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The map label for this gene is aroE

Identifier: 49481393

GI number: 49481393

Start: 4133688

End: 4134521

Strand: Reverse

Name: aroE

Synonym: BT9727_4070

Alternate gene names: 49481393

Gene position: 4134521-4133688 (Counterclockwise)

Preceding gene: 49481394

Following gene: 49478612

Centisome position: 78.94

GC content: 37.89

Gene sequence:

>834_bases
ATGAAACAATTATATGGTGTAATCGGAAATCCAATTGGACATTCATTATCACCCGTTATGCATAACGATGCATTTGAACA
CTTGAATATGGATGCCCATTACCATGCCTTTCTTGTTAAAGAGGAAGTGTTAGGGGAAGCAGTAAGAGGTTTAAAAGCGT
TAGGTATTTCAGGATTTAATGTAACAACTCCGCACAAGGTTGCGATTATGGATTATTTGGATGAGATTGACCCGCTAGCA
AAACAAATTGGTGCAGTAAATACGGTGGTTCATAAGGATGGAAAATTGATTGGCTACAATACAGATGGAATTGGTTTTGT
CCGAGCACTGCAATCCATTAGTAGTGAACCACTTCAAGAGAAACGTATTTTATTACTTGGCGCAGGCGGTGCTAGTCGAG
CTATTTATTTTTCACTTGCTGATGCAGGGGTGAAAGAGATTGATGTAGCTAATCGTACAGTAGATAAGGCGAAAGAACTT
ATTGCTGCATGTACGGCTACTGTTCATTCTGTTGCTTTATCATTAGAAAAAGCAACAAAAGAACAAGGGAGTTATGATAT
TATCATTCAGACGACAACGATAGGTATGCATCCACGCGTCGAACATACGCCGTTACAAATTTCTTCGTTGAAAAAGGGAA
CAATTGTATCAGATATAATTTATAATCCATTTGAAACGAAAATTTTATGTGAGGCGAAAGAGCAAGGTGCAATCATTCAA
AATGGTATTGATATGTTTGTTTATCAAGGAGCGCTTGCATTTGAAATGTGGACAGGTTGCGTACCGAATATCGAACGAAT
GAAACAATTAGTTATAAGAAAGCTTGGAGGCTAA

Upstream 100 bases:

>100_bases
GGTTACTGTGAACGAACCAGGAGCAAAAATTGTTGCACACGTACCAAAAGGAGTAAGTGTTTCATTACGTAAATCTTTAA
TTTAATATGGAGAGGGATTT

Downstream 100 bases:

>100_bases
CATATATGTTAACAGGAAAACAAAAAAGATTTTTACGTGCACAAGCACATCATTTAACACCAATTTTTCAAGTAGGAAAA
GGCGGAGTAAATGAAAATAT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKQLYGVIGNPIGHSLSPVMHNDAFEHLNMDAHYHAFLVKEEVLGEAVRGLKALGISGFNVTTPHKVAIMDYLDEIDPLA
KQIGAVNTVVHKDGKLIGYNTDGIGFVRALQSISSEPLQEKRILLLGAGGASRAIYFSLADAGVKEIDVANRTVDKAKEL
IAACTATVHSVALSLEKATKEQGSYDIIIQTTTIGMHPRVEHTPLQISSLKKGTIVSDIIYNPFETKILCEAKEQGAIIQ
NGIDMFVYQGALAFEMWTGCVPNIERMKQLVIRKLGG

Sequences:

>Translated_277_residues
MKQLYGVIGNPIGHSLSPVMHNDAFEHLNMDAHYHAFLVKEEVLGEAVRGLKALGISGFNVTTPHKVAIMDYLDEIDPLA
KQIGAVNTVVHKDGKLIGYNTDGIGFVRALQSISSEPLQEKRILLLGAGGASRAIYFSLADAGVKEIDVANRTVDKAKEL
IAACTATVHSVALSLEKATKEQGSYDIIIQTTTIGMHPRVEHTPLQISSLKKGTIVSDIIYNPFETKILCEAKEQGAIIQ
NGIDMFVYQGALAFEMWTGCVPNIERMKQLVIRKLGG
>Mature_277_residues
MKQLYGVIGNPIGHSLSPVMHNDAFEHLNMDAHYHAFLVKEEVLGEAVRGLKALGISGFNVTTPHKVAIMDYLDEIDPLA
KQIGAVNTVVHKDGKLIGYNTDGIGFVRALQSISSEPLQEKRILLLGAGGASRAIYFSLADAGVKEIDVANRTVDKAKEL
IAACTATVHSVALSLEKATKEQGSYDIIIQTTTIGMHPRVEHTPLQISSLKKGTIVSDIIYNPFETKILCEAKEQGAIIQ
NGIDMFVYQGALAFEMWTGCVPNIERMKQLVIRKLGG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=280, Percent_Identity=39.2857142857143, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789675, Length=272, Percent_Identity=34.1911764705882, Blast_Score=129, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320332, Length=275, Percent_Identity=33.4545454545455, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30123; Mature: 30123

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLYGVIGNPIGHSLSPVMHNDAFEHLNMDAHYHAFLVKEEVLGEAVRGLKALGISGFN
CCCHHHHHCCCCCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VTTPHKVAIMDYLDEIDPLAKQIGAVNTVVHKDGKLIGYNTDGIGFVRALQSISSEPLQE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCHHHHHHHHHHCCCCCCC
KRILLLGAGGASRAIYFSLADAGVKEIDVANRTVDKAKELIAACTATVHSVALSLEKATK
CEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQGSYDIIIQTTTIGMHPRVEHTPLQISSLKKGTIVSDIIYNPFETKILCEAKEQGAIIQ
CCCCEEEEEEEEEECCCCCCCCCCCHHHCCCCCCCHHHHHCCCCCCEEEEECHHCCCCHH
NGIDMFVYQGALAFEMWTGCVPNIERMKQLVIRKLGG
CCCEEEHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQLYGVIGNPIGHSLSPVMHNDAFEHLNMDAHYHAFLVKEEVLGEAVRGLKALGISGFN
CCCHHHHHCCCCCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VTTPHKVAIMDYLDEIDPLAKQIGAVNTVVHKDGKLIGYNTDGIGFVRALQSISSEPLQE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCHHHHHHHHHHCCCCCCC
KRILLLGAGGASRAIYFSLADAGVKEIDVANRTVDKAKELIAACTATVHSVALSLEKATK
CEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQGSYDIIIQTTTIGMHPRVEHTPLQISSLKKGTIVSDIIYNPFETKILCEAKEQGAIIQ
CCCCEEEEEEEEEECCCCCCCCCCCHHHCCCCCCCHHHHHCCCCCCEEEEECHHCCCCHH
NGIDMFVYQGALAFEMWTGCVPNIERMKQLVIRKLGG
CCCEEEHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA