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The map label for this gene is lcoR

Identifier: 49480400

GI number: 49480400

Start: 4997898

End: 4998569

Strand: Reverse

Name: lcoR

Synonym: BT9727_4944

Alternate gene names: 49480400

Gene position: 4998569-4997898 (Counterclockwise)

Preceding gene: 49481245

Following gene: 49480399

Centisome position: 95.43

GC content: 41.22

Gene sequence:

>672_bases
ATGAAGATACTTGTAGTGGATGATGAGTCGAGTATTCGTAATTTGATTCGGATGCAGCTTGAGATGGAAGGATATGAAGT
GCTCACGGCGGCTGATGGGAGAGAAGCTTTAGAGAGATGGAATGAAGGGCCGGATGTTTTGATTTTGGATGTTATGCTTC
CAGATACAGATGGGTATGAATTACTTCGTTTGTTCCGTGAGAAGGATAGGGATATTCCAGTACTCATGTTAACTGCGAAG
AGTCAAATGAATGATAAATTGCTTGGTTTGCAGCTGGGCGCTGATGATTACGTGACGAAGCCATTTAATTATGCGGAGCT
TATTCTTCGGGTCAAGAATATGACGCGGCGTGTGAAGAAGAAAGAGGTAACGGTAAGTCATGAAGTAATCGAGGCAGGAG
AGATAACGATCTGTCCTAAGGAAAGAAAAGTGCATGTGAGTGGACAAGAAATTCAGTTAACGTACAGAGAGTTTAATTTA
TGTCAGTTGTTTGTTTCTAATCCGCAGCGTGTATTTATGAGAGATGAGTTACTTGAGAAAGTATGGGGATTTGAGTATAT
CGGAAATACGAGAGCGGTTGATATTATGGTGCAAAGATTGCGGAAGAAGTTAGGGGATAGCGGGGAATATATTAAGACCA
TTTATGGCGTTGGCTATAAACTGGATTGTTAA

Upstream 100 bases:

>100_bases
GTATTGTCGTTCAATATATGTTCGACAATACCCTCTCTTTTTTTATAAGATTTTTGCTATACTAAACTGTACTATAATAC
GGGATGGAAGGAGGAGAATA

Downstream 100 bases:

>100_bases
GTGGTGATGGTATGTCTTTAAAAAGAAATATGGTGTTTGGAATTGTTGGACTGTTAATCCCGATATTCGTTCTTTTGTAC
GCAGTTGTTTATATTACGTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKILVVDDESSIRNLIRMQLEMEGYEVLTAADGREALERWNEGPDVLILDVMLPDTDGYELLRLFREKDRDIPVLMLTAK
SQMNDKLLGLQLGADDYVTKPFNYAELILRVKNMTRRVKKKEVTVSHEVIEAGEITICPKERKVHVSGQEIQLTYREFNL
CQLFVSNPQRVFMRDELLEKVWGFEYIGNTRAVDIMVQRLRKKLGDSGEYIKTIYGVGYKLDC

Sequences:

>Translated_223_residues
MKILVVDDESSIRNLIRMQLEMEGYEVLTAADGREALERWNEGPDVLILDVMLPDTDGYELLRLFREKDRDIPVLMLTAK
SQMNDKLLGLQLGADDYVTKPFNYAELILRVKNMTRRVKKKEVTVSHEVIEAGEITICPKERKVHVSGQEIQLTYREFNL
CQLFVSNPQRVFMRDELLEKVWGFEYIGNTRAVDIMVQRLRKKLGDSGEYIKTIYGVGYKLDC
>Mature_223_residues
MKILVVDDESSIRNLIRMQLEMEGYEVLTAADGREALERWNEGPDVLILDVMLPDTDGYELLRLFREKDRDIPVLMLTAK
SQMNDKLLGLQLGADDYVTKPFNYAELILRVKNMTRRVKKKEVTVSHEVIEAGEITICPKERKVHVSGQEIQLTYREFNL
CQLFVSNPQRVFMRDELLEKVWGFEYIGNTRAVDIMVQRLRKKLGDSGEYIKTIYGVGYKLDC

Specific function: This Protein Is A Positive Regulator For The Phosphate Regulon. Transcription Of This Operon Is Positively Regulated By Phob And Phor When Phosphate Is Limited. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=37.0044052863436, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.5132743362832, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.1351351351351, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=33.1858407079646, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=36.4444444444444, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=32.8828828828829, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=36.322869955157, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=33.4821428571429, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=34.9344978165939, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=33.7777777777778, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=30.8035714285714, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=31.5315315315315, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=31.5789473684211, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=31.7391304347826, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788550, Length=134, Percent_Identity=32.8358208955224, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790299, Length=121, Percent_Identity=33.0578512396694, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788713, Length=103, Percent_Identity=38.8349514563107, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=111, Percent_Identity=38.7387387387387, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=35.6435643564356, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=36.1111111111111, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=37.2549019607843, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25896; Mature: 25896

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVVDDESSIRNLIRMQLEMEGYEVLTAADGREALERWNEGPDVLILDVMLPDTDGYE
CEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCEEEEEEEECCCCCHH
LLRLFREKDRDIPVLMLTAKSQMNDKLLGLQLGADDYVTKPFNYAELILRVKNMTRRVKK
HHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
KEVTVSHEVIEAGEITICPKERKVHVSGQEIQLTYREFNLCQLFVSNPQRVFMRDELLEK
HHHHHHHHHHCCCCEEECCCCCEEEECCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHH
VWGFEYIGNTRAVDIMVQRLRKKLGDSGEYIKTIYGVGYKLDC
HCCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEECC
>Mature Secondary Structure
MKILVVDDESSIRNLIRMQLEMEGYEVLTAADGREALERWNEGPDVLILDVMLPDTDGYE
CEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCEEEEEEEECCCCCHH
LLRLFREKDRDIPVLMLTAKSQMNDKLLGLQLGADDYVTKPFNYAELILRVKNMTRRVKK
HHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
KEVTVSHEVIEAGEITICPKERKVHVSGQEIQLTYREFNLCQLFVSNPQRVFMRDELLEK
HHHHHHHHHHCCCCEEECCCCCEEEECCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHH
VWGFEYIGNTRAVDIMVQRLRKKLGDSGEYIKTIYGVGYKLDC
HCCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1554697 [H]