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The map label for this gene is pbpG [H]

Identifier: 50083539

GI number: 50083539

Start: 261717

End: 262775

Strand: Direct

Name: pbpG [H]

Synonym: ACIAD0262

Alternate gene names: 50083539

Gene position: 261717-262775 (Clockwise)

Preceding gene: 50083535

Following gene: 50083544

Centisome position: 7.27

GC content: 44.1

Gene sequence:

>1059_bases
GTGAAAAATGCCAAAAAATCTCTAAAACATGTATTAAGCATGTCGATTTTATTAGGTTTGAGTTCAACAAGCTTTGCAGA
ACTCATTGTGAATCCATCTTCAGGGAACGCTGCTGGGTCTGCTTCCTTAACATGGTCATCTGATGATGCAAACCAGTTGT
TAAACTCGGATCGTACGATTGATACTGTGCGAAGCCCGCAAGGTTCTACCTCAGTAACCACCACTGTCCGTAATGCAGCG
CCACCATCATCTGCTTCATCGTCATCACCTGCCTATGTGATTCGGGATACGACAAACTATGCTGCACAGCCGTCCGTGAA
TGCCCGTGCTGCACTGGTGATGGATGCCCAGACGGGTGAGGTACTGTACAGTAAAAATACCAATACATCTATGCCCATTG
CTTCATTAACCAAATTAATGACAGCGGTAGTCACATCTGATGCACGTCTTGATATGTCAGAAGAAATTACCTTAGAGCAA
ATTGATTTTGCTGGGGCAGGCGGTAAAAACTCAAGTTCTACATTGCGCGTGGGCGACAAGATGAATCGTGCAGAAGTACT
TTTGTTTGCATTGATGAAATCTGAAAATCCTGCTGCTGCTGCGTTGGCACGTACTTATCCTGGCGGTCGTCCTGCATTTG
TTGCTGCCATGAATGCGAAAGCGCGTCAGTTGGGTATGACATCTACTCATTATGTAGAGTCATCAGGGCTTGATCCGCAC
AATGTATCTTCAGCTCGCGATCTTGGTATTTTGGTGAGTGCGGCGTCTCAATATGGTTTGATCCGTCAGTTCTCGACCAC
ACCAAGTTATGATTTCAATTTAGGTTATCGTGTTTTAAAGTCAAACAATACCAATGCATTGGTACGTAATGGCGGTTGGA
ATATCAATTTATCCAAAACGGGTTATATTAATGAAGCAGGTCGCTGTGTTGTCATGCATACCACTGTAAACTCACGTCCT
GCTGTTGTGGTTCTGTTGGGTGCAAGTTCGACACAGGCACGTAATAATGATGCCACTAATCTTTTAAACTGGTTAGCGCA
ACAACCAAAACGAATTTAA

Upstream 100 bases:

>100_bases
GCAAAAATGTCTGACATTGCCATCATGCTTTATGCTCAAATGTAAGGCATAATAGTGGTAATAAGCAAATTTGTGTTTAC
CCTGAGTTGAGTAATTTGCC

Downstream 100 bases:

>100_bases
GACGATCTACAATATCAAGTTAGATGTCATAAAAATCTAGATATAAAAAAACCAGTTGCAAGCAACTGGTTTTTTTAATG
GGAAAATTAATTCTTACATA

Product: D-alanyl-D-alanine endopeptidase, penicillin-binding protein 7 and penicillin-binding protein 8

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 5; PBP-5 [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKNAKKSLKHVLSMSILLGLSSTSFAELIVNPSSGNAAGSASLTWSSDDANQLLNSDRTIDTVRSPQGSTSVTTTVRNAA
PPSSASSSSPAYVIRDTTNYAAQPSVNARAALVMDAQTGEVLYSKNTNTSMPIASLTKLMTAVVTSDARLDMSEEITLEQ
IDFAGAGGKNSSSTLRVGDKMNRAEVLLFALMKSENPAAAALARTYPGGRPAFVAAMNAKARQLGMTSTHYVESSGLDPH
NVSSARDLGILVSAASQYGLIRQFSTTPSYDFNLGYRVLKSNNTNALVRNGGWNINLSKTGYINEAGRCVVMHTTVNSRP
AVVVLLGASSTQARNNDATNLLNWLAQQPKRI

Sequences:

>Translated_352_residues
MKNAKKSLKHVLSMSILLGLSSTSFAELIVNPSSGNAAGSASLTWSSDDANQLLNSDRTIDTVRSPQGSTSVTTTVRNAA
PPSSASSSSPAYVIRDTTNYAAQPSVNARAALVMDAQTGEVLYSKNTNTSMPIASLTKLMTAVVTSDARLDMSEEITLEQ
IDFAGAGGKNSSSTLRVGDKMNRAEVLLFALMKSENPAAAALARTYPGGRPAFVAAMNAKARQLGMTSTHYVESSGLDPH
NVSSARDLGILVSAASQYGLIRQFSTTPSYDFNLGYRVLKSNNTNALVRNGGWNINLSKTGYINEAGRCVVMHTTVNSRP
AVVVLLGASSTQARNNDATNLLNWLAQQPKRI
>Mature_352_residues
MKNAKKSLKHVLSMSILLGLSSTSFAELIVNPSSGNAAGSASLTWSSDDANQLLNSDRTIDTVRSPQGSTSVTTTVRNAA
PPSSASSSSPAYVIRDTTNYAAQPSVNARAALVMDAQTGEVLYSKNTNTSMPIASLTKLMTAVVTSDARLDMSEEITLEQ
IDFAGAGGKNSSSTLRVGDKMNRAEVLLFALMKSENPAAAALARTYPGGRPAFVAAMNAKARQLGMTSTHYVESSGLDPH
NVSSARDLGILVSAASQYGLIRQFSTTPSYDFNLGYRVLKSNNTNALVRNGGWNINLSKTGYINEAGRCVVMHTTVNSRP
AVVVLLGASSTQARNNDATNLLNWLAQQPKRI

Specific function: Cell wall formation [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=254, Percent_Identity=43.3070866141732, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1787062, Length=260, Percent_Identity=30.3846153846154, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI87082022, Length=257, Percent_Identity=31.5175097276265, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786851, Length=254, Percent_Identity=27.1653543307087, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 37270; Mature: 37270

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNAKKSLKHVLSMSILLGLSSTSFAELIVNPSSGNAAGSASLTWSSDDANQLLNSDRTI
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHCCCCCE
DTVRSPQGSTSVTTTVRNAAPPSSASSSSPAYVIRDTTNYAAQPSVNARAALVMDAQTGE
EHHCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCC
VLYSKNTNTSMPIASLTKLMTAVVTSDARLDMSEEITLEQIDFAGAGGKNSSSTLRVGDK
EEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCC
MNRAEVLLFALMKSENPAAAALARTYPGGRPAFVAAMNAKARQLGMTSTHYVESSGLDPH
CCHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCHHHHCCCCCCEEEECCCCCCC
NVSSARDLGILVSAASQYGLIRQFSTTPSYDFNLGYRVLKSNNTNALVRNGGWNINLSKT
CCCCHHHHEEEEECHHHCCEEEEECCCCCCCCCCCEEEEECCCCCEEEECCCEEEEECCC
GYINEAGRCVVMHTTVNSRPAVVVLLGASSTQARNNDATNLLNWLAQQPKRI
CCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKNAKKSLKHVLSMSILLGLSSTSFAELIVNPSSGNAAGSASLTWSSDDANQLLNSDRTI
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHCCCCCE
DTVRSPQGSTSVTTTVRNAAPPSSASSSSPAYVIRDTTNYAAQPSVNARAALVMDAQTGE
EHHCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCC
VLYSKNTNTSMPIASLTKLMTAVVTSDARLDMSEEITLEQIDFAGAGGKNSSSTLRVGDK
EEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCC
MNRAEVLLFALMKSENPAAAALARTYPGGRPAFVAAMNAKARQLGMTSTHYVESSGLDPH
CCHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCHHHHCCCCCCEEEECCCCCCC
NVSSARDLGILVSAASQYGLIRQFSTTPSYDFNLGYRVLKSNNTNALVRNGGWNINLSKT
CCCCHHHHEEEEECHHHCCEEEEECCCCCCCCCCCEEEEECCCCCEEEECCCEEEEECCC
GYINEAGRCVVMHTTVNSRPAVVVLLGASSTQARNNDATNLLNWLAQQPKRI
CCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]