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The map label for this gene is isdC [H]

Identifier: 49478684

GI number: 49478684

Start: 4346010

End: 4346735

Strand: Reverse

Name: isdC [H]

Synonym: BT9727_4282

Alternate gene names: 49478684

Gene position: 4346735-4346010 (Counterclockwise)

Preceding gene: 49478816

Following gene: 49481625

Centisome position: 82.99

GC content: 34.3

Gene sequence:

>726_bases
ATGAGAAAGATTTCTGTATTACCCGCTTTTATTATAACGTTCGTATGTATGCTAGCTTTTCTTATCATGCCATATGGGAA
AGTTTCAGCACAACTAGCTGACGGTACTTATGACATTAACTATGTCATTCAAAAAGCGGAGAATGATTCAGCTTCAATGG
CAAATGATTATTTTGAAAAACCAGCTAAGCTAATTGTGAAAAATGGTGAGATGAGAGTACAAATTCCGATGAATCATAGT
GCTTGGATTACAGAATTTAAAGCACCTGAAAACGGGAATTTTGTTGATGCAAAAGTAGTTAGCAAGGACGAGGCTGCTGA
TAAAAGAACGGTTGAATTTAAAATTGATGATTTATCAAAACCATTAGGAGTAAAAATTCATGTTGTCGTACCAAGTGCAA
ACTATGACCACCACTACACAATTCGTTTTGCTTTTGATGCAAATGTACAAGCTGTAGGTGGAGATAACGGCGCGGCTGCT
ATAACAAAAAACAATGATCAAACGAAAACAGGTACACAAGTCAAAGAAGAGAAAACAAAAGTAGAGAATAAAGAAACAAC
AAAAGAAGCGAACAAAGAAACAAATAAAGATACAAAAAATGAAAATGGTAAAGCTGAAAAAACAGATAATCCTAAAACAG
GCGATGAAGCACGTATCGGATTATTTGCGGTGTTAATTCTTATTTCAGGTGTTTTCTTAATTCGTAACGTGAAGTTTAGT
AAATAA

Upstream 100 bases:

>100_bases
AAATAATGATAGAAGATTATTATTTTTTTCTAACAAATTGAGAATAATTATCATTTTCAAAAAATAGGGATGAAAGATAA
ACAAGGAGGAAGTAAGCCAA

Downstream 100 bases:

>100_bases
ATAAAAAGGAGCGTTATTTCATTGAACAGGTATCTTAAGATTGTTGTTGCTATGTTTTTAATGATATTTACATTCGTATC
AACACTACAACCACTTGCAG

Product: cell surface protein, iron transport associated

Products: NA

Alternate protein names: Staphylococcal iron-regulated protein D [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MRKISVLPAFIITFVCMLAFLIMPYGKVSAQLADGTYDINYVIQKAENDSASMANDYFEKPAKLIVKNGEMRVQIPMNHS
AWITEFKAPENGNFVDAKVVSKDEAADKRTVEFKIDDLSKPLGVKIHVVVPSANYDHHYTIRFAFDANVQAVGGDNGAAA
ITKNNDQTKTGTQVKEEKTKVENKETTKEANKETNKDTKNENGKAEKTDNPKTGDEARIGLFAVLILISGVFLIRNVKFS
K

Sequences:

>Translated_241_residues
MRKISVLPAFIITFVCMLAFLIMPYGKVSAQLADGTYDINYVIQKAENDSASMANDYFEKPAKLIVKNGEMRVQIPMNHS
AWITEFKAPENGNFVDAKVVSKDEAADKRTVEFKIDDLSKPLGVKIHVVVPSANYDHHYTIRFAFDANVQAVGGDNGAAA
ITKNNDQTKTGTQVKEEKTKVENKETTKEANKETNKDTKNENGKAEKTDNPKTGDEARIGLFAVLILISGVFLIRNVKFS
K
>Mature_241_residues
MRKISVLPAFIITFVCMLAFLIMPYGKVSAQLADGTYDINYVIQKAENDSASMANDYFEKPAKLIVKNGEMRVQIPMNHS
AWITEFKAPENGNFVDAKVVSKDEAADKRTVEFKIDDLSKPLGVKIHVVVPSANYDHHYTIRFAFDANVQAVGGDNGAAA
ITKNNDQTKTGTQVKEEKTKVENKETTKEANKETNKDTKNENGKAEKTDNPKTGDEARIGLFAVLILISGVFLIRNVKFS
K

Specific function: Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e., mediates the transfer of the iron-containing nutrient from isdABH

COG id: COG5386

COG function: function code M; Cell surface protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 NEAT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019909
- InterPro:   IPR006635
- InterPro:   IPR017505 [H]

Pfam domain/function: PF05031 NEAT [H]

EC number: NA

Molecular weight: Translated: 26722; Mature: 26722

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50978 NEAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKISVLPAFIITFVCMLAFLIMPYGKVSAQLADGTYDINYVIQKAENDSASMANDYFEK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEEEECCCCCHHHHHHHHHC
PAKLIVKNGEMRVQIPMNHSAWITEFKAPENGNFVDAKVVSKDEAADKRTVEFKIDDLSK
CCEEEEECCCEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCC
PLGVKIHVVVPSANYDHHYTIRFAFDANVQAVGGDNGAAAITKNNDQTKTGTQVKEEKTK
CCCEEEEEEEECCCCCCEEEEEEEEECCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHH
VENKETTKEANKETNKDTKNENGKAEKTDNPKTGDEARIGLFAVLILISGVFLIRNVKFS
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
K
C
>Mature Secondary Structure
MRKISVLPAFIITFVCMLAFLIMPYGKVSAQLADGTYDINYVIQKAENDSASMANDYFEK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEEEECCCCCHHHHHHHHHC
PAKLIVKNGEMRVQIPMNHSAWITEFKAPENGNFVDAKVVSKDEAADKRTVEFKIDDLSK
CCEEEEECCCEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCC
PLGVKIHVVVPSANYDHHYTIRFAFDANVQAVGGDNGAAAITKNNDQTKTGTQVKEEKTK
CCCEEEEEEEECCCCCCEEEEEEEEECCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHH
VENKETTKEANKETNKDTKNENGKAEKTDNPKTGDEARIGLFAVLILISGVFLIRNVKFS
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA