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The map label for this gene is fadB

Identifier: 49479427

GI number: 49479427

Start: 4766093

End: 4768474

Strand: Reverse

Name: fadB

Synonym: BT9727_4719

Alternate gene names: 49479427

Gene position: 4768474-4766093 (Counterclockwise)

Preceding gene: 49481070

Following gene: 49481066

Centisome position: 91.04

GC content: 38.96

Gene sequence:

>2382_bases
ATGTTCCAAATTAAAAAGGCTGCTGTTCTAGGGTCAGGCGTAATGGGTTCAGGAATTGCGGCACACTTAGCTAATATTGG
TATTCCGACATTATTGCTTGATATTGTACCACCTGCGCTTACGAAAGAAGAAGAAGCGAAGGGACTTACATTAGAACATA
AAAGTGTGAGAAATCGTTTTAGTAATACGGCTGTGCAAAAACTATTAAAGCAAAAACCAGCTCCTCTGACAGTGAAAGGA
AATTTAGCACTGATTGAAGCAGGTAACTTAGAAGATGATCTTGAGCGTCTAGCTGATGTAGATTGGATTATTGAAGTAGT
AGTTGAAAACTTAGACATTAAAAAGAAACTATTTGAAAAAGTAGATGCTGTTCGTAAACCGGGTTCTATCGTAAGCTCGA
ATACGTCAGGCATTTCAGTTGAAAAAATGGCAGAAGGTCGTTCAGACGACTTCCAGAAACACTTCTTAGGCACACACTTT
TTTAACCCACCACGATATTTAAAACTTCTAGAGGTAATACCGACGAAAAAAACTGATCCACAAGTATTAAGCTTCATGAA
ACTATTTGGCGAAGACGTTCTTGGAAAAGGCGTTGTTATCGCAAAAGACACACCAAACTTTATTGGAAACCGCATCGGTA
CGTACGGTTTATTAGTAACTCTTCAAGAGATGGTAAAACGCGGCTATAGCATTGGAGAAGTTGATTCAGTAACAGGCCCA
CTTATTGGTCGTCCGAAGAGCGCAACGTTCCGTACTTTAGATGTTGTCGGTTTAGATACATTCGTACACGTTGCAAATAA
CGTATATGAAAACGTACAAGAAAAAGAGCGCGATGTATTTAAAGTACCAGCTTTCATGCATGACATGCTTGATAAAAAAT
GGCTTGGAAGCAAAACAGGTCAAGGCTTCTTCTTAAAACAAGGAAAAGAAATTTTAGAATTAAATCCAGAAACGATGGAG
TACGAAGCTCGTAAAAAATTAAAAGCTGCATCGATTGAGTTAAGTAAACAAGAAAAAGGTTTATCGAATAAATTGAAAGC
GCTTGTATATGCGAAAGACCGCGCAGGAGAGTTGTTATGGAATATCATCACACCGACTCTTTTATATTCTGCAAAACTTC
ATAAAGAGATTGCTGACGATATCGTTGCAATTGACCAAGCGATGAAGTGGGGCTTCGGCTGGGAGCAAGGCCCATTTGAA
GTTTGGGATGCAATTGGCGTTGAAAAGTCCGTTCAAAAGATGGAAGAAAGCGGCGCAGTTATTCCGGCTTGGGTGAAAGA
AATGTTAGAGAAAGGTTTCACTACTTTCTACAAACATGATAACGGAGATAGCTATTATTACGATAATGGCGAATATAAGC
TAATTGAGCGTAATAAAAAGGCAATTTCTCTTAAACAATTAAAAGCGAAAAATGGTGTATTAAAGAAAAATAGCGGAGCG
AGCTTAATCGATTTAGGCGACGGTATCCTTTGCTTAGAATTCCATTCGAAGAGCAATGCAATCGGTATGGATATTACGCA
AATGATTAACTACGCTGTTGATGAAGTAGAAAAGAATTATAAAGGTCTTGTTATCGGTAACCAATCGAAGAACTTCTGCG
TTGGTGCGAACTTAGCAATGATCTTAATGGAAGCACAAGACGACAACTACTTTGAAATTGAGTGGGTTGTGAAAAACTTC
CAAGATGCAATGACGAAAATTAAATACTCTTCTAAGCCAGTTGTAGCAGCACCATACGGTATGACGCTTGGTGGAGGTAC
AGAAGTTTGCTTACCAGCAGCGAGCATTCAAGCTTCTAGTGAAACGTATATGGGCTTAGTAGAAGTTGGTGTTGGCTTAA
TCCCTGGCGGAGGCGGTAATAAAGAGCTATACATTAAACACTTAAATAAAATGGCAAACGGCGTAGAATTTGATCTACAA
AAAGTTGCAAATAAAGTGTTCGAAACAGTCGCAATGGCGAAAGTTTCAACTTCAGGACAAGAAGCGGTTTCTCATAACTT
CTTAGGTGATAAAGACGGTATTAGTGTGAATGGTGATCACTTACTATACGATGCAAAACAGAAAGCACTTGCTTTATATG
AAGCTGGTTACAAAGCACCGATTCGTAAAAAGATACCGGTTGTTGGTGAAACAGGATATGCAACTCTTGCACTTGGTGCA
GAAGCAATGCATTTATCTGGTTACATTTCAGAGTACGACCTTCATATTGCGAAGAAACTTGCATATGTCATCGCAGGCGG
AAAAGTGCCGTACGGAACAGAAGTTGATGAGCAGTATTTATTAGATGTAGAACGTGAAGCATTTATTAGCTTAGTAAGTG
AGATGAAATCACAAGCAAGAATGCAGCACATGCTTGTAAAAGGAAAGCCATTACGTAACTAA

Upstream 100 bases:

>100_bases
TAAACAGTATCATATATTTATTAGTAGAGGCTCACTCATTGATTGCGACTTATGTCGAAAAATTGAATGAGCATTCATTC
AAGAATAGGGGGAGAATTGG

Downstream 100 bases:

>100_bases
TAACGAGGGGAGATATCGTTCATGAGAGAAGCTGTCATTGTTGCGGGAGCAAGAACACCAATTGGAAAAGCAAAGAGGGG
TTCATTAAAAACAGTTCGTC

Product: 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase/carnithine racemase fusion

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 793; Mature: 793

Protein sequence:

>793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKG
NLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHF
FNPPRYLKLLEVIPTKKTDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETME
YEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFE
VWDAIGVEKSVQKMEESGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNF
QDAMTKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQ
KVANKVFETVAMAKVSTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN

Sequences:

>Translated_793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKG
NLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHF
FNPPRYLKLLEVIPTKKTDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETME
YEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFE
VWDAIGVEKSVQKMEESGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNF
QDAMTKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQ
KVANKVFETVAMAKVSTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN
>Mature_793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKG
NLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHF
FNPPRYLKLLEVIPTKKTDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETME
YEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFE
VWDAIGVEKSVQKMEESGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNF
QDAMTKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQ
KVANKVFETVAMAKVSTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=301, Percent_Identity=29.2358803986711, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI296179427, Length=322, Percent_Identity=28.2608695652174, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI20127408, Length=417, Percent_Identity=25.8992805755396, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI261878539, Length=264, Percent_Identity=28.030303030303, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI68989263, Length=264, Percent_Identity=28.030303030303, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI115430219, Length=229, Percent_Identity=27.5109170305677, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1787661, Length=306, Percent_Identity=27.4509803921569, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790281, Length=318, Percent_Identity=24.8427672955975, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1788682, Length=283, Percent_Identity=27.208480565371, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17553560, Length=308, Percent_Identity=32.1428571428571, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17549919, Length=303, Percent_Identity=30.03300330033, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71985923, Length=416, Percent_Identity=26.9230769230769, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508951, Length=418, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17508953, Length=418, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17563036, Length=301, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17558304, Length=425, Percent_Identity=25.4117647058824, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25144276, Length=303, Percent_Identity=27.7227722772277, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71985930, Length=327, Percent_Identity=24.1590214067278, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=144, Percent_Identity=34.0277777777778, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45549573, Length=275, Percent_Identity=28, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19921000, Length=417, Percent_Identity=25.6594724220624, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24583077, Length=417, Percent_Identity=25.6594724220624, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24583079, Length=417, Percent_Identity=25.6594724220624, Blast_Score=87, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 87429; Mature: 87429

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRF
CCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCHHCCCCEEEHHHHHHHH
SNTAVQKLLKQKPAPLTVKGNLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEK
HHHHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHFFNPPRYLKLLEVIPTKKTDP
HHHHCCCCCEEECCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCH
QVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTG
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QGFFLKQGKEILELNPETMEYEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLW
CCEEHHCCCHHHHCCCHHHHHHHHHHHHHHHEEHHHHHCCHHHHHHEEEEECCCHHHHHH
NIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFEVWDAIGVEKSVQKMEESGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCC
IPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
CHHHHHHHHHCCCCEEEEECCCCCEEEECCCEEEEECCCHHHHHHHHHHHCCCEECCCCC
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAM
CEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCEEE
ILMEAQDDNYFEIEWVVKNFQDAMTKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASS
EEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEECCCCEEECCCCCEEEECHHCCCCC
ETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQKVANKVFETVAMAKVSTSGQ
HHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCH
EAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
HHHHHCCCCCCCCCEECCCEEEEECHHHHHHHHHCCCCCCCHHCCCEECCCCCEEEEECC
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MQHMLVKGKPLRN
HHHHHHCCCCCCC
>Mature Secondary Structure
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRF
CCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCHHCCCCEEEHHHHHHHH
SNTAVQKLLKQKPAPLTVKGNLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEK
HHHHHHHHHHCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHFFNPPRYLKLLEVIPTKKTDP
HHHHCCCCCEEECCCCCCCHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCH
QVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGP
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTG
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QGFFLKQGKEILELNPETMEYEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLW
CCEEHHCCCHHHHCCCHHHHHHHHHHHHHHHEEHHHHHCCHHHHHHEEEEECCCHHHHHH
NIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFEVWDAIGVEKSVQKMEESGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCC
IPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIERNKKAISLKQLKAKNGVLKKNSGA
CHHHHHHHHHCCCCEEEEECCCCCEEEECCCEEEEECCCHHHHHHHHHHHCCCEECCCCC
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAM
CEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCEEE
ILMEAQDDNYFEIEWVVKNFQDAMTKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASS
EEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEECCCCEEECCCCCEEEECHHCCCCC
ETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQKVANKVFETVAMAKVSTSGQ
HHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCH
EAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGA
HHHHHCCCCCCCCCEECCCEEEEECHHHHHHHHHCCCCCCCHHCCCEECCCCCEEEEECC
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MQHMLVKGKPLRN
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]