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The map label for this gene is sigM [H]

Identifier: 49478708

GI number: 49478708

Start: 4419988

End: 4420497

Strand: Reverse

Name: sigM [H]

Synonym: BT9727_4352

Alternate gene names: 49478708

Gene position: 4420497-4419988 (Counterclockwise)

Preceding gene: 49480694

Following gene: 49478707

Centisome position: 84.4

GC content: 34.51

Gene sequence:

>510_bases
ATGAGCCATGATACATTTGAATCGTTATTAATAGAGAAGTCAAAAGCTGTGTTTGGATACTTAATTAAGATTGGAGCAAA
TAGAAAAGAAGCAGAAGATATTGTACAAGATACGTTGTATAAAGCTTTATTGCTTATGGAGGAAATACCGTTAGAACATT
TAACACCGTGGCTCTTTAGAGTTGCGATCAATCAGCACCGAGATTTACACCGAAAAGAAAAAAGACTAAATCCAATTGCG
ATTGAATCTGTCGTTCTTATTGGTCAAAAGTCATTAGATGAAGTGCTTTTAACAAGTGAACTACAAGGCGAGGTACAAGA
AATATTGGAGACGATGACGGAGGAATATCGCCATATTTTACTGTTGAAATATGAATATGAACTGTCTTATAAGGAAATTG
CCATTTTATTAAATATGAAAGAAGAAACAGTGAAAACAAGTTTGTACCGTGCAAGAAATCAATTTAAAAAATTGTACAGG
AGGAGAAACGATGGGGCGGAAGGACTTTGA

Upstream 100 bases:

>100_bases
CACATCAAAATGGATGTGCTTTTTATTATTAAAATTTTTTTAAGAAAAGCTGTATACATTTTACGCTCTCAAACGTTGAG
TATATAGAAAGGAGAGCTAG

Downstream 100 bases:

>100_bases
TTTGAATATGGATGATAAGCAGATGAAGACTTTGATGAAGAAGGCGAAGAGGAAGCAGTTTTGGAGAAATCTAGTAATCT
CAGTAGTTGTGACATTAGTC

Product: ECF subfamily RNA polymerase sigma factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSHDTFESLLIEKSKAVFGYLIKIGANRKEAEDIVQDTLYKALLLMEEIPLEHLTPWLFRVAINQHRDLHRKEKRLNPIA
IESVVLIGQKSLDEVLLTSELQGEVQEILETMTEEYRHILLLKYEYELSYKEIAILLNMKEETVKTSLYRARNQFKKLYR
RRNDGAEGL

Sequences:

>Translated_169_residues
MSHDTFESLLIEKSKAVFGYLIKIGANRKEAEDIVQDTLYKALLLMEEIPLEHLTPWLFRVAINQHRDLHRKEKRLNPIA
IESVVLIGQKSLDEVLLTSELQGEVQEILETMTEEYRHILLLKYEYELSYKEIAILLNMKEETVKTSLYRARNQFKKLYR
RRNDGAEGL
>Mature_168_residues
SHDTFESLLIEKSKAVFGYLIKIGANRKEAEDIVQDTLYKALLLMEEIPLEHLTPWLFRVAINQHRDLHRKEKRLNPIAI
ESVVLIGQKSLDEVLLTSELQGEVQEILETMTEEYRHILLLKYEYELSYKEIAILLNMKEETVKTSLYRARNQFKKLYRR
RNDGAEGL

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt, acid and e

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014296
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 19904; Mature: 19773

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDTFESLLIEKSKAVFGYLIKIGANRKEAEDIVQDTLYKALLLMEEIPLEHLTPWLFR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VAINQHRDLHRKEKRLNPIAIESVVLIGQKSLDEVLLTSELQGEVQEILETMTEEYRHIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LLKYEYELSYKEIAILLNMKEETVKTSLYRARNQFKKLYRRRNDGAEGL
EEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SHDTFESLLIEKSKAVFGYLIKIGANRKEAEDIVQDTLYKALLLMEEIPLEHLTPWLFR
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VAINQHRDLHRKEKRLNPIAIESVVLIGQKSLDEVLLTSELQGEVQEILETMTEEYRHIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LLKYEYELSYKEIAILLNMKEETVKTSLYRARNQFKKLYRRRNDGAEGL
EEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 12775685; 10216858 [H]