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The map label for this gene is murB

Identifier: 49481099

GI number: 49481099

Start: 4830407

End: 4831324

Strand: Reverse

Name: murB

Synonym: BT9727_4778

Alternate gene names: 49481099

Gene position: 4831324-4830407 (Counterclockwise)

Preceding gene: 49478874

Following gene: 49481095

Centisome position: 92.24

GC content: 36.17

Gene sequence:

>918_bases
ATGAATATGCAAGAGGTTTATGAATATTTAAGTACGGTATTGCCTGAAGGTCATGTGAAACAAGATGAAATGTTAAAGAA
TCATACGCATATTAAAGTTGGTGGAAAAGCAGATGTGTTCGTTGCGCCGACAAATTATGATGAAATTCAAGAAGTTATTA
AATATGCTAACAAATATAATATTCCAGTTACGTTTTTAGGAAACGGATCGAATGTCATTATTAAAGACGGTGGAATTCGC
GGGATTACAGTAAGTTTAATTCATATTACAGGTGTTACTGTAACAGGAACGACAATTGTAGCACAGTGCGGTGCAGCAAT
TATTGACGTATCACGTATTGCGTTAGACCATAACTTAACGGGTCTTGAGTTCGCTTGTGGTATTCCAGGTTCAGTTGGCG
GAGCATTATATATGAATGCAGGTGCATACGGCGGTGAAATTTCGTTTGTATTAACAGAAGCTGTCGTAATGACAGGTGAT
GGAGAGCTACGTACTTTGACGAAAGAAGCATTTGAATTTGGATATCGTAAGAGTGTATTTGCGAACAATCATTACATTAT
TCTTGAAGCGAGATTTGAACTTGAAGAAGGTTTATATGAAGAAATTAAAGCAAAAATGGATGATTTAACGTTTAAACGTG
AGTCAAAACAACCTCTAGAATATCCTTCATGTGGTAGCGTATTTAAACGCCCACCAAATAACTTTGCTGGTAAATTGATT
CAAGAATCAGGGCTACAAGGTAAGCGAATTGGTGGAGTGGAAGTTTCTTTAAAACACGCTGGATTTATGGTAAATGTTGA
TAACGGAACAGCACAAGATTACATCGATTTAATTCACTTCGTACAAAAAACAGTTGAAGAGAAATTTGGCGTGAAGTTAG
AGCGTGAAGTAAGGATTATTGGAGAAGATAAAGAATAA

Upstream 100 bases:

>100_bases
GGTACACTGTATCCACCACTTTAGGTTCGTTCATGTATGTGGGGATATTATGGGCCCGTATAACGGGATAAAAAGAATAT
AGAAATAGAGGAATCGTAAA

Downstream 100 bases:

>100_bases
CATATACGTATGAAGTTGCGAATTATTTTAAAATAATATTTGGGTATTGTTGACAATTTGTTTTCAATTCAATATAATGG
CTAATAATTTAACAAATAAC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase 2 [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYNIPVTFLGNGSNVIIKDGGIR
GITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLTGLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGD
GELRTLTKEAFEFGYRKSVFANNHYIILEARFELEEGLYEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI
QESGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRIIGEDKE

Sequences:

>Translated_305_residues
MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYNIPVTFLGNGSNVIIKDGGIR
GITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLTGLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGD
GELRTLTKEAFEFGYRKSVFANNHYIILEARFELEEGLYEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI
QESGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRIIGEDKE
>Mature_305_residues
MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYNIPVTFLGNGSNVIIKDGGIR
GITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLTGLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGD
GELRTLTKEAFEFGYRKSVFANNHYIILEARFELEEGLYEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI
QESGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRIIGEDKE

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33561; Mature: 33561

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYN
CCHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEECCCEEEEEECCCHHHHHHHHHHHHCCC
IPVTFLGNGSNVIIKDGGIRGITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLT
CEEEEEECCCEEEEECCCCCEEEEEEEEEEEEEEECHHHHHHCCHHHHHHHHHHCCCCCC
GLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGDGELRTLTKEAFEFGYRKSVF
CEEEECCCCCCCCCEEEEECCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHCCCCCEEE
ANNHYIILEARFELEEGLYEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI
ECCCEEEEEEEECHHCCHHHHHHHHHHHCEECCCCCCCCCCCCCCHHHCCCCCHHHHHHH
QESGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRII
HHCCCCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEE
GEDKE
ECCCC
>Mature Secondary Structure
MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYN
CCHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEECCCEEEEEECCCHHHHHHHHHHHHCCC
IPVTFLGNGSNVIIKDGGIRGITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLT
CEEEEEECCCEEEEECCCCCEEEEEEEEEEEEEEECHHHHHHCCHHHHHHHHHHCCCCCC
GLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGDGELRTLTKEAFEFGYRKSVF
CEEEECCCCCCCCCEEEEECCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHCCCCCEEE
ANNHYIILEARFELEEGLYEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI
ECCCEEEEEEEECHHCCHHHHHHHHHHHCEECCCCCCCCCCCCCCHHHCCCCCHHHHHHH
QESGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRII
HHCCCCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEE
GEDKE
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]