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The map label for this gene is nahR [H]

Identifier: 50083395

GI number: 50083395

Start: 104308

End: 105207

Strand: Reverse

Name: nahR [H]

Synonym: ACIAD0105

Alternate gene names: 50083395

Gene position: 105207-104308 (Counterclockwise)

Preceding gene: 50083401

Following gene: 50083394

Centisome position: 2.92

GC content: 41.0

Gene sequence:

>900_bases
ATGTTTGATCTCGATAGCCGATTACTCAATATTTTTTATCATGTATATAAATCAAAAAGTGTCTCTGCAGCCGCAGATGC
GATTGGTGTTAGCCAGCCAACCATCAGCAATGGTCTGATTAAAATTCGCCAGCATTTTGGTGATCCGCTGTTTTTGCGTG
TGGGCAATGAAATGATTCCCACCGAATTGTCCAAGCAAATTTTTCCGCTGATTAGTGAAGTAATCAACAAAGTTGAAAGC
ATCAATAATTTCAGTGTCAATTTTGATCCTTCCAAATCAGATTTGTTGTATACCTTGGCGATGACGGATGTTTCACATCT
GGTACTTTTGCCGCAAATTACCCAGTTTCTCAATAAAAATGCGCCTTTTATCCGTCTCAATGTACGCCCGATTAGCTCTG
AAACCAGTTATCAGATGGCAAATGGTGAAATTGATCTGGCCATTGGTTTTTTACCACAGCTTGAAGATGGTTTTTATCAG
CAGAAACTGTTCTCACAGCGCTACGTGGTAATTTCACGGAAAAATCATCCACGTCTTAAAGAGGAACGAATTAGCGTCGA
TGATTATATCCGAGAAATGCATATCGATATTGATGCTGGTGCAGGTCATTATCACATCGAAAACGAATTACAAAACAAGG
GACTAAAACGTAATGTCCTGATTCGTCTACCGAGTTATCTCGGTGTCGGTCTAGTGGTTCAGGAGACAGATGCCATTGCA
ACTGTGCCTTATTATCTGAGTCAGGTACTATTGGCACGGGGTAACTTACAAATTTTTGATGCGCCGCTAGATTTTCCAAC
CTATAGCATCAAACAGCACTGGCACATGTGCTGCCATCACAAGACCAGCCACCAGTGGTTTCGTCAAGCCTGTCACGAAA
TTTTCAAAACTATTGTTTAA

Upstream 100 bases:

>100_bases
TCTGTTTATAAAGTTCAATGATATAATTTGAAATTAAATATTTACATCACGAGCAGTCGGTCTCTTCTATTTGCTTCACG
GTGGTTAAGGAAAAAAGAGA

Downstream 100 bases:

>100_bases
TTAAGCACTTATTTAATTTCTTCATTTATATTTAGATGCAATTTTAAAATAAAAACTCTGATTTTCGGCATAAAACGATC
ATATTTTTTTCGTATTGCTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MFDLDSRLLNIFYHVYKSKSVSAAADAIGVSQPTISNGLIKIRQHFGDPLFLRVGNEMIPTELSKQIFPLISEVINKVES
INNFSVNFDPSKSDLLYTLAMTDVSHLVLLPQITQFLNKNAPFIRLNVRPISSETSYQMANGEIDLAIGFLPQLEDGFYQ
QKLFSQRYVVISRKNHPRLKEERISVDDYIREMHIDIDAGAGHYHIENELQNKGLKRNVLIRLPSYLGVGLVVQETDAIA
TVPYYLSQVLLARGNLQIFDAPLDFPTYSIKQHWHMCCHHKTSHQWFRQACHEIFKTIV

Sequences:

>Translated_299_residues
MFDLDSRLLNIFYHVYKSKSVSAAADAIGVSQPTISNGLIKIRQHFGDPLFLRVGNEMIPTELSKQIFPLISEVINKVES
INNFSVNFDPSKSDLLYTLAMTDVSHLVLLPQITQFLNKNAPFIRLNVRPISSETSYQMANGEIDLAIGFLPQLEDGFYQ
QKLFSQRYVVISRKNHPRLKEERISVDDYIREMHIDIDAGAGHYHIENELQNKGLKRNVLIRLPSYLGVGLVVQETDAIA
TVPYYLSQVLLARGNLQIFDAPLDFPTYSIKQHWHMCCHHKTSHQWFRQACHEIFKTIV
>Mature_299_residues
MFDLDSRLLNIFYHVYKSKSVSAAADAIGVSQPTISNGLIKIRQHFGDPLFLRVGNEMIPTELSKQIFPLISEVINKVES
INNFSVNFDPSKSDLLYTLAMTDVSHLVLLPQITQFLNKNAPFIRLNVRPISSETSYQMANGEIDLAIGFLPQLEDGFYQ
QKLFSQRYVVISRKNHPRLKEERISVDDYIREMHIDIDAGAGHYHIENELQNKGLKRNVLIRLPSYLGVGLVVQETDAIA
TVPYYLSQVLLARGNLQIFDAPLDFPTYSIKQHWHMCCHHKTSHQWFRQACHEIFKTIV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=25.0836120401338, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI87081766, Length=253, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786820, Length=271, Percent_Identity=24.7232472324723, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790147, Length=309, Percent_Identity=23.6245954692557, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34287; Mature: 34287

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDLDSRLLNIFYHVYKSKSVSAAADAIGVSQPTISNGLIKIRQHFGDPLFLRVGNEMIP
CCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCH
TELSKQIFPLISEVINKVESINNFSVNFDPSKSDLLYTLAMTDVSHLVLLPQITQFLNKN
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCC
APFIRLNVRPISSETSYQMANGEIDLAIGFLPQLEDGFYQQKLFSQRYVVISRKNHPRLK
CCEEEEEEEECCCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCHH
EERISVDDYIREMHIDIDAGAGHYHIENELQNKGLKRNVLIRLPSYLGVGLVVQETDAIA
HHHCCHHHHHHHHEEEEECCCCCEEEHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHH
TVPYYLSQVLLARGNLQIFDAPLDFPTYSIKQHWHMCCHHKTSHQWFRQACHEIFKTIV
HHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFDLDSRLLNIFYHVYKSKSVSAAADAIGVSQPTISNGLIKIRQHFGDPLFLRVGNEMIP
CCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCH
TELSKQIFPLISEVINKVESINNFSVNFDPSKSDLLYTLAMTDVSHLVLLPQITQFLNKN
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCC
APFIRLNVRPISSETSYQMANGEIDLAIGFLPQLEDGFYQQKLFSQRYVVISRKNHPRLK
CCEEEEEEEECCCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCHH
EERISVDDYIREMHIDIDAGAGHYHIENELQNKGLKRNVLIRLPSYLGVGLVVQETDAIA
HHHCCHHHHHHHHEEEEECCCCCEEEHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHH
TVPYYLSQVLLARGNLQIFDAPLDFPTYSIKQHWHMCCHHKTSHQWFRQACHEIFKTIV
HHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]