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The map label for this gene is bolA [H]

Identifier: 50083429

GI number: 50083429

Start: 145763

End: 146071

Strand: Direct

Name: bolA [H]

Synonym: ACIAD0142

Alternate gene names: 50083429

Gene position: 145763-146071 (Clockwise)

Preceding gene: 50083428

Following gene: 50083430

Centisome position: 4.05

GC content: 43.69

Gene sequence:

>309_bases
ATGAGTCTTGAGCAACAATTGATTGAGCGTTTAACGACACTTGCACCAGTTCATTTGGAAGTGATCAATGAATCATCAGG
TCACGGTGGATATTTTCCTGGTAAGGAAAGTCATTTCAAAGTTGTTGTCGTAAGCAACGAATTTAATGGATTACGTTTGG
TTCAACGCCATCAAAAAGTGTATGCAGTTGCTTCAGATTTAATGAGTCCTGGCCGTATTCATGCTCTCGCGATTCATGCG
TATGTACCAGAAGAATGGCAGGGACAGTCGCCAGCCAGTCCAGAATGTGCGCATGCCCCAAAAGCTTGA

Upstream 100 bases:

>100_bases
TTACGTCATAAAATCTACAGATGTTATGGTGTTGAATGTCAGAAAAACACAAAGAACAGGTTATACTGCCATGACCTTTC
ATCCATAAAAAGGATATAGC

Downstream 100 bases:

>100_bases
GTAGATAAAAGATGGATGCACACTTAATCACCAAAATTATTCATATGACAGCCGTTGCTCTGTCATTACTGGTGTTTGTT
TTCCGCGCAGCGACATTATT

Product: activator of morphogenic pathway (BolA), important in general stress response

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MSLEQQLIERLTTLAPVHLEVINESSGHGGYFPGKESHFKVVVVSNEFNGLRLVQRHQKVYAVASDLMSPGRIHALAIHA
YVPEEWQGQSPASPECAHAPKA

Sequences:

>Translated_102_residues
MSLEQQLIERLTTLAPVHLEVINESSGHGGYFPGKESHFKVVVVSNEFNGLRLVQRHQKVYAVASDLMSPGRIHALAIHA
YVPEEWQGQSPASPECAHAPKA
>Mature_101_residues
SLEQQLIERLTTLAPVHLEVINESSGHGGYFPGKESHFKVVVVSNEFNGLRLVQRHQKVYAVASDLMSPGRIHALAIHAY
VPEEWQGQSPASPECAHAPKA

Specific function: Plays An Important Role In General Stress Response (Heat Shock, Acidic Stress, Oxidative Stress, Carbon-Starvation Stress And Osmotic Shock). Involved In Morphogenetic Pathway. Has A Role Is The Induction Of The Expression Of Daca (Pbp5), Dacc (Pbp6) And

COG id: COG0271

COG function: function code T; Stress-induced morphogen (activity unknown)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bolA/yrbA family [H]

Homologues:

Organism=Homo sapiens, GI7705638, Length=85, Percent_Identity=45.8823529411765, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081740, Length=101, Percent_Identity=41.5841584158416, Blast_Score=74, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221459039, Length=91, Percent_Identity=43.956043956044, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002634 [H]

Pfam domain/function: PF01722 BolA [H]

EC number: NA

Molecular weight: Translated: 11225; Mature: 11094

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEQQLIERLTTLAPVHLEVINESSGHGGYFPGKESHFKVVVVSNEFNGLRLVQRHQKV
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
YAVASDLMSPGRIHALAIHAYVPEEWQGQSPASPECAHAPKA
HHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLEQQLIERLTTLAPVHLEVINESSGHGGYFPGKESHFKVVVVSNEFNGLRLVQRHQKV
CHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
YAVASDLMSPGRIHALAIHAYVPEEWQGQSPASPECAHAPKA
HHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7805867 [H]