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The map label for this gene is prc [C]

Identifier: 50083535

GI number: 50083535

Start: 256653

End: 257834

Strand: Direct

Name: prc [C]

Synonym: ACIAD0257

Alternate gene names: 50083535

Gene position: 256653-257834 (Clockwise)

Preceding gene: 50083534

Following gene: 50083539

Centisome position: 7.13

GC content: 42.22

Gene sequence:

>1182_bases
ATGGCTCAACGCTTCAATTATCGCGTTTTTTTAACAAGTGTGTTGATGTGTTTGAGTCCGCTTTCATTTGCTGCCCCTCT
GATTCAACCTTCAAGTAATGTTGATGAAGATGGGCATGAGCTACATTCTGCTGAGGTACCAGTCGAATCCATTCAGCAGT
TTGTTCAGATTTACAATCTGGTCAAAGACAACTATGTGGAAGCTAAATCGGATGATGCCTTGTTCCAGCAAGCGATCAAA
GGTCTGGTCAGCGGTTTAGATCGTTATTCTCGCTATTTGTCTCCAGAAGATTATAAGCAATTGGTACAATATACCGAAGG
CGATTTGGCATCTGTCGATTTTGCTTTGGTTTACGATGCACGAATTCATCAGTGGGTGGTCCGTGATCTTAAAGAAGGTG
CAGATTCCTACAAGTTAGGTCTTAGAAATGGTCAGAATGTTCTTAAGATTGATGGACAAGATCTCCAAACGCTCAATCAT
GATCAGGTGCATACCCTGCTTTATGGCTCCATTGGTACGCCCATACAAATTCAGACGGCTGAAATGCCAGTATCTCAAAC
CCTGATCCGAAATAAAAAAATAGAGGCGGATGTTCAGCCAATTCTTTTGCATAACCAAGTGCTGGTTTTAAAAGTTAAAG
TCTTTCAGCAGGATACAGCTAACGAAATTAAGCGTTTGTTAGAAGAATACGGCTCGCCACGTTTGAAGGCTGTCATTATT
GATCTGCGTAATAATCCGGGTGGACTTCTTTCTGCCGCAGTTGAATCTGCTGATTTATTCTTGAATCAAGGAATTATTGT
TTCAACCAAAAGTCGTTCGGAAGGTAATCAACAATTTCAGGCCTTACCAAGCAGTGAATTTTTGCGTTTGAAGATGGGTA
TCTTGATTAATCACCGTTCAGCATCTGCTGCCGAGGTATTTACCGCTGCCATGAAAGATCATCAGCGTGCCTGGGTGATT
GGCGAAAAAAGTTATGGCAAAGGCGTCGTGCAGAAACTATTTCCATTGCCAGATGGTTCAGCTTTGCAAATGACGGTATC
GCATTATTACACACCAGATGGCAGCATGATTGAAGGTAAAGGGATTCAGCCGAACCAGCGTTATCCTTTACCTGCCGACA
TGAAAGATGAGACTTATTTGGAAAATGTAGCAGATCTATTGCTTAAACAGCCCAAATCCTGA

Upstream 100 bases:

>100_bases
GCTGATGTGGCGCCAACATTACTCAATTTGATGCAACTTCCTGTACCTGCAGAAATGCAGGGACGTAATTTAATTACTCT
CTCTTCATAAAGGTGACTGC

Downstream 100 bases:

>100_bases
TTTAGCCATCATCAGTATCAAGCCCAAATTTTTTCAGACGATAGCGAAGAGAGCGAAAACTCATTCCTAATTTTTTTGCG
GCTAAAGTACGATTCCAGTG

Product: periplasmic carboxyl-terminal protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MAQRFNYRVFLTSVLMCLSPLSFAAPLIQPSSNVDEDGHELHSAEVPVESIQQFVQIYNLVKDNYVEAKSDDALFQQAIK
GLVSGLDRYSRYLSPEDYKQLVQYTEGDLASVDFALVYDARIHQWVVRDLKEGADSYKLGLRNGQNVLKIDGQDLQTLNH
DQVHTLLYGSIGTPIQIQTAEMPVSQTLIRNKKIEADVQPILLHNQVLVLKVKVFQQDTANEIKRLLEEYGSPRLKAVII
DLRNNPGGLLSAAVESADLFLNQGIIVSTKSRSEGNQQFQALPSSEFLRLKMGILINHRSASAAEVFTAAMKDHQRAWVI
GEKSYGKGVVQKLFPLPDGSALQMTVSHYYTPDGSMIEGKGIQPNQRYPLPADMKDETYLENVADLLLKQPKS

Sequences:

>Translated_393_residues
MAQRFNYRVFLTSVLMCLSPLSFAAPLIQPSSNVDEDGHELHSAEVPVESIQQFVQIYNLVKDNYVEAKSDDALFQQAIK
GLVSGLDRYSRYLSPEDYKQLVQYTEGDLASVDFALVYDARIHQWVVRDLKEGADSYKLGLRNGQNVLKIDGQDLQTLNH
DQVHTLLYGSIGTPIQIQTAEMPVSQTLIRNKKIEADVQPILLHNQVLVLKVKVFQQDTANEIKRLLEEYGSPRLKAVII
DLRNNPGGLLSAAVESADLFLNQGIIVSTKSRSEGNQQFQALPSSEFLRLKMGILINHRSASAAEVFTAAMKDHQRAWVI
GEKSYGKGVVQKLFPLPDGSALQMTVSHYYTPDGSMIEGKGIQPNQRYPLPADMKDETYLENVADLLLKQPKS
>Mature_392_residues
AQRFNYRVFLTSVLMCLSPLSFAAPLIQPSSNVDEDGHELHSAEVPVESIQQFVQIYNLVKDNYVEAKSDDALFQQAIKG
LVSGLDRYSRYLSPEDYKQLVQYTEGDLASVDFALVYDARIHQWVVRDLKEGADSYKLGLRNGQNVLKIDGQDLQTLNHD
QVHTLLYGSIGTPIQIQTAEMPVSQTLIRNKKIEADVQPILLHNQVLVLKVKVFQQDTANEIKRLLEEYGSPRLKAVIID
LRNNPGGLLSAAVESADLFLNQGIIVSTKSRSEGNQQFQALPSSEFLRLKMGILINHRSASAAEVFTAAMKDHQRAWVIG
EKSYGKGVVQKLFPLPDGSALQMTVSHYYTPDGSMIEGKGIQPNQRYPLPADMKDETYLENVADLLLKQPKS

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=344, Percent_Identity=25.2906976744186, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 43961; Mature: 43829

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRFNYRVFLTSVLMCLSPLSFAAPLIQPSSNVDEDGHELHSAEVPVESIQQFVQIYNL
CCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHH
VKDNYVEAKSDDALFQQAIKGLVSGLDRYSRYLSPEDYKQLVQYTEGDLASVDFALVYDA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHCEEEEEEHH
RIHQWVVRDLKEGADSYKLGLRNGQNVLKIDGQDLQTLNHDQVHTLLYGSIGTPIQIQTA
HHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCHHHHCCCCHHHEEEECCCCCCEEEEEC
EMPVSQTLIRNKKIEADVQPILLHNQVLVLKVKVFQQDTANEIKRLLEEYGSPRLKAVII
CCCHHHHHHHCCCCCCCCCEEEECCCEEEEEEEHHHCCCHHHHHHHHHHHCCCCEEEEEE
DLRNNPGGLLSAAVESADLFLNQGIIVSTKSRSEGNQQFQALPSSEFLRLKMGILINHRS
EECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHCCCCHHHHEEEEEEEEECCC
ASAAEVFTAAMKDHQRAWVIGEKSYGKGVVQKLFPLPDGSALQMTVSHYYTPDGSMIEGK
CHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCCCEEEEEEEEEECCCCCEEECC
GIQPNQRYPLPADMKDETYLENVADLLLKQPKS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AQRFNYRVFLTSVLMCLSPLSFAAPLIQPSSNVDEDGHELHSAEVPVESIQQFVQIYNL
CCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHH
VKDNYVEAKSDDALFQQAIKGLVSGLDRYSRYLSPEDYKQLVQYTEGDLASVDFALVYDA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHCEEEEEEHH
RIHQWVVRDLKEGADSYKLGLRNGQNVLKIDGQDLQTLNHDQVHTLLYGSIGTPIQIQTA
HHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCHHHHCCCCHHHEEEECCCCCCEEEEEC
EMPVSQTLIRNKKIEADVQPILLHNQVLVLKVKVFQQDTANEIKRLLEEYGSPRLKAVII
CCCHHHHHHHCCCCCCCCCEEEECCCEEEEEEEHHHCCCHHHHHHHHHHHCCCCEEEEEE
DLRNNPGGLLSAAVESADLFLNQGIIVSTKSRSEGNQQFQALPSSEFLRLKMGILINHRS
EECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHCCCCHHHHEEEEEEEEECCC
ASAAEVFTAAMKDHQRAWVIGEKSYGKGVVQKLFPLPDGSALQMTVSHYYTPDGSMIEGK
CHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCCCEEEEEEEEEECCCCCEEECC
GIQPNQRYPLPADMKDETYLENVADLLLKQPKS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA