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The map label for this gene is fhuB

Identifier: 49481475

GI number: 49481475

Start: 4341165

End: 4342148

Strand: Reverse

Name: fhuB

Synonym: BT9727_4279

Alternate gene names: 49481475

Gene position: 4342148-4341165 (Counterclockwise)

Preceding gene: 49478683

Following gene: 49481788

Centisome position: 82.9

GC content: 37.09

Gene sequence:

>984_bases
ATGAATAAAAAAACTTGGAGTTTCCTCATTGTTACTGTATTGCTTATTGTTATGACGTCATTATCAGCGATGAAAGGGAG
TTTAGAAGTAGGTATTGTTGAACTTGTACAAGGGATATTTACAGGTGGAAATGAAGATGTTGAGGTCATTAAAGATTTAC
GTTTTCCGCGTATTATTATTGCGTTATTCACTGGAGCGGCTCTTGCTGTTTCTGGTGTGCTTTTTCAAGCTGTAATGAAA
AATCCACTTGCCGATGCTGGGGTAATCGGGATATCTTCAGGAGCAAGTTTTATGACACTTGTTATTATAACGTTGTTCCC
GCAATTCTTTTTCTGGACACCAGTATTTGCCTTTTTAGGTGGTGCGTTTGCGTGTTATCTCGTTTATGCATTTTCATGGA
AGTCAGGGTTAAGTCCACTTCGTATTATTTTAGTTGGTATAGCTATTAATGCGATGTTTACTGGATTAAATGAATCGTTC
ATTACGATTTGTGGATATTTCATTAAGAGTATTAAGCAAACGACGACTTCTAATATAACGATGAAGACGTGGGATGATGT
AGAAATAATGGTTACGTATGGAACAATTGGTTTGGTTCTTGCTCTGTTTGTAGGAGCTTGGTGTAATTTATTATCGCTAC
AAGATAAGACTGCGAAAAACTTAGGTTTGCACGTGACGAGAGTTCGTCTTATTATTTCTGCTATTGCAGTACTTTTAGCG
GCAGTATCAACAGCGATTGCAGGTGTTATTGCTTTCGTAGGATTACTTGTTCCTCACATTTCAAGACAATTAGTCGGTTC
AGATCATAAAGTATTAATTCCTTTTTCTGCTCTTGCAGGAGCGTTATTAATTTTGACGGCTGATACGATTGGAAGGTTAA
TTGTGCCACCTAATGAAATTCCAGCAGCAACGATTATGGCAGTTATTGGTGGCCCATTCTTAATATTCTTGCTTAGAAAG
AGTGATAAAGTTCATGGAAATTAA

Upstream 100 bases:

>100_bases
TTTATTTGGAACGACAGGAAATTTAGCAGCAATTGAAGCGTTAGATGAATTGAAAAAAATGATGTATCCGTGATGCATTT
TCATATAAAGGAAGAGTGAA

Downstream 100 bases:

>100_bases
AAATGTAACCTTTTCGTATGATAATGTAACGGATCGATTAAAGTCGGTTAGTAGTGAAATAGAAATTGGTAAAGTTACAA
CAATTATTGGTCCAAATGGT

Product: iron compound ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron-regulated surface determinant protein F; Staphylococcal iron-regulated protein G [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNKKTWSFLIVTVLLIVMTSLSAMKGSLEVGIVELVQGIFTGGNEDVEVIKDLRFPRIIIALFTGAALAVSGVLFQAVMK
NPLADAGVIGISSGASFMTLVIITLFPQFFFWTPVFAFLGGAFACYLVYAFSWKSGLSPLRIILVGIAINAMFTGLNESF
ITICGYFIKSIKQTTTSNITMKTWDDVEIMVTYGTIGLVLALFVGAWCNLLSLQDKTAKNLGLHVTRVRLIISAIAVLLA
AVSTAIAGVIAFVGLLVPHISRQLVGSDHKVLIPFSALAGALLILTADTIGRLIVPPNEIPAATIMAVIGGPFLIFLLRK
SDKVHGN

Sequences:

>Translated_327_residues
MNKKTWSFLIVTVLLIVMTSLSAMKGSLEVGIVELVQGIFTGGNEDVEVIKDLRFPRIIIALFTGAALAVSGVLFQAVMK
NPLADAGVIGISSGASFMTLVIITLFPQFFFWTPVFAFLGGAFACYLVYAFSWKSGLSPLRIILVGIAINAMFTGLNESF
ITICGYFIKSIKQTTTSNITMKTWDDVEIMVTYGTIGLVLALFVGAWCNLLSLQDKTAKNLGLHVTRVRLIISAIAVLLA
AVSTAIAGVIAFVGLLVPHISRQLVGSDHKVLIPFSALAGALLILTADTIGRLIVPPNEIPAATIMAVIGGPFLIFLLRK
SDKVHGN
>Mature_327_residues
MNKKTWSFLIVTVLLIVMTSLSAMKGSLEVGIVELVQGIFTGGNEDVEVIKDLRFPRIIIALFTGAALAVSGVLFQAVMK
NPLADAGVIGISSGASFMTLVIITLFPQFFFWTPVFAFLGGAFACYLVYAFSWKSGLSPLRIILVGIAINAMFTGLNESF
ITICGYFIKSIKQTTTSNITMKTWDDVEIMVTYGTIGLVLALFVGAWCNLLSLQDKTAKNLGLHVTRVRLIISAIAVLLA
AVSTAIAGVIAFVGLLVPHISRQLVGSDHKVLIPFSALAGALLILTADTIGRLIVPPNEIPAATIMAVIGGPFLIFLLRK
SDKVHGN

Specific function: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=282, Percent_Identity=32.9787234042553, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1790741, Length=281, Percent_Identity=31.6725978647687, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786805, Length=284, Percent_Identity=35.2112676056338, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786347, Length=282, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786804, Length=327, Percent_Identity=30.2752293577982, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788004, Length=282, Percent_Identity=32.2695035460993, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34978; Mature: 34978

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKTWSFLIVTVLLIVMTSLSAMKGSLEVGIVELVQGIFTGGNEDVEVIKDLRFPRIII
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHH
ALFTGAALAVSGVLFQAVMKNPLADAGVIGISSGASFMTLVIITLFPQFFFWTPVFAFLG
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GAFACYLVYAFSWKSGLSPLRIILVGIAINAMFTGLNESFITICGYFIKSIKQTTTSNIT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCE
MKTWDDVEIMVTYGTIGLVLALFVGAWCNLLSLQDKTAKNLGLHVTRVRLIISAIAVLLA
EEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHH
AVSTAIAGVIAFVGLLVPHISRQLVGSDHKVLIPFSALAGALLILTADTIGRLIVPPNEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHEEHHHHCCEEECCCCC
PAATIMAVIGGPFLIFLLRKSDKVHGN
CHHHHHHHHCCHHHEEEECCCCCCCCC
>Mature Secondary Structure
MNKKTWSFLIVTVLLIVMTSLSAMKGSLEVGIVELVQGIFTGGNEDVEVIKDLRFPRIII
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHH
ALFTGAALAVSGVLFQAVMKNPLADAGVIGISSGASFMTLVIITLFPQFFFWTPVFAFLG
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GAFACYLVYAFSWKSGLSPLRIILVGIAINAMFTGLNESFITICGYFIKSIKQTTTSNIT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCE
MKTWDDVEIMVTYGTIGLVLALFVGAWCNLLSLQDKTAKNLGLHVTRVRLIISAIAVLLA
EEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHH
AVSTAIAGVIAFVGLLVPHISRQLVGSDHKVLIPFSALAGALLILTADTIGRLIVPPNEI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHEEHHHHCCEEECCCCC
PAATIMAVIGGPFLIFLLRKSDKVHGN
CHHHHHHHHCCHHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA