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The map label for this gene is wza [H]

Identifier: 50083363

GI number: 50083363

Start: 66934

End: 68037

Strand: Reverse

Name: wza [H]

Synonym: ACIAD0070

Alternate gene names: 50083363

Gene position: 68037-66934 (Counterclockwise)

Preceding gene: 50083377

Following gene: 50083362

Centisome position: 1.89

GC content: 43.03

Gene sequence:

>1104_bases
GTGAAGCTTTACCAATCATTGATTATTCTAAGTTTGAGTTTGGGCTCTTTTGGATGTGCCGTTACATCTGGTCTACAGTC
CTACGATGTCCCAGATCAAGGTCGCTATGAGACCAATCTCGGTGCTGTTTTAAATGTTGTAAAGCTTACGCCAGAAACTG
TTCAAGCTTTTTCGCTTGATCATGCAGTAGTGCAGCAAAATTATGCTGCCCTGTTTAAAGATCAACGTGTCGCTTATCGC
CTGACCAATGGCGATGTGCTCTCGATTCAGTTATGGGCATATCCAGAAATCACTCCTCCATTAGGCAATAATGTAAGTAA
TGATCTTTCTGCTCAGTCAATAGGTTATCCGATTGACTCTTCAGGCTATATTCAGTTTCCACTGATTGGTCGCTACAAGG
CAGAAGGTAAAACACTAGAACAAGTCAACCGTGAGTTGCCACAGCTTCTCAAACGTTATTTAAAAAATCCAGACCTTACG
GCACGTGTGATTTCTTATGAGGGTAAACCGTACTCTGTACAAGGTAACGTGACCAAAGGCGGTGTTTTTTATCTTAGAGA
CCAACCGATTAGTGTTTATACGGCTTTGGGGCTGGCAGGCGGTGTCACAGAGCTTGGCGATAATACTTCTGTTCGACTCA
TACGTAACGGTGTGACATATAACTTAAACACCATTGAGCTTGAAAAAGCGGGTTATTCACTGCATAAGTTACTGTTACAG
CCAGACGATACCCTGTATGTCAATGCCCGTGAAAACCAGAAAATTTATGTGATGGGTGAAGCACAAAAGAATCAGGCTCT
ACCGATGCGTGATCAAGGTATGACCTTGAGTGACGTACTGGGTGAAAGTTTAGGTATCAACCCAACTTCTGCAAGCGCTA
GCAGAGTCTATGTGCTTAGAACCAACCCCAAAGATCACACCAGTGAATTGTTTCATCTCAACCTGATGAGCCTTGGTGAC
TTTAGCCTTGCCAATCAATTTCAGATGAAAAGTAATGATATTGTATATGTCGATGCGACAGGCCTGACTCGCTGGCAGCG
TGTGGTCAATCAGATTATTCCATTTTCAAATGCCTTATATAATCTTGACCGTCTAGGACAGTGA

Upstream 100 bases:

>100_bases
TTTTTAAATTTCTTTTTCGGTACAATGCATGTAATTTGAGGTATTCTTAGCTTCGATTGAAGCTATAATTTTATTTATAA
ATAAACATCAAGGGTCGCGC

Downstream 100 bases:

>100_bases
TGCAAATCAAACATATTTTAGTGGTATGCATTGGTAATATTTGCCGTAGCCCAATGGCCGAATACTTGCTTAAAGCACAA
TACCCTGAGCTTCACATTGA

Product: polysaccharide exporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKLYQSLIILSLSLGSFGCAVTSGLQSYDVPDQGRYETNLGAVLNVVKLTPETVQAFSLDHAVVQQNYAALFKDQRVAYR
LTNGDVLSIQLWAYPEITPPLGNNVSNDLSAQSIGYPIDSSGYIQFPLIGRYKAEGKTLEQVNRELPQLLKRYLKNPDLT
ARVISYEGKPYSVQGNVTKGGVFYLRDQPISVYTALGLAGGVTELGDNTSVRLIRNGVTYNLNTIELEKAGYSLHKLLLQ
PDDTLYVNARENQKIYVMGEAQKNQALPMRDQGMTLSDVLGESLGINPTSASASRVYVLRTNPKDHTSELFHLNLMSLGD
FSLANQFQMKSNDIVYVDATGLTRWQRVVNQIIPFSNALYNLDRLGQ

Sequences:

>Translated_367_residues
MKLYQSLIILSLSLGSFGCAVTSGLQSYDVPDQGRYETNLGAVLNVVKLTPETVQAFSLDHAVVQQNYAALFKDQRVAYR
LTNGDVLSIQLWAYPEITPPLGNNVSNDLSAQSIGYPIDSSGYIQFPLIGRYKAEGKTLEQVNRELPQLLKRYLKNPDLT
ARVISYEGKPYSVQGNVTKGGVFYLRDQPISVYTALGLAGGVTELGDNTSVRLIRNGVTYNLNTIELEKAGYSLHKLLLQ
PDDTLYVNARENQKIYVMGEAQKNQALPMRDQGMTLSDVLGESLGINPTSASASRVYVLRTNPKDHTSELFHLNLMSLGD
FSLANQFQMKSNDIVYVDATGLTRWQRVVNQIIPFSNALYNLDRLGQ
>Mature_367_residues
MKLYQSLIILSLSLGSFGCAVTSGLQSYDVPDQGRYETNLGAVLNVVKLTPETVQAFSLDHAVVQQNYAALFKDQRVAYR
LTNGDVLSIQLWAYPEITPPLGNNVSNDLSAQSIGYPIDSSGYIQFPLIGRYKAEGKTLEQVNRELPQLLKRYLKNPDLT
ARVISYEGKPYSVQGNVTKGGVFYLRDQPISVYTALGLAGGVTELGDNTSVRLIRNGVTYNLNTIELEKAGYSLHKLLLQ
PDDTLYVNARENQKIYVMGEAQKNQALPMRDQGMTLSDVLGESLGINPTSASASRVYVLRTNPKDHTSELFHLNLMSLGD
FSLANQFQMKSNDIVYVDATGLTRWQRVVNQIIPFSNALYNLDRLGQ

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=360, Percent_Identity=29.4444444444444, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1788376, Length=356, Percent_Identity=28.3707865168539, Blast_Score=162, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 40701; Mature: 40701

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYQSLIILSLSLGSFGCAVTSGLQSYDVPDQGRYETNLGAVLNVVKLTPETVQAFSLD
CCHHHEEEEEEECCCCCCHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
HAVVQQNYAALFKDQRVAYRLTNGDVLSIQLWAYPEITPPLGNNVSNDLSAQSIGYPIDS
HHHHHHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCC
SGYIQFPLIGRYKAEGKTLEQVNRELPQLLKRYLKNPDLTARVISYEGKPYSVQGNVTKG
CCEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCEEC
GVFYLRDQPISVYTALGLAGGVTELGDNTSVRLIRNGVTYNLNTIELEKAGYSLHKLLLQ
CEEEEECCCCEEEEEHHHCCCHHHCCCCCEEEEEECCCEEEEEEEEEECCCCCEEHEEEC
PDDTLYVNARENQKIYVMGEAQKNQALPMRDQGMTLSDVLGESLGINPTSASASRVYVLR
CCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEE
TNPKDHTSELFHLNLMSLGDFSLANQFQMKSNDIVYVDATGLTRWQRVVNQIIPFSNALY
CCCCCCCCCEEEEEEEECCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHCCCHHHHH
NLDRLGQ
HHHHCCC
>Mature Secondary Structure
MKLYQSLIILSLSLGSFGCAVTSGLQSYDVPDQGRYETNLGAVLNVVKLTPETVQAFSLD
CCHHHEEEEEEECCCCCCHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
HAVVQQNYAALFKDQRVAYRLTNGDVLSIQLWAYPEITPPLGNNVSNDLSAQSIGYPIDS
HHHHHHHHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHCCCCCCC
SGYIQFPLIGRYKAEGKTLEQVNRELPQLLKRYLKNPDLTARVISYEGKPYSVQGNVTKG
CCEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCEEC
GVFYLRDQPISVYTALGLAGGVTELGDNTSVRLIRNGVTYNLNTIELEKAGYSLHKLLLQ
CEEEEECCCCEEEEEHHHCCCHHHCCCCCEEEEEECCCEEEEEEEEEECCCCCEEHEEEC
PDDTLYVNARENQKIYVMGEAQKNQALPMRDQGMTLSDVLGESLGINPTSASASRVYVLR
CCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEE
TNPKDHTSELFHLNLMSLGDFSLANQFQMKSNDIVYVDATGLTRWQRVVNQIIPFSNALY
CCCCCCCCCEEEEEEEECCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHCCCHHHHH
NLDRLGQ
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]