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The map label for this gene is yqcK [H]

Identifier: 49479113

GI number: 49479113

Start: 3043662

End: 3044099

Strand: Reverse

Name: yqcK [H]

Synonym: BT9727_2965

Alternate gene names: 49479113

Gene position: 3044099-3043662 (Counterclockwise)

Preceding gene: 49479114

Following gene: 49480092

Centisome position: 58.12

GC content: 34.47

Gene sequence:

>438_bases
ATGAGATATGTTCACGTTGGTATAAATGTTACGAATTTAGAGAAGTCTATTGAATTTTACGAAAAATTATTTGGTGTATC
GCCAGTTAAGGTGAAAACGGATTATGCAAAATTTTTATTAGAGACGCCAGGACTTAATTTTACGCTGAACGTACGAGATG
AAGTGAAGGGAAATAAAGTAAATCATTTTGGTTTCCAAGTGGATACAGCTGAAGAAATTACATTACATAAAGAACGATTA
GAAAAAGAAGGTTTCTTCGCGCGTGATGAGATGGATACGACTTGTTGCTATGCGGTTCAAGATAAGTTTTGGGTAACAGA
TCCTGATGGGAATGAGTGGGAATTCTTTTATACGAAAGCACATAGTGATGTTCACAAAATTGAAGAGTCATCTTGTTGTA
CGACTTCTAATGAAGTAGCTAAAAATTCTTGTTGTTAA

Upstream 100 bases:

>100_bases
CTGTATCTTTAGAAAAACAGGCAAAGGGAGCTGCTGTTAAAATTTTGAGTTATTAATCAAAAAAAATTGATTAATGATAT
GTAAAGAGGAGGAATAAGGT

Downstream 100 bases:

>100_bases
TAGGAGATGGAAAATAAAATGAAACGTTTATCTTTTCTAGACCGATATTTAACACTATGGATTTTTCTAGCGATGGCTGT
TGGGATTGGTTTAGGGTTTG

Product: lactoylglutathione lyase, glyoxalase family protein

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MRYVHVGINVTNLEKSIEFYEKLFGVSPVKVKTDYAKFLLETPGLNFTLNVRDEVKGNKVNHFGFQVDTAEEITLHKERL
EKEGFFARDEMDTTCCYAVQDKFWVTDPDGNEWEFFYTKAHSDVHKIEESSCCTTSNEVAKNSCC

Sequences:

>Translated_145_residues
MRYVHVGINVTNLEKSIEFYEKLFGVSPVKVKTDYAKFLLETPGLNFTLNVRDEVKGNKVNHFGFQVDTAEEITLHKERL
EKEGFFARDEMDTTCCYAVQDKFWVTDPDGNEWEFFYTKAHSDVHKIEESSCCTTSNEVAKNSCC
>Mature_145_residues
MRYVHVGINVTNLEKSIEFYEKLFGVSPVKVKTDYAKFLLETPGLNFTLNVRDEVKGNKVNHFGFQVDTAEEITLHKERL
EKEGFFARDEMDTTCCYAVQDKFWVTDPDGNEWEFFYTKAHSDVHKIEESSCCTTSNEVAKNSCC

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2641 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 16754; Mature: 16754

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVHVGINVTNLEKSIEFYEKLFGVSPVKVKTDYAKFLLETPGLNFTLNVRDEVKGNKV
CEEEEEECEEEHHHHHHHHHHHHHCCCCEEEEHHHHHHHEECCCCCEEEEECCCCCCCEE
NHFGFQVDTAEEITLHKERLEKEGFFARDEMDTTCCYAVQDKFWVTDPDGNEWEFFYTKA
EECCEEECCHHHHHHHHHHHHHCCCEECCCCCCEEEEEECCCEEEECCCCCCEEEEEEEC
HSDVHKIEESSCCTTSNEVAKNSCC
CCHHHHHCCCCCCCCCCHHHCCCCC
>Mature Secondary Structure
MRYVHVGINVTNLEKSIEFYEKLFGVSPVKVKTDYAKFLLETPGLNFTLNVRDEVKGNKV
CEEEEEECEEEHHHHHHHHHHHHHCCCCEEEEHHHHHHHEECCCCCEEEEECCCCCCCEE
NHFGFQVDTAEEITLHKERLEKEGFFARDEMDTTCCYAVQDKFWVTDPDGNEWEFFYTKA
EECCEEECCHHHHHHHHHHHHHCCCEECCCCCCEEEEEECCCEEEECCCCCCEEEEEEEC
HSDVHKIEESSCCTTSNEVAKNSCC
CCHHHHHCCCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895 [H]