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The map label for this gene is ephD [H]

Identifier: 50083583

GI number: 50083583

Start: 312017

End: 312958

Strand: Direct

Name: ephD [H]

Synonym: ACIAD0312

Alternate gene names: 50083583

Gene position: 312017-312958 (Clockwise)

Preceding gene: 50083581

Following gene: 50083584

Centisome position: 8.67

GC content: 40.98

Gene sequence:

>942_bases
ATGGCATTGATGGCAATGCCCAATCTGACTAACAATATGGTCAATCAAAATAAAAAGGAAACGACAATGCATCCACAGAT
TCATACCGTCCAGACCTCAGATCATCAATTCTTATGTGCGAAAACTTGGGGAAAACCTGAACTTCCAGCATTAGTTTTAG
TGCATGGCTATCCAGATAACCAAGAAGTGTGGGAGCCGATCATTCACGAGTTAATCAACGAGTTTTATATCGTCACGTAT
GATGTTCGAGGTGCGGGTGAGTCTAGTATTCCAAAACATATCCGTGATTATCGTCTTGAACGCTTATCCTTAGATCTGGA
AGCAGTGGTTAATCAGTTATTGGGTCATCGTCCATTTCATCTGGCTGCACATGATTGGGGATCCATCCAAACATGGGAGT
CAGTGACAGAACCTAGATTCAAAGATCGCATACTTTCTTATACGACTATTTCTGGCCCTTGTCTGGATCATGCTGCGATG
TTGCTAGGTGATGAAATCAAACAAAATCCAGTAGGATTTTTGAAAAAACTGTCTAAATCATGGTATATCGCAGCATTTCA
TTTACCGTTACTTGCACCTACGGTGTGGCAATTTCTTACTGCAAAACAATGGGCCAAAGTCTTAAGTGGTCTTGAAAAAA
AATCAAATTTACCACTTAACCACAATATTGCAAAAGATGGAAAATATGGCATCAATTTGTATCGTGCCAATTTTATCCCT
GCGCTGACCAAACCGCGTGAGCGTTATGCTCAGTGCCCTGTACAGGCCGTTGTTTTGACACGTGATGCTTTTGTCAGTCC
TGATTATATTTTAAAGGAAATGCCAAAGTGGGTAGATCAATTTGAATACGTAGAACTTGATGCAAACCATTGGGCTATCC
TGAGTCAGCCACAAACGATTGCCAAGTATATTGCAGGTTTTGCACAACGACATCCTGTATAG

Upstream 100 bases:

>100_bases
ATTTGGACACCATGGGTATGGTTTGAAGTTGTTTTAAAATATTCATATCGGTCAATTGTTTTTATATCGTGATTATTCAT
ACTAGATAACTATCACTAAT

Downstream 100 bases:

>100_bases
GTTATCTTGGAATCATCAGGAGACGACATTGAAGTGGTTTGACTAAATAGTGAATTATCCAGAATCATGAAAGTGAATCT
GCTAAAATATCGCCCTTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MALMAMPNLTNNMVNQNKKETTMHPQIHTVQTSDHQFLCAKTWGKPELPALVLVHGYPDNQEVWEPIIHELINEFYIVTY
DVRGAGESSIPKHIRDYRLERLSLDLEAVVNQLLGHRPFHLAAHDWGSIQTWESVTEPRFKDRILSYTTISGPCLDHAAM
LLGDEIKQNPVGFLKKLSKSWYIAAFHLPLLAPTVWQFLTAKQWAKVLSGLEKKSNLPLNHNIAKDGKYGINLYRANFIP
ALTKPRERYAQCPVQAVVLTRDAFVSPDYILKEMPKWVDQFEYVELDANHWAILSQPQTIAKYIAGFAQRHPV

Sequences:

>Translated_313_residues
MALMAMPNLTNNMVNQNKKETTMHPQIHTVQTSDHQFLCAKTWGKPELPALVLVHGYPDNQEVWEPIIHELINEFYIVTY
DVRGAGESSIPKHIRDYRLERLSLDLEAVVNQLLGHRPFHLAAHDWGSIQTWESVTEPRFKDRILSYTTISGPCLDHAAM
LLGDEIKQNPVGFLKKLSKSWYIAAFHLPLLAPTVWQFLTAKQWAKVLSGLEKKSNLPLNHNIAKDGKYGINLYRANFIP
ALTKPRERYAQCPVQAVVLTRDAFVSPDYILKEMPKWVDQFEYVELDANHWAILSQPQTIAKYIAGFAQRHPV
>Mature_312_residues
ALMAMPNLTNNMVNQNKKETTMHPQIHTVQTSDHQFLCAKTWGKPELPALVLVHGYPDNQEVWEPIIHELINEFYIVTYD
VRGAGESSIPKHIRDYRLERLSLDLEAVVNQLLGHRPFHLAAHDWGSIQTWESVTEPRFKDRILSYTTISGPCLDHAAML
LGDEIKQNPVGFLKKLSKSWYIAAFHLPLLAPTVWQFLTAKQWAKVLSGLEKKSNLPLNHNIAKDGKYGINLYRANFIPA
LTKPRERYAQCPVQAVVLTRDAFVSPDYILKEMPKWVDQFEYVELDANHWAILSQPQTIAKYIAGFAQRHPV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=281, Percent_Identity=24.5551601423488, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI13376164, Length=281, Percent_Identity=24.5551601423488, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 35871; Mature: 35740

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALMAMPNLTNNMVNQNKKETTMHPQIHTVQTSDHQFLCAKTWGKPELPALVLVHGYPDN
CCEEECCCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCC
QEVWEPIIHELINEFYIVTYDVRGAGESSIPKHIRDYRLERLSLDLEAVVNQLLGHRPFH
HHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEE
LAAHDWGSIQTWESVTEPRFKDRILSYTTISGPCLDHAAMLLGDEIKQNPVGFLKKLSKS
EECCCCCCCCCHHHHCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHCCC
WYIAAFHLPLLAPTVWQFLTAKQWAKVLSGLEKKSNLPLNHNIAKDGKYGINLYRANFIP
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCC
ALTKPRERYAQCPVQAVVLTRDAFVSPDYILKEMPKWVDQFEYVELDANHWAILSQPQTI
CCCCCHHHHHHCCCEEEEEEHHHCCCHHHHHHHHHHHHCCCEEEEECCCCEEEECCCHHH
AKYIAGFAQRHPV
HHHHHHHHHCCCC
>Mature Secondary Structure 
ALMAMPNLTNNMVNQNKKETTMHPQIHTVQTSDHQFLCAKTWGKPELPALVLVHGYPDN
CEEECCCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCC
QEVWEPIIHELINEFYIVTYDVRGAGESSIPKHIRDYRLERLSLDLEAVVNQLLGHRPFH
HHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEE
LAAHDWGSIQTWESVTEPRFKDRILSYTTISGPCLDHAAMLLGDEIKQNPVGFLKKLSKS
EECCCCCCCCCHHHHCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHCCC
WYIAAFHLPLLAPTVWQFLTAKQWAKVLSGLEKKSNLPLNHNIAKDGKYGINLYRANFIP
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCC
ALTKPRERYAQCPVQAVVLTRDAFVSPDYILKEMPKWVDQFEYVELDANHWAILSQPQTI
CCCCCHHHHHHCCCEEEEEEHHHCCCHHHHHHHHHHHHCCCEEEEECCCCEEEECCCHHH
AKYIAGFAQRHPV
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]