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The map label for this gene is ushA [C]

Identifier: 50083311

GI number: 50083311

Start: 15927

End: 17882

Strand: Direct

Name: ushA [C]

Synonym: ACIAD0015

Alternate gene names: 50083311

Gene position: 15927-17882 (Clockwise)

Preceding gene: 50083310

Following gene: 50083312

Centisome position: 0.44

GC content: 41.05

Gene sequence:

>1956_bases
ATGCTTTCTAAAAAATTAACAACCTTACAAATTTCTCTTTTCAACATTTCGAATATGTTAACTCCAATTGCGCTGATGTT
CGCTATATCCATGGGGATGAGTGGGTGTAAAGAACACCATGATTCTGGGTCATCAACTACAGTTATCCCGCCAGAAAACA
GTGCGTCCGATGATTCAAGTTTGAAGATTATTCATATCAATGACCATCATTCGCATCTGGATGAAGAGCGCATGGAGTTT
GATCTGAATACAGGCAGTACTTCAGGCACTTATAGTGTAAGTCGTGGTGGTTTTGCACGTGTGTCAGCGCTTTTTAATCA
GCTTGCCATGGGACATGGAGCAATTTTAAAACTGCACGCTGGGGATGCAACCACTGGTGACCTGTATTACAACCTCACAA
AAGGCAAGGCAGATGCTGATGTAATGAATATGATTTGCTTTGATGCATTTACATTGGGAAATCATGAATTTGATAATAAA
GATCAAGGACTAAAATACTTCATTGATGCATTGGATCAAGGCGATTGTCCAACACGTACTGCGATTTTATCTGCAAATGT
GGAATTTGGACCGTCATCTCCATTGTATCAAAGCACCCGTATTCAAAAATCAACAGTGATTGAAACTCAAGGTCAAAAGA
TTGGTCTTGTAGGACTCACCATCGCACAGAAAACCAAAAATGCTTCTCAGCCTAATCCCGATACCCTGTTTAAAGATGAA
CTAGAAAGTGCACAGCAGCAAATAGACCTATTACGTCAAGCAGGCATTAATAAGATCATCCTACAAAGTCATGTGGGTTA
TGAAATGGATAAATATCTTGCGACACAATTACATGGTGTAGATGTGATTGTAGGAGGTGATTCACATACGCTGTTAGGTT
CACAGAATCTTGAGAAAGTTGGAATGACGCCAGAAGCACCTTATCCGACCACCCTCCAAAATAAGGATGGTGATCCAGTG
TGTATAGTTCAGGCGTGGCAGTACAGTTACGTGGTCGGCGAGCTGGATATAACATTTGACTCTCAGGGCCGCGTTAAAAA
CTGTCAAGGTACACCGCATATTTTGATTGGAGATGATTTTAAACCTAAACTCACGTCTGCACCTGCCTTAACCCATGATC
AGCAGTTAAACATAGCCAAGCAGTTACATCTGCTTGCCCCTGAAATTACAGTGATTGAACCAGATAGTAGAACATCACAA
ATTCTAAGCCCCTATCGTGATATGAAAGAAAAATTTCGACAAACGATTGTGGCGACGGCTCAGGAAATTTTATGTTTACG
CCGTGTACCAGGAACACAACGTGATATTAACCGTTCCAGTTTAGGCAATGTATGTAATCAGGATGAACGGGTGAATCGTT
ACGGTGGAGATATTCAGCAGCTGGTTGCAGAAGCCTTTTTACAGCAAGGAAAAACTTACTTCTCTGCACAACTATCAATT
TTAAATGGGGGCGGCGTACGTACCGATGTAGAACAAGGACCGATCAGTGTAGAAAAAGTTTATCAGGTCCTGCCTTATAA
CAGTACGCTGGTACAGTTAAATATGCAGGGGAATGAGATCAAGGCCACTCTTGAAGATGCAGTTGATGCGGTTATTACGC
TGAATAATACAGGCAGTTATCCTTATACAGCAGGATTACGCTGGTCAGTCGACTTTAATCAACCAAAAGGTCAACGCATT
AGCAACATTGAATTGAAAGATTCATCTGGAGAATATAGCTTACTCATGATGGATCAGACTTATCGTGTAGTAACACTTGA
TTTTCTCGCCAATGGTTCAGATTATTATCATACCCTTGCAACCATTCGTAATGAGCGACGTATCGATGTAGGTTTGGATT
ATGCAGAAGCCTTTATGAAATATCTTGAAGCAGATGGCTTATCCCAACCGAGAGCATTATTTCGTTTACCTGTTTCCAAT
TACAGTACGCAATACTTTATTGATCGGCCTCTGTGA

Upstream 100 bases:

>100_bases
TTTATAATTTGCATGCTTTGGATTCTTGGTTCAGAAGACCATGAGGTCATCTAGATAGAAGATGAATGACATGAATATCC
AAATAGTGTGACGATGAATG

Downstream 100 bases:

>100_bases
AACTTTAAAACTCACAAAAAATAGCGTGAAGTCTAAAATTTAAGCATAACTGAATGGGCAGATGACTAAAATCGTCTGCT
TATTCGCCATAAAATCAAGA

Product: 5'-nucleotidase NucA precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MLSKKLTTLQISLFNISNMLTPIALMFAISMGMSGCKEHHDSGSSTTVIPPENSASDDSSLKIIHINDHHSHLDEERMEF
DLNTGSTSGTYSVSRGGFARVSALFNQLAMGHGAILKLHAGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNK
DQGLKYFIDALDQGDCPTRTAILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPDTLFKDE
LESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLLGSQNLEKVGMTPEAPYPTTLQNKDGDPV
CIVQAWQYSYVVGELDITFDSQGRVKNCQGTPHILIGDDFKPKLTSAPALTHDQQLNIAKQLHLLAPEITVIEPDSRTSQ
ILSPYRDMKEKFRQTIVATAQEILCLRRVPGTQRDINRSSLGNVCNQDERVNRYGGDIQQLVAEAFLQQGKTYFSAQLSI
LNGGGVRTDVEQGPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVITLNNTGSYPYTAGLRWSVDFNQPKGQRI
SNIELKDSSGEYSLLMMDQTYRVVTLDFLANGSDYYHTLATIRNERRIDVGLDYAEAFMKYLEADGLSQPRALFRLPVSN
YSTQYFIDRPL

Sequences:

>Translated_651_residues
MLSKKLTTLQISLFNISNMLTPIALMFAISMGMSGCKEHHDSGSSTTVIPPENSASDDSSLKIIHINDHHSHLDEERMEF
DLNTGSTSGTYSVSRGGFARVSALFNQLAMGHGAILKLHAGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNK
DQGLKYFIDALDQGDCPTRTAILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPDTLFKDE
LESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLLGSQNLEKVGMTPEAPYPTTLQNKDGDPV
CIVQAWQYSYVVGELDITFDSQGRVKNCQGTPHILIGDDFKPKLTSAPALTHDQQLNIAKQLHLLAPEITVIEPDSRTSQ
ILSPYRDMKEKFRQTIVATAQEILCLRRVPGTQRDINRSSLGNVCNQDERVNRYGGDIQQLVAEAFLQQGKTYFSAQLSI
LNGGGVRTDVEQGPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVITLNNTGSYPYTAGLRWSVDFNQPKGQRI
SNIELKDSSGEYSLLMMDQTYRVVTLDFLANGSDYYHTLATIRNERRIDVGLDYAEAFMKYLEADGLSQPRALFRLPVSN
YSTQYFIDRPL
>Mature_651_residues
MLSKKLTTLQISLFNISNMLTPIALMFAISMGMSGCKEHHDSGSSTTVIPPENSASDDSSLKIIHINDHHSHLDEERMEF
DLNTGSTSGTYSVSRGGFARVSALFNQLAMGHGAILKLHAGDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNK
DQGLKYFIDALDQGDCPTRTAILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPDTLFKDE
LESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLLGSQNLEKVGMTPEAPYPTTLQNKDGDPV
CIVQAWQYSYVVGELDITFDSQGRVKNCQGTPHILIGDDFKPKLTSAPALTHDQQLNIAKQLHLLAPEITVIEPDSRTSQ
ILSPYRDMKEKFRQTIVATAQEILCLRRVPGTQRDINRSSLGNVCNQDERVNRYGGDIQQLVAEAFLQQGKTYFSAQLSI
LNGGGVRTDVEQGPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVITLNNTGSYPYTAGLRWSVDFNQPKGQRI
SNIELKDSSGEYSLLMMDQTYRVVTLDFLANGSDYYHTLATIRNERRIDVGLDYAEAFMKYLEADGLSQPRALFRLPVSN
YSTQYFIDRPL

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=560, Percent_Identity=29.1071428571429, Blast_Score=166, Evalue=5e-41,
Organism=Escherichia coli, GI1786687, Length=592, Percent_Identity=24.4932432432432, Blast_Score=108, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24641187, Length=552, Percent_Identity=27.3550724637681, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI19922446, Length=561, Percent_Identity=26.5597147950089, Blast_Score=176, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24654424, Length=561, Percent_Identity=26.5597147950089, Blast_Score=176, Evalue=5e-44,
Organism=Drosophila melanogaster, GI221329836, Length=576, Percent_Identity=26.2152777777778, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28573524, Length=586, Percent_Identity=26.4505119453925, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19922444, Length=563, Percent_Identity=25.2220248667851, Blast_Score=162, Evalue=8e-40,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843
- InterPro:   IPR006420 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 72010; Mature: 72010

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00785 5_NUCLEOTIDASE_1 ; PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKKLTTLQISLFNISNMLTPIALMFAISMGMSGCKEHHDSGSSTTVIPPENSASDDSS
CCCCCEEEEEEEEECHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEECCCCCCCCCCC
LKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALFNQLAMGHGAILKLHA
EEEEEECCCHHHCCCHHHEEECCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEC
GDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALDQGDCPTRT
CCCCCCCEEEEEECCCCCHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHCCCCCCCCE
AILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPDTLFKDE
EEEEECCCCCCCCCCCHHHCCCHHEEEEECCCEEEEEEEEEEHHCCCCCCCCCCCHHHHH
LESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLLGSQNLEKV
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCCEEEECCCCHHHC
GMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTPHILIGDDF
CCCCCCCCCCCCCCCCCCCEEEEEEECEEEEEEEEEEEECCCCCEECCCCCCEEEECCCC
KPKLTSAPALTHDQQLNIAKQLHLLAPEITVIEPDSRTSQILSPYRDMKEKFRQTIVATA
CCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
QEILCLRRVPGTQRDINRSSLGNVCNQDERVNRYGGDIQQLVAEAFLQQGKTYFSAQLSI
HHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEEE
LNGGGVRTDVEQGPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVITLNNTGSY
EECCCCEECCCCCCCCHHHHHHHCCCCCEEEEEEECCCCEEHHHHHCCEEEEEECCCCCC
PYTAGLRWSVDFNQPKGQRISNIELKDSSGEYSLLMMDQTYRVVTLDFLANGSDYYHTLA
CEECCEEEEEECCCCCCCCEEEEEEECCCCCEEEEEEECCEEEEEEEEEECCCHHHHHHH
TIRNERRIDVGLDYAEAFMKYLEADGLSQPRALFRLPVSNYSTQYFIDRPL
HHCCCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEECCC
>Mature Secondary Structure
MLSKKLTTLQISLFNISNMLTPIALMFAISMGMSGCKEHHDSGSSTTVIPPENSASDDSS
CCCCCEEEEEEEEECHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEECCCCCCCCCCC
LKIIHINDHHSHLDEERMEFDLNTGSTSGTYSVSRGGFARVSALFNQLAMGHGAILKLHA
EEEEEECCCHHHCCCHHHEEECCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEC
GDATTGDLYYNLTKGKADADVMNMICFDAFTLGNHEFDNKDQGLKYFIDALDQGDCPTRT
CCCCCCCEEEEEECCCCCHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHCCCCCCCCE
AILSANVEFGPSSPLYQSTRIQKSTVIETQGQKIGLVGLTIAQKTKNASQPNPDTLFKDE
EEEEECCCCCCCCCCCHHHCCCHHEEEEECCCEEEEEEEEEEHHCCCCCCCCCCCHHHHH
LESAQQQIDLLRQAGINKIILQSHVGYEMDKYLATQLHGVDVIVGGDSHTLLGSQNLEKV
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCCEEEECCCCHHHC
GMTPEAPYPTTLQNKDGDPVCIVQAWQYSYVVGELDITFDSQGRVKNCQGTPHILIGDDF
CCCCCCCCCCCCCCCCCCCEEEEEEECEEEEEEEEEEEECCCCCEECCCCCCEEEECCCC
KPKLTSAPALTHDQQLNIAKQLHLLAPEITVIEPDSRTSQILSPYRDMKEKFRQTIVATA
CCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
QEILCLRRVPGTQRDINRSSLGNVCNQDERVNRYGGDIQQLVAEAFLQQGKTYFSAQLSI
HHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEEE
LNGGGVRTDVEQGPISVEKVYQVLPYNSTLVQLNMQGNEIKATLEDAVDAVITLNNTGSY
EECCCCEECCCCCCCCHHHHHHHCCCCCEEEEEEECCCCEEHHHHHCCEEEEEECCCCCC
PYTAGLRWSVDFNQPKGQRISNIELKDSSGEYSLLMMDQTYRVVTLDFLANGSDYYHTLA
CEECCEEEEEECCCCCCCCEEEEEEECCCCCEEEEEEECCEEEEEEEEEECCCHHHHHHH
TIRNERRIDVGLDYAEAFMKYLEADGLSQPRALFRLPVSNYSTQYFIDRPL
HHCCCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]