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The map label for this gene is glpT

Identifier: 49481234

GI number: 49481234

Start: 4993222

End: 4994556

Strand: Reverse

Name: glpT

Synonym: BT9727_4940

Alternate gene names: 49481234

Gene position: 4994556-4993222 (Counterclockwise)

Preceding gene: 49480797

Following gene: 49481232

Centisome position: 95.36

GC content: 36.85

Gene sequence:

>1335_bases
ATGTTTAAATGGCTCAAGCCAGCACCTGCAATTGAACGTTTACCAGCGGATATGATCGACCGTGTATATCGATTACTACG
TATTCGCGTGTTAATCGGAATTTCAGTTGGATATGCTGCTTATTATTTAGTTCGTAGTAACTTTACGCTATCAAGTACGT
ACTTAGTACAAGAATATGGTTTTAGTACAGCTGAAATTGGTCTACTAGGTTCAGTAATGGCAATTGTTTATGGTTTTAGT
AAGTTCTTTATGGGGAATTTATCAGATAAAGCTTTCGCCCAGCGCTTTATCGCAGTCGGTTTATTTTTATCAGGGCTTGT
AAATATTTGCTTCGGTTTTGCATCTTCATTTGGGATGATTGTTACATTACTTGTCGTTAACGGTATTGTACAAGGTATGG
GAGCACCCCCTTGTAGTATTGTTATGACGAAATGGTTCTCGAAGAAAGAACGCGGTACGAAAACAGGTATTTGGAATATT
TCACATAACGTTGGTGGAATGCTTGTACCACCACTTGTCGGAATTGGTGTAGGTATTTTTGGTGAAAATCATTGGCAAGG
CGGCGTGTTTATTTTCCCAGCGATTATCGCAATGGTAATTGCAGTTCTTGTTTGGATTAATGCGAAGGATACACCGGAAT
CAGAAGGTCTTCCTCCAATTGATGAGTATCGTAATGACTATGAAAATCTTGAAAAAGCAGACAATGCTAACAAGATGTCA
CCAAAAGAAATTTTAATGAAGTATGTAGTGAAAAATAAATTTGTATGGTTCTTATGTATTGCAAATGCATTTGTATATTT
AATTCGTTTCGGTGTTATTAACTGGGTTCCACTTTATTTAACGACAGTTAAAGGTTTCTCAAAAAATGAAGCACACGCAG
CGTACACAATCTTTGAAGGTATGGCAATTCCAAGTTCATTAATCGTTGGTCTTTTAAGTGATAAATTATTTAAAGGAAAA
CGTATGCCATTATGTATCTTTAGTATGGTCGGAGTTGTTATTGGTACGTTTGTATATTGGCAAGCAACTAGCATACTTGT
TATAAGTATTGCAGTTTCTATTATTGGTTGTTTAATTTATGTACCACAGTTCTTAATCGGTTTAAGTGCAATGGAATTAG
TACCGAAATTTGCAGTAGGTACGACAGTTGGTATGTGTGGTCTGTTCGGTTATGTGGGCGGAAGTCTTGTAGCAAACGCA
GCAATTGGTGTTATTGTTGATCGTTCTGGCTGGGATGGTTGTTTTATCTTACTATTAACAGGTGCCATTTTATCAACAAT
CTTCTTGTTCATCGTTCAACGTGGACATGAGAGCAAAGCTTCTAAAGTAGCATAA

Upstream 100 bases:

>100_bases
CCGGTTAGAAGAACAAACCAAAATATATCAAATAGCGGAATAATCGAGATATGGAATAGACAACGTCTCTCTCAGAAGTG
AGAAAAGGAGACGAAAGAAT

Downstream 100 bases:

>100_bases
TATTTCATTTTAAAAAGCTATCCAGTTTTTATACTGGATAGCTTTTATATTTTTATACGAGGAAAATCAGTATGTAAAAT
TGAAGTTTAATATGTAAATA

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MFKWLKPAPAIERLPADMIDRVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLVQEYGFSTAEIGLLGSVMAIVYGFS
KFFMGNLSDKAFAQRFIAVGLFLSGLVNICFGFASSFGMIVTLLVVNGIVQGMGAPPCSIVMTKWFSKKERGTKTGIWNI
SHNVGGMLVPPLVGIGVGIFGENHWQGGVFIFPAIIAMVIAVLVWINAKDTPESEGLPPIDEYRNDYENLEKADNANKMS
PKEILMKYVVKNKFVWFLCIANAFVYLIRFGVINWVPLYLTTVKGFSKNEAHAAYTIFEGMAIPSSLIVGLLSDKLFKGK
RMPLCIFSMVGVVIGTFVYWQATSILVISIAVSIIGCLIYVPQFLIGLSAMELVPKFAVGTTVGMCGLFGYVGGSLVANA
AIGVIVDRSGWDGCFILLLTGAILSTIFLFIVQRGHESKASKVA

Sequences:

>Translated_444_residues
MFKWLKPAPAIERLPADMIDRVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLVQEYGFSTAEIGLLGSVMAIVYGFS
KFFMGNLSDKAFAQRFIAVGLFLSGLVNICFGFASSFGMIVTLLVVNGIVQGMGAPPCSIVMTKWFSKKERGTKTGIWNI
SHNVGGMLVPPLVGIGVGIFGENHWQGGVFIFPAIIAMVIAVLVWINAKDTPESEGLPPIDEYRNDYENLEKADNANKMS
PKEILMKYVVKNKFVWFLCIANAFVYLIRFGVINWVPLYLTTVKGFSKNEAHAAYTIFEGMAIPSSLIVGLLSDKLFKGK
RMPLCIFSMVGVVIGTFVYWQATSILVISIAVSIIGCLIYVPQFLIGLSAMELVPKFAVGTTVGMCGLFGYVGGSLVANA
AIGVIVDRSGWDGCFILLLTGAILSTIFLFIVQRGHESKASKVA
>Mature_444_residues
MFKWLKPAPAIERLPADMIDRVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLVQEYGFSTAEIGLLGSVMAIVYGFS
KFFMGNLSDKAFAQRFIAVGLFLSGLVNICFGFASSFGMIVTLLVVNGIVQGMGAPPCSIVMTKWFSKKERGTKTGIWNI
SHNVGGMLVPPLVGIGVGIFGENHWQGGVFIFPAIIAMVIAVLVWINAKDTPESEGLPPIDEYRNDYENLEKADNANKMS
PKEILMKYVVKNKFVWFLCIANAFVYLIRFGVINWVPLYLTTVKGFSKNEAHAAYTIFEGMAIPSSLIVGLLSDKLFKGK
RMPLCIFSMVGVVIGTFVYWQATSILVISIAVSIIGCLIYVPQFLIGLSAMELVPKFAVGTTVGMCGLFGYVGGSLVANA
AIGVIVDRSGWDGCFILLLTGAILSTIFLFIVQRGHESKASKVA

Specific function: The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=441, Percent_Identity=25.3968253968254, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI4503847, Length=441, Percent_Identity=25.3968253968254, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI256219483, Length=441, Percent_Identity=25.3968253968254, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI256219543, Length=463, Percent_Identity=24.4060475161987, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI38093649, Length=398, Percent_Identity=24.6231155778894, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI223717983, Length=398, Percent_Identity=24.6231155778894, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI256219564, Length=366, Percent_Identity=24.5901639344262, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI46361976, Length=425, Percent_Identity=24.2352941176471, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788573, Length=449, Percent_Identity=43.8752783964365, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI87082310, Length=433, Percent_Identity=33.7182448036951, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI2367259, Length=422, Percent_Identity=31.2796208530806, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI2367379, Length=363, Percent_Identity=24.7933884297521, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789515, Length=446, Percent_Identity=22.1973094170404, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082320, Length=305, Percent_Identity=24.5901639344262, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789152, Length=415, Percent_Identity=21.4457831325301, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17564204, Length=375, Percent_Identity=25.6, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17564202, Length=370, Percent_Identity=25.6756756756757, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542316, Length=413, Percent_Identity=22.7602905569007, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI133930953, Length=301, Percent_Identity=23.5880398671096, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24656866, Length=492, Percent_Identity=21.1382113821138, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45550478, Length=492, Percent_Identity=21.1382113821138, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24656861, Length=492, Percent_Identity=21.1382113821138, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48511; Mature: 48511

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKWLKPAPAIERLPADMIDRVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLVQEYG
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHC
FSTAEIGLLGSVMAIVYGFSKFFMGNLSDKAFAQRFIAVGLFLSGLVNICFGFASSFGMI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTLLVVNGIVQGMGAPPCSIVMTKWFSKKERGTKTGIWNISHNVGGMLVPPLVGIGVGIF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEHHHHHHCCHHCC
GENHWQGGVFIFPAIIAMVIAVLVWINAKDTPESEGLPPIDEYRNDYENLEKADNANKMS
CCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
PKEILMKYVVKNKFVWFLCIANAFVYLIRFGVINWVPLYLTTVKGFSKNEAHAAYTIFEG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
MAIPSSLIVGLLSDKLFKGKRMPLCIFSMVGVVIGTFVYWQATSILVISIAVSIIGCLIY
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPQFLIGLSAMELVPKFAVGTTVGMCGLFGYVGGSLVANAAIGVIVDRSGWDGCFILLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHH
GAILSTIFLFIVQRGHESKASKVA
HHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFKWLKPAPAIERLPADMIDRVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLVQEYG
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHC
FSTAEIGLLGSVMAIVYGFSKFFMGNLSDKAFAQRFIAVGLFLSGLVNICFGFASSFGMI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTLLVVNGIVQGMGAPPCSIVMTKWFSKKERGTKTGIWNISHNVGGMLVPPLVGIGVGIF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEHHHHHHCCHHCC
GENHWQGGVFIFPAIIAMVIAVLVWINAKDTPESEGLPPIDEYRNDYENLEKADNANKMS
CCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
PKEILMKYVVKNKFVWFLCIANAFVYLIRFGVINWVPLYLTTVKGFSKNEAHAAYTIFEG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
MAIPSSLIVGLLSDKLFKGKRMPLCIFSMVGVVIGTFVYWQATSILVISIAVSIIGCLIY
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPQFLIGLSAMELVPKFAVGTTVGMCGLFGYVGGSLVANAAIGVIVDRSGWDGCFILLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHH
GAILSTIFLFIVQRGHESKASKVA
HHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 3042749 [H]