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The map label for this gene is dinP

Identifier: 50083505

GI number: 50083505

Start: 224762

End: 225817

Strand: Reverse

Name: dinP

Synonym: ACIAD0225

Alternate gene names: 50083505

Gene position: 225817-224762 (Counterclockwise)

Preceding gene: 50083506

Following gene: 50083504

Centisome position: 6.28

GC content: 41.1

Gene sequence:

>1056_bases
ATGAGAAAAATCATTCACATTGATATGGATGCCTTTTATGCATCTGTCGAATTGCGGGAGCGACCAGAGCTTAAAACGCT
TCCTGTTGTTATTTCATCACATCATCCCCGTGCCGTTATTGCAGCAGCTTCATATCCAGCCCGGGTCTATGGGTTACGCT
CTGCCATGCCGATGGGACAAGCCAGAAAGCTGTGTCCGGATCTCATTATTATTGAACCTAATTTTGATAAATATCGCGCG
GTTTCTCACCAGATTCACCAAATCTTTCAACAGCATACCCATATTATTGAACCGCTTTCTTTAGATGAAGCGTATTTGGA
TGTGACTGAAAATTTAAACAATTTACCCAGCGCAACCGATGTTGCCATTCAGATCCGACAACAGATCTGGGAGCAAACAA
GTCTTACTGCATCTGCAGGGGTTGCACCCAATAAATTTTTGGCAAAAATTGCCTCCGACTGGAATAAACCCAACGGCCTT
TGTGTGATTAAACCGCATCAGGTGATGCAGTTTATACAAAATCTACCCTTAAAAAAAATTCCTGGTGTAGGACGCGTCAC
CCAAGACAAACTACAGCAGCTTAAACTTGAAACACTTGGAGATTTACAACACATCGAAGAAGCGGTACTCATTCAGCACT
TTGGTAAATATGGCAAACAGCTCTATTTATATGCCCAAGGGATCGATCATCGGTCAGTACAAGCTGAACGTGTCCGTCAA
CAAATTTCCAAAGAAACCACCTTTGATCAGGATCTGTATCTTCATGAATGTTCAAGCTACTGGCTGATGCTTGCAGAAAA
AGTATGGCAATCGCTTCAAAACAAAAACTTACAGGCACGTGGGGTAAATATCAAACTAAAAAATAAACATTTTCAGGTTT
TTCAGCACAGCAAAAGCTTTAAACGTGCCCTGCAATCACTGGATGAATTTAAATCAGTTTTAGCGCTGTTATTACAAGAA
ATTTCCTTAACCTTAGATGATCAATACCGCTTAATTGGCGTTGGACTCTATCAATTAAGTCCAAGTGCAAGTGAATCACA
ACTCACTTTGTGGTAG

Upstream 100 bases:

>100_bases
AAGGAATTGAAAAGCCTGTTGATCTCAATGTTTATGCAGGTTCATTACAACACTGGCAACAGTTTGTAAATCAAAAATCT
CAAATCACAAATACAGTAAA

Downstream 100 bases:

>100_bases
TCGTATTTTTTTTACACAAAAATTTAAATTCTTGATCAAAGCTATTTCACATTGAATAAATTTTAGAGTAATCTTAGCCA
CGCAAATGCATTTACCCATG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRKIIHIDMDAFYASVELRERPELKTLPVVISSHHPRAVIAAASYPARVYGLRSAMPMGQARKLCPDLIIIEPNFDKYRA
VSHQIHQIFQQHTHIIEPLSLDEAYLDVTENLNNLPSATDVAIQIRQQIWEQTSLTASAGVAPNKFLAKIASDWNKPNGL
CVIKPHQVMQFIQNLPLKKIPGVGRVTQDKLQQLKLETLGDLQHIEEAVLIQHFGKYGKQLYLYAQGIDHRSVQAERVRQ
QISKETTFDQDLYLHECSSYWLMLAEKVWQSLQNKNLQARGVNIKLKNKHFQVFQHSKSFKRALQSLDEFKSVLALLLQE
ISLTLDDQYRLIGVGLYQLSPSASESQLTLW

Sequences:

>Translated_351_residues
MRKIIHIDMDAFYASVELRERPELKTLPVVISSHHPRAVIAAASYPARVYGLRSAMPMGQARKLCPDLIIIEPNFDKYRA
VSHQIHQIFQQHTHIIEPLSLDEAYLDVTENLNNLPSATDVAIQIRQQIWEQTSLTASAGVAPNKFLAKIASDWNKPNGL
CVIKPHQVMQFIQNLPLKKIPGVGRVTQDKLQQLKLETLGDLQHIEEAVLIQHFGKYGKQLYLYAQGIDHRSVQAERVRQ
QISKETTFDQDLYLHECSSYWLMLAEKVWQSLQNKNLQARGVNIKLKNKHFQVFQHSKSFKRALQSLDEFKSVLALLLQE
ISLTLDDQYRLIGVGLYQLSPSASESQLTLW
>Mature_351_residues
MRKIIHIDMDAFYASVELRERPELKTLPVVISSHHPRAVIAAASYPARVYGLRSAMPMGQARKLCPDLIIIEPNFDKYRA
VSHQIHQIFQQHTHIIEPLSLDEAYLDVTENLNNLPSATDVAIQIRQQIWEQTSLTASAGVAPNKFLAKIASDWNKPNGL
CVIKPHQVMQFIQNLPLKKIPGVGRVTQDKLQQLKLETLGDLQHIEEAVLIQHFGKYGKQLYLYAQGIDHRSVQAERVRQ
QISKETTFDQDLYLHECSSYWLMLAEKVWQSLQNKNLQARGVNIKLKNKHFQVFQHSKSFKRALQSLDEFKSVLALLLQE
ISLTLDDQYRLIGVGLYQLSPSASESQLTLW

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=30.4733727810651, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=30.3834808259587, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI7705344, Length=414, Percent_Identity=31.1594202898551, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI154350220, Length=295, Percent_Identity=27.7966101694915, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI5729982, Length=347, Percent_Identity=25.6484149855908, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1786425, Length=300, Percent_Identity=48, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI1787432, Length=217, Percent_Identity=29.0322580645161, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193205700, Length=402, Percent_Identity=31.0945273631841, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI193205702, Length=348, Percent_Identity=29.8850574712644, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17537959, Length=259, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115534089, Length=364, Percent_Identity=24.4505494505494, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324921, Length=248, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19923006, Length=339, Percent_Identity=30.6784660766962, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21355641, Length=251, Percent_Identity=28.2868525896414, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24644984, Length=251, Percent_Identity=28.2868525896414, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24668444, Length=121, Percent_Identity=33.0578512396694, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_ACIAD (Q6FFG4)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045015.1
- HSSP:   Q9UHC5
- ProteinModelPortal:   Q6FFG4
- SMR:   Q6FFG4
- STRING:   Q6FFG4
- GeneID:   2881103
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0225
- NMPDR:   fig|62977.3.peg.430
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   VICAASY
- PhylomeDB:   Q6FFG4
- ProtClustDB:   PRK02406
- BioCyc:   ASP62977:ACIAD0225-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 40193; Mature: 40193

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 103-103

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHIDMDAFYASVELRERPELKTLPVVISSHHPRAVIAAASYPARVYGLRSAMPMGQ
CCEEEEEEHHHHHHHHHHCCCCCCCEECEEEECCCCCEEEEECCCCHHHHHHHHCCCCCH
ARKLCPDLIIIEPNFDKYRAVSHQIHQIFQQHTHIIEPLSLDEAYLDVTENLNNLPSATD
HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHH
VAIQIRQQIWEQTSLTASAGVAPNKFLAKIASDWNKPNGLCVIKPHQVMQFIQNLPLKKI
HHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCHHHC
PGVGRVTQDKLQQLKLETLGDLQHIEEAVLIQHFGKYGKQLYLYAQGIDHRSVQAERVRQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHH
QISKETTFDQDLYLHECSSYWLMLAEKVWQSLQNKNLQARGVNIKLKNKHFQVFQHSKSF
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEECCCHHHHHHHHHHH
KRALQSLDEFKSVLALLLQEISLTLDDQYRLIGVGLYQLSPSASESQLTLW
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCEEEC
>Mature Secondary Structure
MRKIIHIDMDAFYASVELRERPELKTLPVVISSHHPRAVIAAASYPARVYGLRSAMPMGQ
CCEEEEEEHHHHHHHHHHCCCCCCCEECEEEECCCCCEEEEECCCCHHHHHHHHCCCCCH
ARKLCPDLIIIEPNFDKYRAVSHQIHQIFQQHTHIIEPLSLDEAYLDVTENLNNLPSATD
HHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHH
VAIQIRQQIWEQTSLTASAGVAPNKFLAKIASDWNKPNGLCVIKPHQVMQFIQNLPLKKI
HHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCHHHC
PGVGRVTQDKLQQLKLETLGDLQHIEEAVLIQHFGKYGKQLYLYAQGIDHRSVQAERVRQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHH
QISKETTFDQDLYLHECSSYWLMLAEKVWQSLQNKNLQARGVNIKLKNKHFQVFQHSKSF
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEECCCHHHHHHHHHHH
KRALQSLDEFKSVLALLLQEISLTLDDQYRLIGVGLYQLSPSASESQLTLW
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA