVRVTTRLVDSPACLVTS
DGELSPQLIRMLKQAGQAVPESKPILEINPEHPLVQKLEGSAQFDDLANVIFDQAVIAEGGLPEDPAAYVKRINSLLLK

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=688, Percent_Identity=38.5174418604651, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI154146191, Length=707, Percent_Identity=37.0579915134371, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI153792590, Length=707, Percent_Identity=37.0579915134371, Blast_Score=430, Evalue=1e-120,
Organism=Homo sapiens, GI4507677, Length=687, Percent_Identity=36.3901018922853, Blast_Score=413, Evalue=1e-115,
Organism=Homo sapiens, GI155722983, Length=655, Percent_Identity=34.3511450381679, Blast_Score=360, Evalue=2e-99,
Organism=Escherichia coli, GI1786679, Length=633, Percent_Identity=54.6603475513428, Blast_Score=703, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=682, Percent_Identity=38.1231671554252, Blast_Score=456, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17542208, Length=684, Percent_Identity=36.4035087719298, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI115535205, Length=658, Percent_Identity=33.1306990881459, Blast_Score=308, Evalue=5e-84,
Organism=Caenorhabditis elegans, GI115535167, Length=445, Percent_Identity=35.0561797752809, Blast_Score=248, Evalue=5e-66,
Organism=Saccharomyces cerevisiae, GI6323840, Length=684, Percent_Identity=37.5730994152047, Blast_Score=438, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6325016, Length=690, Percent_Identity=36.6666666666667, Blast_Score=432, Evalue=1e-122,
Organism=Drosophila melanogaster, GI17647529, Length=691, Percent_Identity=37.9160636758321, Blast_Score=453, Evalue=1e-127,
Organism=Drosophila melanogaster, GI21357739, Length=685, Percent_Identity=37.956204379562, Blast_Score=427, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24586016, Length=658, Percent_Identity=34.1945288753799, Blast_Score=347, Evalue=1e-95,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_ACIAD (Q6FF82)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045097.1
- ProteinModelPortal:   Q6FF82
- STRING:   Q6FF82
- GeneID:   2878289
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0316
- NMPDR:   fig|62977.3.peg.730
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   Q6FF82
- ProtClustDB:   PRK05218
- BioCyc:   ASP62977:ACIAD0316-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71980; Mature: 71848

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQTATQNYSFQAEVAQLLHLVTHSLYSNPEIFLRELISNASDACDKLRFEGINHPEYY
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EDDANLRVRVSLDKENKTITISDNGIGLSQQEAIDNLGTIAKSGTKDFMSKLTGDQKSDA
CCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHH
QLIGQFGVGFYSGFIVADKITVESRRAGLPANDGVRWISGGTGDFEVQQITKDSRGTSII
HHHHHHHHHHHHCEEEEEEEEEHHHHCCCCCCCCEEEECCCCCCEEHHHHHCCCCCCEEE
LHLRDDALDYLDAWKVKQIINKYSDHISLPIEMQKEVWQEEEVAEGEEPKGGQYVKTDEW
EEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHCCCCCCCCCCEEECCCH
EVINSASALWTRSKNEISEEQYIEFYKNLTHDFDAPLAWSHNRVEGNTEYTQLLYIPAKA
HHHHCHHHHHHCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCC
SSDIFTREAKAGIKLYVKRVFIMDDADNLIPNYLRFVKGVIDSADLPLNVSRELLQESRD
CCCHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
VKTIREGNTRRVLTLLDGLAKSEDEKDQEKFKTFYQEFGSVLKEGLGEDFTNRERILKLL
HHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
RYATSNQDEISTSFADYKARMKEGQKAIYYVSADSLAAAKNSPQLELFKKKGIEVLLMSE
HHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHCCCCCCHHHHHHCCCEEEEEHH
RVDEWAMNFVHEFDGTPLQNVSKGAVDLGDLQDAEEKKALEQAAEQFKPVVDKLTDALKD
HHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTKEVRVTTRLVDSPACLVTSDGELSPQLIRMLKQAGQAVPESKPILEINPEHPLVQKLE
HHHHHHHHHHEECCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHC
GSAQFDDLANVIFDQAVIAEGGLPEDPAAYVKRINSLLLK
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEQTATQNYSFQAEVAQLLHLVTHSLYSNPEIFLRELISNASDACDKLRFEGINHPEYY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EDDANLRVRVSLDKENKTITISDNGIGLSQQEAIDNLGTIAKSGTKDFMSKLTGDQKSDA
CCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHH
QLIGQFGVGFYSGFIVADKITVESRRAGLPANDGVRWISGGTGDFEVQQITKDSRGTSII
HHHHHHHHHHHHCEEEEEEEEEHHHHCCCCCCCCEEEECCCCCCEEHHHHHCCCCCCEEE
LHLRDDALDYLDAWKVKQIINKYSDHISLPIEMQKEVWQEEEVAEGEEPKGGQYVKTDEW
EEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHCCCCCCCCCCEEECCCH
EVINSASALWTRSKNEISEEQYIEFYKNLTHDFDAPLAWSHNRVEGNTEYTQLLYIPAKA
HHHHCHHHHHHCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCC
SSDIFTREAKAGIKLYVKRVFIMDDADNLIPNYLRFVKGVIDSADLPLNVSRELLQESRD
CCCHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
VKTIREGNTRRVLTLLDGLAKSEDEKDQEKFKTFYQEFGSVLKEGLGEDFTNRERILKLL
HHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
RYATSNQDEISTSFADYKARMKEGQKAIYYVSADSLAAAKNSPQLELFKKKGIEVLLMSE
HHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHCCCCCCHHHHHHCCCEEEEEHH
RVDEWAMNFVHEFDGTPLQNVSKGAVDLGDLQDAEEKKALEQAAEQFKPVVDKLTDALKD
HHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTKEVRVTTRLVDSPACLVTSDGELSPQLIRMLKQAGQAVPESKPILEINPEHPLVQKLE
HHHHHHHHHHEECCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHC
GSAQFDDLANVIFDQAVIAEGGLPEDPAAYVKRINSLLLK
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA