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The map label for this gene is engA [H]

Identifier: 161349970

GI number: 161349970

Start: 556549

End: 557958

Strand: Direct

Name: engA [H]

Synonym: ACIAD0565

Alternate gene names: 161349970

Gene position: 556549-557958 (Clockwise)

Preceding gene: 50083800

Following gene: 50083802

Centisome position: 15.47

GC content: 46.17

Gene sequence:

>1410_bases
ATGAAACCCGTTATTGCGCTCATTGGTCGTCCGAACGTCGGAAAATCAACATTGTTTAACCAGATTACCAAGAGTCGTGA
TGCACTCGTGGCTGATTTTGCAGGGCTTACCCGTGACCGTAAGTATGGTGATGCGGTTTACCAAAATAAATCATTTATTG
TGGTTGATACTGGTGGTATTGGTGAGGGTGAAGCGGGCATTGACGCTTACATGGCTGAACAATCTAAAACAGCCATTCAT
GAAGCAGACATCATTATTTTTGTGGTTGATGCACGTGCAGGCTTGCTGGCATCGGATGAACAGATCGCGCGTGAAATCCG
TAGCTTAGGTAAAAAAGTCTACCTCGTGGCCAACAAAGTAGACGGTGTTCATGCAGAAGCTGCTGTGGTGGAATTTTACA
AGCTTGGCTTTGGTGAGCCGTTACATGTAGCGGCGAGTCATGGTCGTGGCGTGGCGCAAATGCTTGAAGATGTGCTGGTA
GATGTACCAGAAGATGAAAATCCTGAAGACCACGATAAAGCTACAGGCCTGAGACTGGCAATTATTGGTCGTCCAAATGT
GGGTAAATCAACCTTAGTCAATCGCCTGTTGGGCGAAGAACGTGTGGTGGCGTTTGACCAGCCAGGCACAACGCGTGACT
CGATTTATATTCCATTTGAGCGTGATGGGCGTCAATACACGCTGATCGATACTGCGGGTGTGCGTCGTAAAGGTAAAGTC
GATGAAATGATTGAGAAATTCTCGGTCGTTAAGACGCTACAAGCCATGAAAGATGCACATGTGGTCGTGGTGGTGGTCGA
TGCGCGTGAAGGAATTGTTGAGCAAGACTTGCACTTGATCGGTTATGCACTCGAAGCTGGCCGTGCCATGGTGATCGCCA
TTAATAAATGGGACAACATGACCGAGTATGATCGTAAACAATGTAAACTTGATGTTGAACGTCGCTTTGACTTTATTCCT
TGGGCGAAGATTCACTTGATTTCTGCGCTGCATGGTACGGGTGTAGGTGAGCTTTATCCGTCCATTCATCGTGCATATGA
GTCGGCTAATCTCAAAGTTTCACCAGCCAAGCTGACCCAGATTTTAAATGATGCAACAGAGGCGCATCAGCCTCCAATGA
TCAGTGGTCGTCGTATCAAAATGCGTTATGCGCATATGGGTGGACAAAATCCACCAACGATTGTGATTCATGGCAATAAG
GTTGATAAAACGCCAGCGGATTACCGCCGTTACCTCGAAAATGTATTCCGTAAAGTCTATAAGCTTGAAGGTACGCCTGT
ACGTATCGACTTTAAAACGTCTGAAAATCCATTTGAAGGTCGTAAGTCTCAAGTCGATGAGCGTGTGGCTGCACGTCGTC
GTCGTTATGTGCAAAAATTTAAGAAAGCAGAGAAAAAGTTTAAGCGTTAA

Upstream 100 bases:

>100_bases
CCGTATTTTTATTTGGGCCTCTGGCCTTTTATCTTCCTTAAATTTTTCGTTTCTGATGCAGATGCCATGAGAGATGGCAG
ATCTTGAAAAAGGTTACTCT

Downstream 100 bases:

>100_bases
TTACCAAATTGCTAAGCCCCGAAAATGTTCGGGGCTTTTTTATACACTGTATTTATTTTTATTAAATAATATCTTAAAGA
AAATAAAACGTAATTTTTTG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MKPVIALIGRPNVGKSTLFNQITKSRDALVADFAGLTRDRKYGDAVYQNKSFIVVDTGGIGEGEAGIDAYMAEQSKTAIH
EADIIIFVVDARAGLLASDEQIAREIRSLGKKVYLVANKVDGVHAEAAVVEFYKLGFGEPLHVAASHGRGVAQMLEDVLV
DVPEDENPEDHDKATGLRLAIIGRPNVGKSTLVNRLLGEERVVAFDQPGTTRDSIYIPFERDGRQYTLIDTAGVRRKGKV
DEMIEKFSVVKTLQAMKDAHVVVVVVDAREGIVEQDLHLIGYALEAGRAMVIAINKWDNMTEYDRKQCKLDVERRFDFIP
WAKIHLISALHGTGVGELYPSIHRAYESANLKVSPAKLTQILNDATEAHQPPMISGRRIKMRYAHMGGQNPPTIVIHGNK
VDKTPADYRRYLENVFRKVYKLEGTPVRIDFKTSENPFEGRKSQVDERVAARRRRYVQKFKKAEKKFKR

Sequences:

>Translated_469_residues
MKPVIALIGRPNVGKSTLFNQITKSRDALVADFAGLTRDRKYGDAVYQNKSFIVVDTGGIGEGEAGIDAYMAEQSKTAIH
EADIIIFVVDARAGLLASDEQIAREIRSLGKKVYLVANKVDGVHAEAAVVEFYKLGFGEPLHVAASHGRGVAQMLEDVLV
DVPEDENPEDHDKATGLRLAIIGRPNVGKSTLVNRLLGEERVVAFDQPGTTRDSIYIPFERDGRQYTLIDTAGVRRKGKV
DEMIEKFSVVKTLQAMKDAHVVVVVVDAREGIVEQDLHLIGYALEAGRAMVIAINKWDNMTEYDRKQCKLDVERRFDFIP
WAKIHLISALHGTGVGELYPSIHRAYESANLKVSPAKLTQILNDATEAHQPPMISGRRIKMRYAHMGGQNPPTIVIHGNK
VDKTPADYRRYLENVFRKVYKLEGTPVRIDFKTSENPFEGRKSQVDERVAARRRRYVQKFKKAEKKFKR
>Mature_469_residues
MKPVIALIGRPNVGKSTLFNQITKSRDALVADFAGLTRDRKYGDAVYQNKSFIVVDTGGIGEGEAGIDAYMAEQSKTAIH
EADIIIFVVDARAGLLASDEQIAREIRSLGKKVYLVANKVDGVHAEAAVVEFYKLGFGEPLHVAASHGRGVAQMLEDVLV
DVPEDENPEDHDKATGLRLAIIGRPNVGKSTLVNRLLGEERVVAFDQPGTTRDSIYIPFERDGRQYTLIDTAGVRRKGKV
DEMIEKFSVVKTLQAMKDAHVVVVVVDAREGIVEQDLHLIGYALEAGRAMVIAINKWDNMTEYDRKQCKLDVERRFDFIP
WAKIHLISALHGTGVGELYPSIHRAYESANLKVSPAKLTQILNDATEAHQPPMISGRRIKMRYAHMGGQNPPTIVIHGNK
VDKTPADYRRYLENVFRKVYKLEGTPVRIDFKTSENPFEGRKSQVDERVAARRRRYVQKFKKAEKKFKR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=488, Percent_Identity=53.0737704918033, Blast_Score=537, Evalue=1e-154,
Organism=Escherichia coli, GI1788919, Length=247, Percent_Identity=27.5303643724696, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=36.9565217391304, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=132, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=210, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 52517; Mature: 52517

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVIALIGRPNVGKSTLFNQITKSRDALVADFAGLTRDRKYGDAVYQNKSFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCHHHHCCCCEEEEECCCC
GEGEAGIDAYMAEQSKTAIHEADIIIFVVDARAGLLASDEQIAREIRSLGKKVYLVANKV
CCCCCCHHHHHHHHHHHHHEECCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECC
DGVHAEAAVVEFYKLGFGEPLHVAASHGRGVAQMLEDVLVDVPEDENPEDHDKATGLRLA
CCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCEEEE
IIGRPNVGKSTLVNRLLGEERVVAFDQPGTTRDSIYIPFERDGRQYTLIDTAGVRRKGKV
EEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCH
DEMIEKFSVVKTLQAMKDAHVVVVVVDAREGIVEQDLHLIGYALEAGRAMVIAINKWDNM
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCC
TEYDRKQCKLDVERRFDFIPWAKIHLISALHGTGVGELYPSIHRAYESANLKVSPAKLTQ
CHHHHHHHCEEHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEECHHHHHH
ILNDATEAHQPPMISGRRIKMRYAHMGGQNPPTIVIHGNKVDKTPADYRRYLENVFRKVY
HHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
KLEGTPVRIDFKTSENPFEGRKSQVDERVAARRRRYVQKFKKAEKKFKR
HCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPVIALIGRPNVGKSTLFNQITKSRDALVADFAGLTRDRKYGDAVYQNKSFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCHHHHCCCCEEEEECCCC
GEGEAGIDAYMAEQSKTAIHEADIIIFVVDARAGLLASDEQIAREIRSLGKKVYLVANKV
CCCCCCHHHHHHHHHHHHHEECCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECC
DGVHAEAAVVEFYKLGFGEPLHVAASHGRGVAQMLEDVLVDVPEDENPEDHDKATGLRLA
CCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCEEEE
IIGRPNVGKSTLVNRLLGEERVVAFDQPGTTRDSIYIPFERDGRQYTLIDTAGVRRKGKV
EEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCH
DEMIEKFSVVKTLQAMKDAHVVVVVVDAREGIVEQDLHLIGYALEAGRAMVIAINKWDNM
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCC
TEYDRKQCKLDVERRFDFIPWAKIHLISALHGTGVGELYPSIHRAYESANLKVSPAKLTQ
CHHHHHHHCEEHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEECHHHHHH
ILNDATEAHQPPMISGRRIKMRYAHMGGQNPPTIVIHGNKVDKTPADYRRYLENVFRKVY
HHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
KLEGTPVRIDFKTSENPFEGRKSQVDERVAARRRRYVQKFKKAEKKFKR
HCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA