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The map label for this gene is gpmI

Identifier: 50083534

GI number: 50083534

Start: 255095

End: 256642

Strand: Direct

Name: gpmI

Synonym: ACIAD0256

Alternate gene names: 50083534

Gene position: 255095-256642 (Clockwise)

Preceding gene: 50083533

Following gene: 50083535

Centisome position: 7.09

GC content: 43.93

Gene sequence:

>1548_bases
ATGACGGATGCAACTGTTGCAAAAATCCCTCACGTTTTGGTGATCATGGATGGGATCGGACATCGCGAGGCAATCAAAGA
CAATGCGTTTTTGGCAGCGAAAACTCCTTCTCTTAGCATGATGAAACAAAAGCATCCGCATAGCCTGATTTCTGGCTCTG
GTGAAGATGTGGGATTACCAGATGGTCAAATGGGTAACTCTGAAGTTGGCCATATGAATCTGGGTGCTGGTCGTGTGCTG
TATCAGGACTTTACCCGCATTACCAAAGATATTCGTGATGGTGTTTTTTTTGAGCATGAGGTTTTAGTCGATGCTGTTGA
AAAAGCCAAAGCAGTGCATGGTGCTGTTCATATTATGGGTTTGCTCTCGGAAGGTGGTGTTCATTCACATGAAGATCATA
TCGTCGCCATGTGTGAATTGGCTTTAAAACGTGGTGCAACCGTTTATTTACACGCTTTCTTGGATGGTCGCGATACACCG
CCAAAAAGTGCACAGCCTTCTTTAGAAAAACTGGATGCACTTTTTGCTCAGTATCCAGAGCAAGGACGTATTGTGAGCAT
GATTGGTCGTTATTTTGCGATGGATCGTGACAATCGTTGGGATCGTGTTGAGCAGGCTTATCGTTTATTGACCGAAAGCG
AAGCAGTACGTACCGCACAAAGTGCAGTGCAGGGTCTGGAACTGGCATATGCTGCTGGTGAAAGCGATGAGTTTGTCAAA
GCAACACGTATTGGCGATGCCGTAGCCGTACAAGATGGTGACAGTATCGTGTTTATGAACTTCCGTGCCGACCGTGCCCG
TGAGTTAACACGTGCATTTGTAGAACACGATTTCTCAGGTTTTACACGCCAACGTATTCCACACCTTTCAAAATTTGTCA
TGCTGACACGTTATCAAGCTACCATTGATGCGCCAGTCGCTTATATGCCAGAAGCACTACATAATTCGATTGGTGAATAT
TTATCAAATTTGGGTAAGACACAGCTTCGTATTGCTGAAACTGAAAAATATGCTCATGTAACGTTTTTCTTTAGCGGTGG
ACGTGAAGACGAATATCCAGGTGAAAAACGTATTCTGATTCCATCACCAAATGTTGCCACCTATGATTTGAAACCAGAAA
TGAGTGCCTATGAAGTCACAGATCAATTGGTCAATGCCATTGATTCTGGTGAGTTTGATTTACTAGTTGTGAACTATGCC
AATGGTGATATGGTCGGTCATACAGGTATTTTCGATGCTGCAGTGAAGGCCGTTGAAGCAGTAGATACATGTCTAGGCCG
TGTTTACCAAGCCGTAATGGCAAAACATGGTCACATGATTATTACGGCAGATCATGGTAATGTGGAGCAAATGCAAGATT
ACCAAAGTGGTCAGGTGCATACACAACATACAACTGAACTGGTGCCATTTATTTATGTTGGCCCAACACAGGCAGTGATT
GCAGAAGGTGGTGTCTTGGCTGATGTGGCGCCAACATTACTCAATTTGATGCAACTTCCTGTACCTGCAGAAATGCAGGG
ACGTAATTTAATTACTCTCTCTTCATAA

Upstream 100 bases:

>100_bases
CATGATCAAGATCATGCAAAGTCATCATACAGACGTAGAGTCTTGATGGAAAATTCGGTAAGATAACGCGACGAAATTAT
AGGCATAACGAGAGTAAATC

Downstream 100 bases:

>100_bases
AGGTGACTGCATGGCTCAACGCTTCAATTATCGCGTTTTTTTAACAAGTGTGTTGATGTGTTTGAGTCCGCTTTCATTTG
CTGCCCCTCTGATTCAACCT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MTDATVAKIPHVLVIMDGIGHREAIKDNAFLAAKTPSLSMMKQKHPHSLISGSGEDVGLPDGQMGNSEVGHMNLGAGRVL
YQDFTRITKDIRDGVFFEHEVLVDAVEKAKAVHGAVHIMGLLSEGGVHSHEDHIVAMCELALKRGATVYLHAFLDGRDTP
PKSAQPSLEKLDALFAQYPEQGRIVSMIGRYFAMDRDNRWDRVEQAYRLLTESEAVRTAQSAVQGLELAYAAGESDEFVK
ATRIGDAVAVQDGDSIVFMNFRADRARELTRAFVEHDFSGFTRQRIPHLSKFVMLTRYQATIDAPVAYMPEALHNSIGEY
LSNLGKTQLRIAETEKYAHVTFFFSGGREDEYPGEKRILIPSPNVATYDLKPEMSAYEVTDQLVNAIDSGEFDLLVVNYA
NGDMVGHTGIFDAAVKAVEAVDTCLGRVYQAVMAKHGHMIITADHGNVEQMQDYQSGQVHTQHTTELVPFIYVGPTQAVI
AEGGVLADVAPTLLNLMQLPVPAEMQGRNLITLSS

Sequences:

>Translated_515_residues
MTDATVAKIPHVLVIMDGIGHREAIKDNAFLAAKTPSLSMMKQKHPHSLISGSGEDVGLPDGQMGNSEVGHMNLGAGRVL
YQDFTRITKDIRDGVFFEHEVLVDAVEKAKAVHGAVHIMGLLSEGGVHSHEDHIVAMCELALKRGATVYLHAFLDGRDTP
PKSAQPSLEKLDALFAQYPEQGRIVSMIGRYFAMDRDNRWDRVEQAYRLLTESEAVRTAQSAVQGLELAYAAGESDEFVK
ATRIGDAVAVQDGDSIVFMNFRADRARELTRAFVEHDFSGFTRQRIPHLSKFVMLTRYQATIDAPVAYMPEALHNSIGEY
LSNLGKTQLRIAETEKYAHVTFFFSGGREDEYPGEKRILIPSPNVATYDLKPEMSAYEVTDQLVNAIDSGEFDLLVVNYA
NGDMVGHTGIFDAAVKAVEAVDTCLGRVYQAVMAKHGHMIITADHGNVEQMQDYQSGQVHTQHTTELVPFIYVGPTQAVI
AEGGVLADVAPTLLNLMQLPVPAEMQGRNLITLSS
>Mature_514_residues
TDATVAKIPHVLVIMDGIGHREAIKDNAFLAAKTPSLSMMKQKHPHSLISGSGEDVGLPDGQMGNSEVGHMNLGAGRVLY
QDFTRITKDIRDGVFFEHEVLVDAVEKAKAVHGAVHIMGLLSEGGVHSHEDHIVAMCELALKRGATVYLHAFLDGRDTPP
KSAQPSLEKLDALFAQYPEQGRIVSMIGRYFAMDRDNRWDRVEQAYRLLTESEAVRTAQSAVQGLELAYAAGESDEFVKA
TRIGDAVAVQDGDSIVFMNFRADRARELTRAFVEHDFSGFTRQRIPHLSKFVMLTRYQATIDAPVAYMPEALHNSIGEYL
SNLGKTQLRIAETEKYAHVTFFFSGGREDEYPGEKRILIPSPNVATYDLKPEMSAYEVTDQLVNAIDSGEFDLLVVNYAN
GDMVGHTGIFDAAVKAVEAVDTCLGRVYQAVMAKHGHMIITADHGNVEQMQDYQSGQVHTQHTTELVPFIYVGPTQAVIA
EGGVLADVAPTLLNLMQLPVPAEMQGRNLITLSS

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=514, Percent_Identity=59.1439688715953, Blast_Score=609, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI32564249, Length=513, Percent_Identity=41.7153996101365, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17507741, Length=513, Percent_Identity=41.7153996101365, Blast_Score=390, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_ACIAD (Q6FFD5)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045044.1
- ProteinModelPortal:   Q6FFD5
- SMR:   Q6FFD5
- STRING:   Q6FFD5
- GeneID:   2878141
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0256
- NMPDR:   fig|62977.3.peg.529
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- PhylomeDB:   Q6FFD5
- ProtClustDB:   PRK05434
- BioCyc:   ASP62977:ACIAD0256-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 56583; Mature: 56452

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: ACT_SITE 67-67

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDATVAKIPHVLVIMDGIGHREAIKDNAFLAAKTPSLSMMKQKHPHSLISGSGEDVGLP
CCCCHHHHCCEEEEEECCCCCHHHHCCCCEEEECCCCHHHHHHCCCCHHHCCCCCCCCCC
DGQMGNSEVGHMNLGAGRVLYQDFTRITKDIRDGVFFEHEVLVDAVEKAKAVHGAVHIMG
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHH
LLSEGGVHSHEDHIVAMCELALKRGATVYLHAFLDGRDTPPKSAQPSLEKLDALFAQYPE
HHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCC
QGRIVSMIGRYFAMDRDNRWDRVEQAYRLLTESEAVRTAQSAVQGLELAYAAGESDEFVK
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHH
ATRIGDAVAVQDGDSIVFMNFRADRARELTRAFVEHDFSGFTRQRIPHLSKFVMLTRYQA
HHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TIDAPVAYMPEALHNSIGEYLSNLGKTQLRIAETEKYAHVTFFFSGGREDEYPGEKRILI
HCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCEEEE
PSPNVATYDLKPEMSAYEVTDQLVNAIDSGEFDLLVVNYANGDMVGHTGIFDAAVKAVEA
CCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHH
VDTCLGRVYQAVMAKHGHMIITADHGNVEQMQDYQSGQVHTQHTTELVPFIYVGPTQAVI
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCEEECCHHCCCCEEEECCCHHHH
AEGGVLADVAPTLLNLMQLPVPAEMQGRNLITLSS
HCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
TDATVAKIPHVLVIMDGIGHREAIKDNAFLAAKTPSLSMMKQKHPHSLISGSGEDVGLP
CCCHHHHCCEEEEEECCCCCHHHHCCCCEEEECCCCHHHHHHCCCCHHHCCCCCCCCCC
DGQMGNSEVGHMNLGAGRVLYQDFTRITKDIRDGVFFEHEVLVDAVEKAKAVHGAVHIMG
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHH
LLSEGGVHSHEDHIVAMCELALKRGATVYLHAFLDGRDTPPKSAQPSLEKLDALFAQYPE
HHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCC
QGRIVSMIGRYFAMDRDNRWDRVEQAYRLLTESEAVRTAQSAVQGLELAYAAGESDEFVK
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHH
ATRIGDAVAVQDGDSIVFMNFRADRARELTRAFVEHDFSGFTRQRIPHLSKFVMLTRYQA
HHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TIDAPVAYMPEALHNSIGEYLSNLGKTQLRIAETEKYAHVTFFFSGGREDEYPGEKRILI
HCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCEEEE
PSPNVATYDLKPEMSAYEVTDQLVNAIDSGEFDLLVVNYANGDMVGHTGIFDAAVKAVEA
CCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHH
VDTCLGRVYQAVMAKHGHMIITADHGNVEQMQDYQSGQVHTQHTTELVPFIYVGPTQAVI
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCEEECCHHCCCCEEEECCCHHHH
AEGGVLADVAPTLLNLMQLPVPAEMQGRNLITLSS
HCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA