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The map label for this gene is ydhC [C]

Identifier: 49481599

GI number: 49481599

Start: 3302033

End: 3303232

Strand: Reverse

Name: ydhC [C]

Synonym: BT9727_3235

Alternate gene names: 49481599

Gene position: 3303232-3302033 (Counterclockwise)

Preceding gene: 49478245

Following gene: 49478243

Centisome position: 63.07

GC content: 34.36

Gene sequence:

>1200_bases
ATGAAAAAAGTCTCAGTACCATCACTTTTATTAATGATTATTCTTGTCGCATTTCCGCAAATTAGTGAAACGATCTACAC
ACCGTCTTTACCAGACATTTCAAAGGCGTTGCACGTAAGTAATAATGAGGTACAGTTAACACTTAGTGTGTATTTTGCTG
GATTTGCTTTCGGTGTATTTTTTATTGGATGGCTATCGGATATAATTGGCCGTCGTCCGGCAATGTTATTTGGAATTGTT
GTATATGGCATTGGGAGTTTCTTATGCTTTATTGCAAATTCCATTGAAGTTTTATTAGTAAGTCGTTTTATTCAAGCATT
TGGAGCAAGTGCAGGATCAGTTGTGACGCANACGATTCTTCGTGAAAGTGTAGAAGGGCATAAGAGGCATGTTATGTTTG
CTCAAATCTCGGCAGTCATTGCTTTTACACCAGCGATAGGGCCATTAATTGGTGGATTTCTTGATCAAATGTTTGGATTT
AAAATAGTATTTTTAAGTTTAGTAGTTATGAGTGTCGGAATTTTTCTGTATACGTTTGTTTCTCTTCCAGAAACAAAAAC
GAGCTCAGTAACAAATAAAATAAATGTTTTTTCAGTATTGAAAAGATTAATTACAAATCCGAAAGTAGTAACATATGGGC
TATTAATTGGAGGTGCAAATGGTGTTTTATTTAGCTATTATGCAGAAGCACCGTTTATCTTTATTGAATACTTTCGATTA
TCGCCTAGTATGTATGGATTTTTAGGAATTGTTGTTGCTTCTGCTTCTATTATTGGAGCGAAAGTTTCAAAACGATTGCT
TGCAACTTATAAACCAGAGAAAATTATATATATCGGTTGTCTTGTAATGGTAGTTGGAGCAGTCGCTTTATCTCTTATTA
CTTCAGTTGGATCAAATCCAAACATAATATATATGGTCGGATTTTTAGTAGCGATGTTTATATTGCTATTAGGAATTGGA
GTAGCATTACCTAACTGTTTAAGTTTAGCATTAGTAGATTTTCAAGATGTCATTGGTACAGCGGGTGCATTGTTTAGCCT
AGGGTACTATGTAATTGTAACGATAACAATTTGGGGAATGAGTCAACTTCATACGGGCTCGTTACTGGTGATGCCACTTT
ATTTTCTAGCTATAGTAGTTATCATGATGGTGTTTACTAAAGTGTTTGTTTTAGGTAAACAAACTTCAAAAACGATTTAA

Upstream 100 bases:

>100_bases
TTGTTTTATGAGCGAATTTCTATAATGGCCCCTCCTGTTCCGTAGCTAAGGAAAGTCTTTTTATTTCTGAGATTTTCAAA
GTTATAGGAGGGTATGAAAA

Downstream 100 bases:

>100_bases
ATATGAAATGGTAAAAGAGTCTCATTTTTTAATGAGACTCTTTTATATTTTATGAAAATGATTAGTGGATATACGAATAA
AAATTAAAGGTATTGTTGAT

Product: Bcr/CflA subfamily drug resistance transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFAFGVFFIGWLSDIIGRRPAMLFGIV
VYGIGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTXTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTSSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFRL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMVVGAVALSLITSVGSNPNIIYMVGFLVAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTITIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFVLGKQTSKTI

Sequences:

>Translated_399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFAFGVFFIGWLSDIIGRRPAMLFGIV
VYGIGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTXTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTSSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFRL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMVVGAVALSLITSVGSNPNIIYMVGFLVAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTITIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFVLGKQTSKTI
>Mature_399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFAFGVFFIGWLSDIIGRRPAMLFGIV
VYGIGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTXTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTSSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFRL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMVVGAVALSLITSVGSNPNIIYMVGFLVAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTITIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFVLGKQTSKTI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=324, Percent_Identity=25.6172839506173, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788509, Length=230, Percent_Identity=27.3913043478261, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790146, Length=191, Percent_Identity=26.7015706806283, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082312, Length=326, Percent_Identity=26.0736196319018, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787065, Length=340, Percent_Identity=24.4117647058824, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790794, Length=384, Percent_Identity=23.1770833333333, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324264, Length=170, Percent_Identity=31.1764705882353, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43118; Mature: 43118

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA