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The map label for this gene is hflx

Identifier: 49479206

GI number: 49479206

Start: 3535749

End: 3537026

Strand: Reverse

Name: hflx

Synonym: BT9727_3452

Alternate gene names: 49479206

Gene position: 3537026-3535749 (Counterclockwise)

Preceding gene: 49478335

Following gene: 49480845

Centisome position: 67.53

GC content: 36.62

Gene sequence:

>1278_bases
TTGATGGAAGAAAAAGAAAAAGTCATATTAGTGGGCTGTCAATTGCCGCAAGATGATGATGAAAAGTTTATGCATTCCAT
GAAAGAGCTTGCATCGCTAGCGAAGACTGCACGAGCAGAATTGTTAGTGTCTACAACGCAAAAACGACCGAAGTTTCATC
CGGCGACTTATATCGGTAAAGGTAAATTAGAAGAGCTTACCATGTTAACTGAAGAATTAGAACCGGATGTTATCGTATTT
AATAACGAATTAACACCGAGTCAAATTCGGAATTTATCCTCAGTATTAGATGCGAGGGTAATTGATCGAACGCAACTCAT
ATTAGATATTTTTGCGCAACGTGCGAAATCGAGAGAAGGGAAGCTTCAAGTAGAATTAGCTCAGTTGCAATATACAATGC
CGCGTCTTATGGGACAAGGATTGTCTTTATCACGTCTTGGTGGTGGTATTGGAACGAGAGGGCCGGGTGAAACGAAGCTT
GAGACGGACCGTCGTCATATTCGATCACGCATTGATGAAATAAAGAAACAACTTGCGGTTGTTGTGGAACATCGAAAAAG
ATATCGTGAGAGAAGAAAAGATAATAAAGTATTTCAAGTTTCGTTAATAGGATATACGAATGCGGGAAAATCTACACTGT
TTAATAGATTAACGGAAGCCGATACATTTGAAGAAAACTTGTTGTTTGCAACACTAGACCCGACAACAAGGAAGATGCCG
CTACCTTCTGGTTATACAGTATTACTAACTGATACAGTTGGTTTTATACAAGATTTACCTACGTCATTAATTGCTGCATT
CCGTTCGACGTTAGAAGAAGCTGGTGAAGCGGATGTTATTTTACATGTTGTGGATTCTGCAGATCCTAATTATGTAGGGC
ATGAGAAAACAGTAAAACAATTATTGTCAGAACTCGAAATTAATCATATTCCTATTATTACGTTATATAATAAAAAAGAT
GAATTACATCAAAACTTTATTCCGTTTCCGAAAAATGACTTCTTAATGACTAGTGCTTTTGAAGAAAAGGATCTATTACA
TATAAAAGAAGCGATAGAAACGAAAATGAAGGAAGAAATGAATCGTTATCAAGTGGAGATTCCTCCGAGTGAAGGTAAGT
TGTTAACGTTACTAAAGACGGAGACGCTATTAACGAAGATGGAGTTTTTGGAAGATAAATTTGTATATGATTGCGCAGGG
TATATTTTTGCTCATTCATCACTTAATGTGCAATTAAAGAGATTTTTAGTGGAAGAAGGAGAAAATAAAAATGTTTGA

Upstream 100 bases:

>100_bases
TCCCATGCCATGAATTTTCTCCCCCGCTAACTAGATGAAATGTGCTTCCTCTGCTATTATATTAGAAGGTTTAAATTTCG
AAAAGGATGAGTGAACATAT

Downstream 100 bases:

>100_bases
TCGTTTGAAAAATGGAGAAAAGATTGCTCCGATTGTAAAAGAAGTAGAGAGCCAAATTACAGAAGTACATAAACGTGCGG
ATGAAGTTATTGAAAGTAAT

Product: GTP-binding protein (hflX)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MMEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGKGKLEELTMLTEELEPDVIVF
NNELTPSQIRNLSSVLDARVIDRTQLILDIFAQRAKSREGKLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKL
ETDRRHIRSRIDEIKKQLAVVVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMP
LPSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKQLLSELEINHIPIITLYNKKD
ELHQNFIPFPKNDFLMTSAFEEKDLLHIKEAIETKMKEEMNRYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYDCAG
YIFAHSSLNVQLKRFLVEEGENKNV

Sequences:

>Translated_425_residues
MMEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGKGKLEELTMLTEELEPDVIVF
NNELTPSQIRNLSSVLDARVIDRTQLILDIFAQRAKSREGKLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKL
ETDRRHIRSRIDEIKKQLAVVVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMP
LPSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKQLLSELEINHIPIITLYNKKD
ELHQNFIPFPKNDFLMTSAFEEKDLLHIKEAIETKMKEEMNRYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYDCAG
YIFAHSSLNVQLKRFLVEEGENKNV
>Mature_425_residues
MMEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGKGKLEELTMLTEELEPDVIVF
NNELTPSQIRNLSSVLDARVIDRTQLILDIFAQRAKSREGKLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKL
ETDRRHIRSRIDEIKKQLAVVVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMP
LPSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKQLLSELEINHIPIITLYNKKD
ELHQNFIPFPKNDFLMTSAFEEKDLLHIKEAIETKMKEEMNRYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYDCAG
YIFAHSSLNVQLKRFLVEEGENKNV

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=145, Percent_Identity=39.3103448275862, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI310133118, Length=239, Percent_Identity=31.7991631799163, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI310124269, Length=137, Percent_Identity=40.1459854014599, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310124267, Length=137, Percent_Identity=40.1459854014599, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310124171, Length=137, Percent_Identity=40.1459854014599, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310124169, Length=137, Percent_Identity=40.1459854014599, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1790615, Length=375, Percent_Identity=42.1333333333333, Blast_Score=278, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=285, Percent_Identity=32.6315789473684, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24650079, Length=285, Percent_Identity=35.0877192982456, Blast_Score=125, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48541; Mature: 48541

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGK
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECC
GKLEELTMLTEELEPDVIVFNNELTPSQIRNLSSVLDARVIDRTQLILDIFAQRAKSREG
CCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLETDRRHIRSRIDEIKKQLAV
CEEEEHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMP
HHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCHHCCEEEEEECCCCCCCC
LPSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKQ
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHH
LLSELEINHIPIITLYNKKDELHQNFIPFPKNDFLMTSAFEEKDLLHIKEAIETKMKEEM
HHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
NRYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYDCAGYIFAHSSLNVQLKRFLVEEG
HHEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
ENKNV
CCCCC
>Mature Secondary Structure
MMEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGK
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECC
GKLEELTMLTEELEPDVIVFNNELTPSQIRNLSSVLDARVIDRTQLILDIFAQRAKSREG
CCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLETDRRHIRSRIDEIKKQLAV
CEEEEHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMP
HHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCHHCCEEEEEECCCCCCCC
LPSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKQ
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHH
LLSELEINHIPIITLYNKKDELHQNFIPFPKNDFLMTSAFEEKDLLHIKEAIETKMKEEM
HHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
NRYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYDCAGYIFAHSSLNVQLKRFLVEEG
HHEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
ENKNV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]