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The map label for this gene is ftsW [H]

Identifier: 50083548

GI number: 50083548

Start: 271466

End: 272665

Strand: Direct

Name: ftsW [H]

Synonym: ACIAD0271

Alternate gene names: 50083548

Gene position: 271466-272665 (Clockwise)

Preceding gene: 50083547

Following gene: 50083554

Centisome position: 7.54

GC content: 45.58

Gene sequence:

>1200_bases
GTGATGGCTGGCTTTGCTCAGACAACCATAACCAAGATTAATCAGTTTTATGAACGCTGGATGCCACGCCTGCCCGCAGA
AATGACAGCCCGAAATGTCTTGGTTTTCTGTGTCGTATGTTTACTCTGTATTGGTTCAGTCATGGTCGCTTCGGCGTCTA
TGCCGTATGCCGAGTATATGCATGAAAATCCGTTTCATTACGTGGTGCGACATGCAATTTCAATTGCGACCGCGGCAATC
GTGGCTTATCTGGTGTATAAGGTTCCGTTGAATGTCTGGTTTAAAAATACATTCTCATTTTGGTTGATCACCATTTTGCT
CTTGCTTGCAGTATTGGTCATTGGAACAGAAGTGAACGGTTCACGGCGCTGGATTCGTCTGGCTGGATTTACCTTGCAGC
CGACAGAAGTTGCCAAAGTGATGATGGCGATTTTTACTGCCGACTATGTTGTACGGCGTGCCAAAGAAGTACGGACACAC
TGGAAAGGGCTGGTACGGTTGAGTGGTGTGATGGCGATTACTGTCGGGCTGATCATTGCAGAACCAGATTTAGGTGCTAC
TGTGGTAATCGTCCTGATGATGGTCGGGATCTTTTTTCTGGCGGGTGCACCACCCACTCAATTTGCGATTATGTTAGGTG
CAGTGGTGATGGGAATTGGTTTCCTGATCCTGTTTGAGCCTTATCGTTTGGCACGGGCAATGTCTTTCACCAATCCATGG
GCAGATCCGTTAGGCACAGGTTATCAGCTTTCCAATGCCCTGATGGCCTTTGGGCGAGGTGAATGGTTTGGCACAGGTTT
AGGTCACAGTGTTCAAAAACTCTCGTATTTACCCGAAGCGCATACCGACTTTATGTTGGCTGTATTGGGTGAGGAGTTTG
GCTTCGTCGGTATTTCGATTGTTATCGGTTTATCGTTTATTATGCTGGCTTGTTGTATCAAGATTGGACATCGTGCCTTA
AAGCATAATTTCTTGCGTGCAGGTTATCTGGCGTACGGTATTAGTATCATTTTTCTGCTCCAGATTATTGTAAATGCAGG
TATGAACATGGGGCTCATGCCAACCAAAGGTTTGACTTTGCCATTCATTAGTTATGGTGGAACATCATTAATGATGTGTG
CAGCGATGATTAGTTTGATTTTGCGAATAGATGCCTCGACTCAGGAGATTAATCCTGATCGTGAAGAATCCAACTTCTAA

Upstream 100 bases:

>100_bases
ATGTGCAAGTTTTGATATGTTTAAAGGTTATCCAGATCGGGGACATCAATTTGTTGCCTGTGTGGATGCGCTGGTTTAAA
ACAAAAATGAGAAGGAAAAT

Downstream 100 bases:

>100_bases
AAAATCAGTATAAAAAAGCCGCCCATTGTGAATTGCATCCTGAAAGTTGGACACTTTTAGTCTAATTTGAAGGGTGCTTT
TCTATGGCAAGGTACTAGAG

Product: cell division protein, stabililzes FtsZ ring

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MMAGFAQTTITKINQFYERWMPRLPAEMTARNVLVFCVVCLLCIGSVMVASASMPYAEYMHENPFHYVVRHAISIATAAI
VAYLVYKVPLNVWFKNTFSFWLITILLLLAVLVIGTEVNGSRRWIRLAGFTLQPTEVAKVMMAIFTADYVVRRAKEVRTH
WKGLVRLSGVMAITVGLIIAEPDLGATVVIVLMMVGIFFLAGAPPTQFAIMLGAVVMGIGFLILFEPYRLARAMSFTNPW
ADPLGTGYQLSNALMAFGRGEWFGTGLGHSVQKLSYLPEAHTDFMLAVLGEEFGFVGISIVIGLSFIMLACCIKIGHRAL
KHNFLRAGYLAYGISIIFLLQIIVNAGMNMGLMPTKGLTLPFISYGGTSLMMCAAMISLILRIDASTQEINPDREESNF

Sequences:

>Translated_399_residues
MMAGFAQTTITKINQFYERWMPRLPAEMTARNVLVFCVVCLLCIGSVMVASASMPYAEYMHENPFHYVVRHAISIATAAI
VAYLVYKVPLNVWFKNTFSFWLITILLLLAVLVIGTEVNGSRRWIRLAGFTLQPTEVAKVMMAIFTADYVVRRAKEVRTH
WKGLVRLSGVMAITVGLIIAEPDLGATVVIVLMMVGIFFLAGAPPTQFAIMLGAVVMGIGFLILFEPYRLARAMSFTNPW
ADPLGTGYQLSNALMAFGRGEWFGTGLGHSVQKLSYLPEAHTDFMLAVLGEEFGFVGISIVIGLSFIMLACCIKIGHRAL
KHNFLRAGYLAYGISIIFLLQIIVNAGMNMGLMPTKGLTLPFISYGGTSLMMCAAMISLILRIDASTQEINPDREESNF
>Mature_399_residues
MMAGFAQTTITKINQFYERWMPRLPAEMTARNVLVFCVVCLLCIGSVMVASASMPYAEYMHENPFHYVVRHAISIATAAI
VAYLVYKVPLNVWFKNTFSFWLITILLLLAVLVIGTEVNGSRRWIRLAGFTLQPTEVAKVMMAIFTADYVVRRAKEVRTH
WKGLVRLSGVMAITVGLIIAEPDLGATVVIVLMMVGIFFLAGAPPTQFAIMLGAVVMGIGFLILFEPYRLARAMSFTNPW
ADPLGTGYQLSNALMAFGRGEWFGTGLGHSVQKLSYLPEAHTDFMLAVLGEEFGFVGISIVIGLSFIMLACCIKIGHRAL
KHNFLRAGYLAYGISIIFLLQIIVNAGMNMGLMPTKGLTLPFISYGGTSLMMCAAMISLILRIDASTQEINPDREESNF

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=357, Percent_Identity=42.5770308123249, Blast_Score=300, Evalue=8e-83,
Organism=Escherichia coli, GI1786853, Length=325, Percent_Identity=30.7692307692308, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44028; Mature: 44028

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MMAGFAQTTITKINQFYERWMPRLPAEMTARNVLVFCVVCLLCIGSVMVASASMPYAEYM
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
HENPFHYVVRHAISIATAAIVAYLVYKVPLNVWFKNTFSFWLITILLLLAVLVIGTEVNG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SRRWIRLAGFTLQPTEVAKVMMAIFTADYVVRRAKEVRTHWKGLVRLSGVMAITVGLIIA
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
EPDLGATVVIVLMMVGIFFLAGAPPTQFAIMLGAVVMGIGFLILFEPYRLARAMSFTNPW
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ADPLGTGYQLSNALMAFGRGEWFGTGLGHSVQKLSYLPEAHTDFMLAVLGEEFGFVGISI
CCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHH
VIGLSFIMLACCIKIGHRALKHNFLRAGYLAYGISIIFLLQIIVNAGMNMGLMPTKGLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PFISYGGTSLMMCAAMISLILRIDASTQEINPDREESNF
CCHHCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]