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The map label for this gene is mcpA

Identifier: 49481071

GI number: 49481071

Start: 4771707

End: 4773707

Strand: Reverse

Name: mcpA

Synonym: BT9727_4724

Alternate gene names: 49481071

Gene position: 4773707-4771707 (Counterclockwise)

Preceding gene: 49478852

Following gene: 49480361

Centisome position: 91.14

GC content: 36.63

Gene sequence:

>2001_bases
ATGTTAAGAAGTTTACGTTTAAAAATTGCGGTAGTATTTTCGGTACTTATTTCTATGATGTTCGTAATATTAGGTACAGC
TATGTATCAATTACAGAAAGAGAAGGAAGTGCGCTCCTTAGACCAGTATTCTCAAAATACGATGGATCTTGTGACAGAGC
AGTTAACTGCATTTATGCAGCGAATTGAAGAAGATATGGGGCATTATGGAAGTCATGATGATATTCAAAACATGTTACAA
GATGGAGTTACTCCAGAGGAAGAGAGCTTTATTTTAAAAGAGTTTTCAAGATTTAAAAAGAACCATCCTGATATTTTAGA
TGTATACATTGGGACAAAAGATAAAAAAACGTTGAGCGCAAATCTCGCTGACGGAGGAAAAGTACCAGAAGGGTATGATC
CAACGAGTCGTCAGTGGTATAAAGCATCAGAATCTGATACGAAATCGATTATTTGGGGACAACCACAATATGAAATCGCG
ACAGGTAAGTTAAGCATTGGAGTGTCAAAAGCAATTGTCGGACAAGATGGATCTGTATTAGGGGTAGTAGCAATGGATGT
ATCATTAGGAACAATTCAAAAGCTACTCCACAATATTCAATATAATAACGGCGGAGAAATGTTTATCGTAAATGATAAAA
ATATTGCCATTGTATATCCAGAGAAAGTAGGAAAAGATGTTTCAAAGGAACCACTTTTAAAAAGTTTGAATAAAGATGAA
ACAAAATTTGCGGTGACAACATTAGGCGGAAAAGATGTAGTAGCCTATAGTCAACTGTTTGATAAGATGAAATGGAAAAT
TGGGATTGTTTATCCGAAAGAAACGATTGATGGGCTATTAAATAGTACGAGAAATACAGTCATTATAATGGCATGTATTA
GCTTATTCGTTGGAATTGTAGCTTCATACTTGTTCTCAAGAAGATTAGCAAGACCACTGCAACTATTAACGAATCACGTT
CAAAAAGTAGCAGAAGGTGATTTAACGTTGCAAATGAAAGTGACAAGTAAGGATGAAGTTGGAGAACTGACGAACCATTT
TAATCATATGGTTGAGCAAATGAATGAAATGGTAAGTAAAATTAAAAATAGTGTATCAACCGTGCAACAATCAACGAATA
ATCTACATTATTTAACGAATGAGACTGTAGCAGCTAGTAAAGAAGTGTCAGGTGCAATGGATGATGTAAGCGGAGGAGCA
TCCACTCTTGCAAATAGTGTAGATGAAGTTTCAGAGCAGCTTGAAAATATGATACAGTCAGTGGAACAAATGAATAGCTC
CGTTGGTGAAATAAAAGGAGTAGCTGGCAAAGCAGAAGAGGCATCTAAGCAAGGATTGAATACGATGCGAAATTTAGTTC
GTACAAGAGAACAATCCTCTTCAATTGTTGTTCATACAGAGGAAGCATCTGGAAAGTTGGAGCAAAGGGTTGGATCGATT
CAAAATGTTGTAGAGCTTATAAAAGGTATTTCGGATCAAACGAATTTACTTGCTTTAAATGCTTCAATTGAGGCGGCACG
TGCGGGTGAACAAGGTAAAGGCTTTGCTGTTGTTGCTGAAGAGGTTCGAAAATTAGCGGAACAATCAAAAGAAGCAACAG
TAGAAATTGCGACGATGATTGGTGATGTACAAGTAGAGGTAAGACGAGTTGTAGAAGTTGTAAGTAAATTAAAAGATATT
GCGGATATACAAAATAATGTTACGACAGAAGCAGAGGCGGAGTTCCGTACAATTATGTCAGTTGTTAATATCATTAGTAC
TTCAGTGGAACAAATTGTAGAAGAGGTACATAACATCGGTCACGAGCAAGGAGAAATTACAGCGGTAATGCATACAATTG
CTGGTACGAGTCAAGAAAGTGCAGCTGTTTCGGAAGAAGTAAATGCTGCAACTGAATCACAAGTGAATCATTTAGAAAAG
GTAGCTCATACGATGGAAAGTTTGACGGAGCATATGAGAGACTTGGAAAGATTGGTTGAGCAATTTAAAATAGAGGAATA
A

Upstream 100 bases:

>100_bases
TGAAGTGAGAATTAGTTTCAATTTTTTAATTTTATCTATTATACTTAATATAGTGATTAATAATATTTGAATTCAATGCG
AAGGGGATGCTTTGGGGGAT

Downstream 100 bases:

>100_bases
CAAATTAGTAAAATGATGCGTATTTCGGTAAAATAGATAATGGATATATAAGAAGCAATTATAGGAGGAAGACTACTATG
GCAATTGTTGACGTATCGAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MLRSLRLKIAVVFSVLISMMFVILGTAMYQLQKEKEVRSLDQYSQNTMDLVTEQLTAFMQRIEEDMGHYGSHDDIQNMLQ
DGVTPEEESFILKEFSRFKKNHPDILDVYIGTKDKKTLSANLADGGKVPEGYDPTSRQWYKASESDTKSIIWGQPQYEIA
TGKLSIGVSKAIVGQDGSVLGVVAMDVSLGTIQKLLHNIQYNNGGEMFIVNDKNIAIVYPEKVGKDVSKEPLLKSLNKDE
TKFAVTTLGGKDVVAYSQLFDKMKWKIGIVYPKETIDGLLNSTRNTVIIMACISLFVGIVASYLFSRRLARPLQLLTNHV
QKVAEGDLTLQMKVTSKDEVGELTNHFNHMVEQMNEMVSKIKNSVSTVQQSTNNLHYLTNETVAASKEVSGAMDDVSGGA
STLANSVDEVSEQLENMIQSVEQMNSSVGEIKGVAGKAEEASKQGLNTMRNLVRTREQSSSIVVHTEEASGKLEQRVGSI
QNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATVEIATMIGDVQVEVRRVVEVVSKLKDI
ADIQNNVTTEAEAEFRTIMSVVNIISTSVEQIVEEVHNIGHEQGEITAVMHTIAGTSQESAAVSEEVNAATESQVNHLEK
VAHTMESLTEHMRDLERLVEQFKIEE

Sequences:

>Translated_666_residues
MLRSLRLKIAVVFSVLISMMFVILGTAMYQLQKEKEVRSLDQYSQNTMDLVTEQLTAFMQRIEEDMGHYGSHDDIQNMLQ
DGVTPEEESFILKEFSRFKKNHPDILDVYIGTKDKKTLSANLADGGKVPEGYDPTSRQWYKASESDTKSIIWGQPQYEIA
TGKLSIGVSKAIVGQDGSVLGVVAMDVSLGTIQKLLHNIQYNNGGEMFIVNDKNIAIVYPEKVGKDVSKEPLLKSLNKDE
TKFAVTTLGGKDVVAYSQLFDKMKWKIGIVYPKETIDGLLNSTRNTVIIMACISLFVGIVASYLFSRRLARPLQLLTNHV
QKVAEGDLTLQMKVTSKDEVGELTNHFNHMVEQMNEMVSKIKNSVSTVQQSTNNLHYLTNETVAASKEVSGAMDDVSGGA
STLANSVDEVSEQLENMIQSVEQMNSSVGEIKGVAGKAEEASKQGLNTMRNLVRTREQSSSIVVHTEEASGKLEQRVGSI
QNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATVEIATMIGDVQVEVRRVVEVVSKLKDI
ADIQNNVTTEAEAEFRTIMSVVNIISTSVEQIVEEVHNIGHEQGEITAVMHTIAGTSQESAAVSEEVNAATESQVNHLEK
VAHTMESLTEHMRDLERLVEQFKIEE
>Mature_666_residues
MLRSLRLKIAVVFSVLISMMFVILGTAMYQLQKEKEVRSLDQYSQNTMDLVTEQLTAFMQRIEEDMGHYGSHDDIQNMLQ
DGVTPEEESFILKEFSRFKKNHPDILDVYIGTKDKKTLSANLADGGKVPEGYDPTSRQWYKASESDTKSIIWGQPQYEIA
TGKLSIGVSKAIVGQDGSVLGVVAMDVSLGTIQKLLHNIQYNNGGEMFIVNDKNIAIVYPEKVGKDVSKEPLLKSLNKDE
TKFAVTTLGGKDVVAYSQLFDKMKWKIGIVYPKETIDGLLNSTRNTVIIMACISLFVGIVASYLFSRRLARPLQLLTNHV
QKVAEGDLTLQMKVTSKDEVGELTNHFNHMVEQMNEMVSKIKNSVSTVQQSTNNLHYLTNETVAASKEVSGAMDDVSGGA
STLANSVDEVSEQLENMIQSVEQMNSSVGEIKGVAGKAEEASKQGLNTMRNLVRTREQSSSIVVHTEEASGKLEQRVGSI
QNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATVEIATMIGDVQVEVRRVVEVVSKLKDI
ADIQNNVTTEAEAEFRTIMSVVNIISTSVEQIVEEVHNIGHEQGEITAVMHTIAGTSQESAAVSEEVNAATESQVNHLEK
VAHTMESLTEHMRDLERLVEQFKIEE

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=305, Percent_Identity=28.8524590163934, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1787690, Length=378, Percent_Identity=27.2486772486773, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1788195, Length=240, Percent_Identity=29.1666666666667, Blast_Score=109, Evalue=7e-25,
Organism=Escherichia coli, GI1788194, Length=316, Percent_Identity=27.8481012658228, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789453, Length=329, Percent_Identity=30.0911854103343, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73465; Mature: 73465

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSLRLKIAVVFSVLISMMFVILGTAMYQLQKEKEVRSLDQYSQNTMDLVTEQLTAFMQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIEEDMGHYGSHDDIQNMLQDGVTPEEESFILKEFSRFKKNHPDILDVYIGTKDKKTLSA
HHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHCC
NLADGGKVPEGYDPTSRQWYKASESDTKSIIWGQPQYEIATGKLSIGVSKAIVGQDGSVL
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEECCCCEEEECCEEECCHHHHHCCCCCCEE
GVVAMDVSLGTIQKLLHNIQYNNGGEMFIVNDKNIAIVYPEKVGKDVSKEPLLKSLNKDE
EEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEECCHHHCCCCCHHHHHHHCCCCC
TKFAVTTLGGKDVVAYSQLFDKMKWKIGIVYPKETIDGLLNSTRNTVIIMACISLFVGIV
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ASYLFSRRLARPLQLLTNHVQKVAEGDLTLQMKVTSKDEVGELTNHFNHMVEQMNEMVSK
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IKNSVSTVQQSTNNLHYLTNETVAASKEVSGAMDDVSGGASTLANSVDEVSEQLENMIQS
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VEQMNSSVGEIKGVAGKAEEASKQGLNTMRNLVRTREQSSSIVVHTEEASGKLEQRVGSI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHCCHHHHHHHHH
QNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATVEIATMI
HHHHHHHHCCCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GDVQVEVRRVVEVVSKLKDIADIQNNVTTEAEAEFRTIMSVVNIISTSVEQIVEEVHNIG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HEQGEITAVMHTIAGTSQESAAVSEEVNAATESQVNHLEKVAHTMESLTEHMRDLERLVE
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFKIEE
HHCCCC
>Mature Secondary Structure
MLRSLRLKIAVVFSVLISMMFVILGTAMYQLQKEKEVRSLDQYSQNTMDLVTEQLTAFMQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIEEDMGHYGSHDDIQNMLQDGVTPEEESFILKEFSRFKKNHPDILDVYIGTKDKKTLSA
HHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHCC
NLADGGKVPEGYDPTSRQWYKASESDTKSIIWGQPQYEIATGKLSIGVSKAIVGQDGSVL
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEECCCCEEEECCEEECCHHHHHCCCCCCEE
GVVAMDVSLGTIQKLLHNIQYNNGGEMFIVNDKNIAIVYPEKVGKDVSKEPLLKSLNKDE
EEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEECCHHHCCCCCHHHHHHHCCCCC
TKFAVTTLGGKDVVAYSQLFDKMKWKIGIVYPKETIDGLLNSTRNTVIIMACISLFVGIV
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ASYLFSRRLARPLQLLTNHVQKVAEGDLTLQMKVTSKDEVGELTNHFNHMVEQMNEMVSK
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IKNSVSTVQQSTNNLHYLTNETVAASKEVSGAMDDVSGGASTLANSVDEVSEQLENMIQS
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VEQMNSSVGEIKGVAGKAEEASKQGLNTMRNLVRTREQSSSIVVHTEEASGKLEQRVGSI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHCCHHHHHHHHH
QNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATVEIATMI
HHHHHHHHCCCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GDVQVEVRRVVEVVSKLKDIADIQNNVTTEAEAEFRTIMSVVNIISTSVEQIVEEVHNIG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HEQGEITAVMHTIAGTSQESAAVSEEVNAATESQVNHLEKVAHTMESLTEHMRDLERLVE
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFKIEE
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353924; 9384377 [H]