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The map label for this gene is czcD

Identifier: 49481497

GI number: 49481497

Start: 4206722

End: 4207615

Strand: Reverse

Name: czcD

Synonym: BT9727_4143

Alternate gene names: 49481497

Gene position: 4207615-4206722 (Counterclockwise)

Preceding gene: 49481498

Following gene: 49481496

Centisome position: 80.33

GC content: 38.7

Gene sequence:

>894_bases
ATGGAAAAAGATGAACGTTTTAAACAGGCCGAGTTTGGTGCTATTGTCGGGATCGTTGGTAATATTATATTAGCGATTAT
AAAGGCGGTAATTGGTTATATTGGGAACAGTAAAGCGCTATTAGCGGATGCCGTGCATTCTGCATCGGATGTAATTGGTT
CGCTAGCTGTACTGTTTGGATTGCGAGCGGCGAAGCAACCGCCCGATGAAGATCATCCGTATGGTCATGGTAAAGCGGAA
TCGATTTCAGCGATTATTGTTGCAGTATTATTATTTATTGTGGGAATTGAGATAGCGATTTCGTCTATAAAAGCTTTTTC
GCAAGAACTAGAACCACCGAAAGGGATTACGATTTTTGCTGTCGTTCTTTCGATTGTTGTAAAAGAAGGGATGTTTCAAT
ATAAATTCCGATTAGGGAAAAGGGTAAATAGTGATGCAATTATTGCAAATGCATATGAGCACCGTTCAGATGTATTTTCT
TCAATTGCAGCCTTAATCGGTATTTGTGCAGCGATTATCGGTGGAAAGTTCGGGTTAGATTGGCTTGTATACGCCGATCC
AATTGCGGGATTATTTGTTTCACTTCTTGTTGCAAAAATGGCATGGAGTATTGGGGCAGAAGCGATTCATGCAACGCTTG
ATCATGTTCTTCATGAGGAAGATGTTATTCCGCTTAGAGAAGCAGTACTTCAAATAGATGGTGTAAAAAAAATTGGTTCT
TTATACGCAAGGGAACATGGTCATTACGTTATTGTTGATATTAAAGTTTCTGTAGATCCATACATTACTGTAGAAGAAGG
GCATCGCATTGGAAAGCATGTGAAAGAAACGCTTATGAAACAAGATAACGTACAAAATGTGTTTGTACATATAAATCCGT
ATTCTCCAAATTAA

Upstream 100 bases:

>100_bases
AGATAGCAACTTTGAAATGATAAAATGGAAGAAAGTGGTGATGTTATCGCTGTTTTTGTTACAATAAAAAGATAGGTTAA
GAAAAGAAGGGATTTTAATT

Downstream 100 bases:

>100_bases
ACATTATTAATATTTTAGTATATAGATATTGCATCGTAGTTTGCATTATATTGTCACCCCTTAATCTGTCTTGTATAATG
AACAGGTTAAGGGGTGATTT

Product: cation efflux family protein; cobalt-zinc-cadmium resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MEKDERFKQAEFGAIVGIVGNIILAIIKAVIGYIGNSKALLADAVHSASDVIGSLAVLFGLRAAKQPPDEDHPYGHGKAE
SISAIIVAVLLFIVGIEIAISSIKAFSQELEPPKGITIFAVVLSIVVKEGMFQYKFRLGKRVNSDAIIANAYEHRSDVFS
SIAALIGICAAIIGGKFGLDWLVYADPIAGLFVSLLVAKMAWSIGAEAIHATLDHVLHEEDVIPLREAVLQIDGVKKIGS
LYAREHGHYVIVDIKVSVDPYITVEEGHRIGKHVKETLMKQDNVQNVFVHINPYSPN

Sequences:

>Translated_297_residues
MEKDERFKQAEFGAIVGIVGNIILAIIKAVIGYIGNSKALLADAVHSASDVIGSLAVLFGLRAAKQPPDEDHPYGHGKAE
SISAIIVAVLLFIVGIEIAISSIKAFSQELEPPKGITIFAVVLSIVVKEGMFQYKFRLGKRVNSDAIIANAYEHRSDVFS
SIAALIGICAAIIGGKFGLDWLVYADPIAGLFVSLLVAKMAWSIGAEAIHATLDHVLHEEDVIPLREAVLQIDGVKKIGS
LYAREHGHYVIVDIKVSVDPYITVEEGHRIGKHVKETLMKQDNVQNVFVHINPYSPN
>Mature_297_residues
MEKDERFKQAEFGAIVGIVGNIILAIIKAVIGYIGNSKALLADAVHSASDVIGSLAVLFGLRAAKQPPDEDHPYGHGKAE
SISAIIVAVLLFIVGIEIAISSIKAFSQELEPPKGITIFAVVLSIVVKEGMFQYKFRLGKRVNSDAIIANAYEHRSDVFS
SIAALIGICAAIIGGKFGLDWLVYADPIAGLFVSLLVAKMAWSIGAEAIHATLDHVLHEEDVIPLREAVLQIDGVKKIGS
LYAREHGHYVIVDIKVSVDPYITVEEGHRIGKHVKETLMKQDNVQNVFVHINPYSPN

Specific function: Unknown

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family [H]

Homologues:

Organism=Escherichia coli, GI1790349, Length=284, Percent_Identity=26.056338028169, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI115533508, Length=279, Percent_Identity=21.8637992831541, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI115533506, Length=279, Percent_Identity=21.8637992831541, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72000060, Length=304, Percent_Identity=22.3684210526316, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000062, Length=304, Percent_Identity=22.3684210526316, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325032, Length=254, Percent_Identity=31.1023622047244, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323831, Length=247, Percent_Identity=28.7449392712551, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 32165; Mature: 32165

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDERFKQAEFGAIVGIVGNIILAIIKAVIGYIGNSKALLADAVHSASDVIGSLAVLFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LRAAKQPPDEDHPYGHGKAESISAIIVAVLLFIVGIEIAISSIKAFSQELEPPKGITIFA
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VVLSIVVKEGMFQYKFRLGKRVNSDAIIANAYEHRSDVFSSIAALIGICAAIIGGKFGLD
HHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
WLVYADPIAGLFVSLLVAKMAWSIGAEAIHATLDHVLHEEDVIPLREAVLQIDGVKKIGS
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LYAREHGHYVIVDIKVSVDPYITVEEGHRIGKHVKETLMKQDNVQNVFVHINPYSPN
HHHHCCCCEEEEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MEKDERFKQAEFGAIVGIVGNIILAIIKAVIGYIGNSKALLADAVHSASDVIGSLAVLFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LRAAKQPPDEDHPYGHGKAESISAIIVAVLLFIVGIEIAISSIKAFSQELEPPKGITIFA
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VVLSIVVKEGMFQYKFRLGKRVNSDAIIANAYEHRSDVFSSIAALIGICAAIIGGKFGLD
HHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
WLVYADPIAGLFVSLLVAKMAWSIGAEAIHATLDHVLHEEDVIPLREAVLQIDGVKKIGS
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LYAREHGHYVIVDIKVSVDPYITVEEGHRIGKHVKETLMKQDNVQNVFVHINPYSPN
HHHHCCCCEEEEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]