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The map label for this gene is tetR

Identifier: 49481472

GI number: 49481472

Start: 4322199

End: 4322786

Strand: Reverse

Name: tetR

Synonym: BT9727_4260

Alternate gene names: 49481472

Gene position: 4322786-4322199 (Counterclockwise)

Preceding gene: 49481470

Following gene: 49481480

Centisome position: 82.53

GC content: 37.41

Gene sequence:

>588_bases
GTGAAGAAAAATAGACCGAAATACAATCAAATTATTGATGCGGCAGTCATTGTGATTGCGGAGAATGGGTACCATCAAGC
GCAAGTTTCTAAAATAGCAAAGCAAGCTGGGGTAGCTGATGGCACGATTTATTTATATTTTAAAAATAAAGAAGATATAT
TAATATCCTTATTCCAAGAGAAGATGGGAGAATTTGTCGAAACAATTCGTCAAAAAACAGCAGGAATTGAAAGCGCTGTA
TCGAAGTTATTCATGTTGGTAGAAACGCACTTCTTGCTGTTGTCGCAAAATGATCCTCTTGCTATCGTTACGCAATTAGA
GCTAAGACAGTCCAATCAAGACTTACGCCTGAAGATAAATGAAGTATTAAAAGGCTACTTACAAGTTATTGATGAGATTT
TAGAGACAGGTATAAAGCAAGGTGAATTCCAAGCGGATTTAAATGTTCGCGTGGCAAGACAAATGATCTTTGGAACAGTA
GATGAAGTTGTGACCAATTGGGTAATGAGCGATCATAAGTATGATCTGGTCGCACTTTCAAAAACGGTACATGGGCTACT
TATTGCAGCTTGTGGTTATCGTCAATAA

Upstream 100 bases:

>100_bases
TTCTTTTTGAAAAAATGGGATTGACACTTTTCTAAATAGTCAGTATTATAAGAATATGAATGACTATTCATTCAGTCATC
TTCTTGAAGGGGACAGTAAA

Downstream 100 bases:

>100_bases
TGGGAGGGATCATGTTGAAATTCCTATCTGTAAGAGTTGAAGATCATATCGCGGTGGCTACGTTAAATCATGCGCCAGCT
AACGCGATGTCTTCACAAGT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKKNRPKYNQIIDAAVIVIAENGYHQAQVSKIAKQAGVADGTIYLYFKNKEDILISLFQEKMGEFVETIRQKTAGIESAV
SKLFMLVETHFLLLSQNDPLAIVTQLELRQSNQDLRLKINEVLKGYLQVIDEILETGIKQGEFQADLNVRVARQMIFGTV
DEVVTNWVMSDHKYDLVALSKTVHGLLIAACGYRQ

Sequences:

>Translated_195_residues
MKKNRPKYNQIIDAAVIVIAENGYHQAQVSKIAKQAGVADGTIYLYFKNKEDILISLFQEKMGEFVETIRQKTAGIESAV
SKLFMLVETHFLLLSQNDPLAIVTQLELRQSNQDLRLKINEVLKGYLQVIDEILETGIKQGEFQADLNVRVARQMIFGTV
DEVVTNWVMSDHKYDLVALSKTVHGLLIAACGYRQ
>Mature_195_residues
MKKNRPKYNQIIDAAVIVIAENGYHQAQVSKIAKQAGVADGTIYLYFKNKEDILISLFQEKMGEFVETIRQKTAGIESAV
SKLFMLVETHFLLLSQNDPLAIVTQLELRQSNQDLRLKINEVLKGYLQVIDEILETGIKQGEFQADLNVRVARQMIFGTV
DEVVTNWVMSDHKYDLVALSKTVHGLLIAACGYRQ

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22058; Mature: 22058

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNRPKYNQIIDAAVIVIAENGYHQAQVSKIAKQAGVADGTIYLYFKNKEDILISLFQE
CCCCCCHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHH
KMGEFVETIRQKTAGIESAVSKLFMLVETHFLLLSQNDPLAIVTQLELRQSNQDLRLKIN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEHHHCCCCCCEEEHH
EVLKGYLQVIDEILETGIKQGEFQADLNVRVARQMIFGTVDEVVTNWVMSDHKYDLVALS
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
KTVHGLLIAACGYRQ
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKNRPKYNQIIDAAVIVIAENGYHQAQVSKIAKQAGVADGTIYLYFKNKEDILISLFQE
CCCCCCHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHH
KMGEFVETIRQKTAGIESAVSKLFMLVETHFLLLSQNDPLAIVTQLELRQSNQDLRLKIN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEHHHCCCCCCEEEHH
EVLKGYLQVIDEILETGIKQGEFQADLNVRVARQMIFGTVDEVVTNWVMSDHKYDLVALS
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
KTVHGLLIAACGYRQ
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]