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The map label for this gene is comGA

Identifier: 49480954

GI number: 49480954

Start: 4049309

End: 4050352

Strand: Reverse

Name: comGA

Synonym: BT9727_3985

Alternate gene names: 49480954

Gene position: 4050352-4049309 (Counterclockwise)

Preceding gene: 49480645

Following gene: 49480953

Centisome position: 77.33

GC content: 38.31

Gene sequence:

>1044_bases
ATGAATGGAATTGAAAGCTTTGCGAATATGATTTTGAAAGAAGCGTGCAGGGTACAAGCGTCGGACTTACATATTGTGCC
CCGGCAGAAGGATGTAGTGGTTCAGCTGCGTATAGGAAAAGATTTAATGACGAAACAATGCATTGAAAAGGAGTTTGGAG
AAAAACTTGTTTCACACTTTAAATTTTTAGCATCCATGGATATAGGGGAGAGGCGGAAGCCACAAAATGGTTCACTGTAT
TTACAAATGGATGGACAGGAGGTGTATTTGCGCCTTTCCACGCTTCCAACCGTATACCAAGAAAGTCTCGTTATTCGTCT
TCATTTACAAGCATCTATTCAGCCGTTATCTCATCTTTCGTTATTTCCAAGTACAGCGAAGAAACTACTTTCTTTTTTAC
GTTATTCTCATGGGTTACTCGTATTTACTGGACCGACTGGTTCAGGGAAGACAACAACAATGTATGCATTATTAGAGGTA
ATTAGAAAAAAGAAAACACGTCGCATCGTTACACTGGAAGATCCAGTTGAAAAAAGAAATGACGATGTATTACAAATTCA
AATAAATGAAAAAGCAGGTATCACATATGAGGCTGGACTAAAGGCTATTTTGCGTCATGATCCAGATGTTATTTTAGTCG
GTGAAATTCGTGATGAAGAAACAGCGAAAATTGCTATAAGAGCAAGTTTGACTGGCCATTTAGTAATGACGACATTGCAT
ACGAATGATGCGAGAGGGGCGATACTTCGGTTCATGGATTTTGGCATAACGAGGCAAGAAATCGAACAATCTTTATTAGC
TATAGCTGCACAGCGACTTGTCGAATTAAAGTGTCCGTTTTGCAAAAGAAAGTGCTCAACTTTATGCAAATCAATGAGGC
AAGTAAGGCAAGCGAGTATTTATGAGTTGTTATATGGATATGAGTTAAAACAAGCGATTAAAGAAGCAAACGGGGAATGT
GTCACATACAAGCACGAAACATTACAATCTTCGATACGAAAAGGATACGCTTTAGGGTTTTTAGAAGAAGATGTTTATGT
TTAA

Upstream 100 bases:

>100_bases
CACAAACATATTTTTCCTTTTCTCTCTAGTGAAAATACAAAAATGCCGATTTTTCTTATGAATTTTTTCATGCTATATAC
ATAGTGGGGAGGGAAAAATG

Downstream 100 bases:

>100_bases
GGAAGTATGGAGTTTAAGTGATCAAGTCATATTACTGAAACGATTAGGAGAACTATTAGAAAAAGGATACTCCCTTTTGC
AGGCATTAGAATTTTTACGA

Product: comG operon protein 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKQCIEKEFGEKLVSHFKFLASMDIGERRKPQNGSLY
LQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHLSLFPSTAKKLLSFLRYSHGLLVFTGPTGSGKTTTMYALLEV
IRKKKTRRIVTLEDPVEKRNDDVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTLH
TNDARGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQASIYELLYGYELKQAIKEANGEC
VTYKHETLQSSIRKGYALGFLEEDVYV

Sequences:

>Translated_347_residues
MNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKQCIEKEFGEKLVSHFKFLASMDIGERRKPQNGSLY
LQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHLSLFPSTAKKLLSFLRYSHGLLVFTGPTGSGKTTTMYALLEV
IRKKKTRRIVTLEDPVEKRNDDVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTLH
TNDARGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQASIYELLYGYELKQAIKEANGEC
VTYKHETLQSSIRKGYALGFLEEDVYV
>Mature_347_residues
MNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKQCIEKEFGEKLVSHFKFLASMDIGERRKPQNGSLY
LQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHLSLFPSTAKKLLSFLRYSHGLLVFTGPTGSGKTTTMYALLEV
IRKKKTRRIVTLEDPVEKRNDDVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTLH
TNDARGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQASIYELLYGYELKQAIKEANGEC
VTYKHETLQSSIRKGYALGFLEEDVYV

Specific function: Required for uptake of DNA by competent cells [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=276, Percent_Identity=43.4782608695652, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1786296, Length=275, Percent_Identity=40, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87082188, Length=155, Percent_Identity=40.6451612903226, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 39379; Mature: 39379

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKQCIEKEFGEKLVSHF
CCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
KFLASMDIGERRKPQNGSLYLQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHLS
HHHHHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCHHHHCCEEEEEEECCCCCHHHHHH
LFPSTAKKLLSFLRYSHGLLVFTGPTGSGKTTTMYALLEVIRKKKTRRIVTLEDPVEKRN
CCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCHHCCC
DDVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTLH
CCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCCEEEEEEEE
TNDARGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQASI
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YELLYGYELKQAIKEANGECVTYKHETLQSSIRKGYALGFLEEDVYV
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKQCIEKEFGEKLVSHF
CCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
KFLASMDIGERRKPQNGSLYLQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHLS
HHHHHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCHHHHCCEEEEEEECCCCCHHHHHH
LFPSTAKKLLSFLRYSHGLLVFTGPTGSGKTTTMYALLEVIRKKKTRRIVTLEDPVEKRN
CCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCHHCCC
DDVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTLH
CCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCCEEEEEEEE
TNDARGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQASI
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YELLYGYELKQAIKEANGECVTYKHETLQSSIRKGYALGFLEEDVYV
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590; 9723928 [H]