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The map label for this gene is argJ

Identifier: 49478552

GI number: 49478552

Start: 3961129

End: 3962355

Strand: Reverse

Name: argJ

Synonym: BT9727_3878

Alternate gene names: 49478552

Gene position: 3962355-3961129 (Counterclockwise)

Preceding gene: 49478553

Following gene: 49478551

Centisome position: 75.65

GC content: 37.25

Gene sequence:

>1227_bases
ATGATGATTAAAATAGCGTCTATTACAAAAGTAGAAAATGGTTCGATTGTAACGCCGAAAGGTTTCTCAGCGATCGGTAC
TGCAATTGGTTTGAAAAAGGAGAAAAAGGATTTAGGGGCAATCGTTTGTGATGTACCGGCATCATGTGCTGCTGTTTATA
CAACAAATCAAATACAAGCAGCCCCGTTGCAAGTAACGAAGGATAGTATAACGACTGAGAGAAAATTACAAGCTATTATC
GTTAATAGTGGAAATGCAAATGCTTGTACAGGAATGAAAGGATTACAAGATGCTTACGAGATGCGTGTATTAGGGGCGGA
ACATTTTGGAGTGAAAGAAAATTACGTTGCAGTAGCTTCAACAGGTGTAATTGGTGTTCCGCTGCCGATGGATATAATCC
GAAAGGGAATTGCAACTCTTATACCAGCGAAGGAAGAAAATGAAGCTCATTCTTTTTCTGAAGCAATCTTAACGACGGAT
CTTATAACGAAAGAAACTTGCTATGAAATGAGTATTGATGGGAAGAAAGTGATGATTGCTGGTGTTGCGAAAGGTTCAGG
GATGATTCATCCAAATATGGCAACGATGCTAAGTTTTATTACGACAGACGCTCATATAGAGCATGACGTATTGCAAACAG
CATTATCACAAATAACGAATCATACATTTAATCAAATTACGGTGGATGGAGATACTTCTACGAATGATATGGTCATTGCT
ATGGCAAGTGGATTATCAGAAACGAAACCAATCAATATGGAACATGCAGATTGGGAAACTTTCGTATTTGCTTTACAGAA
GGTATGTGAAGATTTAGCCAAAAAAATTGCACAAGATGGTGAAGGCGCTACGAAGTTAATAGAAGTAAATGTGCTAGGAG
CTCAAACAAATGAAGAGGCAAAGAAAATCGCAAAGCAAATAGTCGGTTCAAGTCTTGTGAAAACAGCAATACATGGTGAA
GACCCAAATTGGGGGCGAATTATTAGCAGTATTGGACAAAGTGAAGTAGCAATTAATCCGAATACAATTGAAATTACTCT
GCAATCTATAGCGGTATTAAAAAATAGTGAGCCTCAAACATTTTCTGAAGAAGAAATGAAAGAGAGATTACAAGAAGATG
AAATAGTCATTAATGTGTATTTACATTTAGGTGAAGAGACAGGATCAGCTTGGGGCTGTGATTTAAGCTATGAATATGTG
AAAATAAACGCTTGTTATCGTACATAA

Upstream 100 bases:

>100_bases
AAAGGTGCGGCTGGGCAAGCGATTCAAAATGCAAATATAGTAGCGGGACTAGAAGAAACAACAGGTTTACAACATATGCC
GCTTTATTTATAAGGGGGAC

Downstream 100 bases:

>100_bases
GGAGAGGGAAGATGAACGATTATATTGTAGTGAAATGCGGCGGTAGTATGTTGTAGCAATTAAATGATGTGTTTTTTGAT
TGTATAAAGAAATTGCAACA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MMIKIASITKVENGSIVTPKGFSAIGTAIGLKKEKKDLGAIVCDVPASCAAVYTTNQIQAAPLQVTKDSITTERKLQAII
VNSGNANACTGMKGLQDAYEMRVLGAEHFGVKENYVAVASTGVIGVPLPMDIIRKGIATLIPAKEENEAHSFSEAILTTD
LITKETCYEMSIDGKKVMIAGVAKGSGMIHPNMATMLSFITTDAHIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIA
MASGLSETKPINMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGAQTNEEAKKIAKQIVGSSLVKTAIHGE
DPNWGRIISSIGQSEVAINPNTIEITLQSIAVLKNSEPQTFSEEEMKERLQEDEIVINVYLHLGEETGSAWGCDLSYEYV
KINACYRT

Sequences:

>Translated_408_residues
MMIKIASITKVENGSIVTPKGFSAIGTAIGLKKEKKDLGAIVCDVPASCAAVYTTNQIQAAPLQVTKDSITTERKLQAII
VNSGNANACTGMKGLQDAYEMRVLGAEHFGVKENYVAVASTGVIGVPLPMDIIRKGIATLIPAKEENEAHSFSEAILTTD
LITKETCYEMSIDGKKVMIAGVAKGSGMIHPNMATMLSFITTDAHIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIA
MASGLSETKPINMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGAQTNEEAKKIAKQIVGSSLVKTAIHGE
DPNWGRIISSIGQSEVAINPNTIEITLQSIAVLKNSEPQTFSEEEMKERLQEDEIVINVYLHLGEETGSAWGCDLSYEYV
KINACYRT
>Mature_408_residues
MMIKIASITKVENGSIVTPKGFSAIGTAIGLKKEKKDLGAIVCDVPASCAAVYTTNQIQAAPLQVTKDSITTERKLQAII
VNSGNANACTGMKGLQDAYEMRVLGAEHFGVKENYVAVASTGVIGVPLPMDIIRKGIATLIPAKEENEAHSFSEAILTTD
LITKETCYEMSIDGKKVMIAGVAKGSGMIHPNMATMLSFITTDAHIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIA
MASGLSETKPINMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGAQTNEEAKKIAKQIVGSSLVKTAIHGE
DPNWGRIISSIGQSEVAINPNTIEITLQSIAVLKNSEPQTFSEEEMKERLQEDEIVINVYLHLGEETGSAWGCDLSYEYV
KINACYRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=414, Percent_Identity=39.1304347826087, Blast_Score=254, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 44025; Mature: 44025

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIKIASITKVENGSIVTPKGFSAIGTAIGLKKEKKDLGAIVCDVPASCAAVYTTNQIQA
CEEEEEEEEEECCCCEECCCCCHHHHHHHCCCHHHHCCCEEEECCCCCCEEEEECCCEEE
APLQVTKDSITTERKLQAIIVNSGNANACTGMKGLQDAYEMRVLGAEHFGVKENYVAVAS
CCEEEECCHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHEECCHHCCCCCCEEEEEE
TGVIGVPLPMDIIRKGIATLIPAKEENEAHSFSEAILTTDLITKETCYEMSIDGKKVMIA
CCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEE
GVAKGSGMIHPNMATMLSFITTDAHIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIA
EEECCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
MASGLSETKPINMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGAQTNEEA
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHH
KKIAKQIVGSSLVKTAIHGEDPNWGRIISSIGQSEVAINPNTIEITLQSIAVLKNSEPQT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEECCCEEEEEEEEEHHHCCCCCCC
FSEEEMKERLQEDEIVINVYLHLGEETGSAWGCDLSYEYVKINACYRT
CCHHHHHHHHCCCCEEEEEEEEECCCCCCEECCCCEEEEEEEEEEECC
>Mature Secondary Structure
MMIKIASITKVENGSIVTPKGFSAIGTAIGLKKEKKDLGAIVCDVPASCAAVYTTNQIQA
CEEEEEEEEEECCCCEECCCCCHHHHHHHCCCHHHHCCCEEEECCCCCCEEEEECCCEEE
APLQVTKDSITTERKLQAIIVNSGNANACTGMKGLQDAYEMRVLGAEHFGVKENYVAVAS
CCEEEECCHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHEECCHHCCCCCCEEEEEE
TGVIGVPLPMDIIRKGIATLIPAKEENEAHSFSEAILTTDLITKETCYEMSIDGKKVMIA
CCEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEE
GVAKGSGMIHPNMATMLSFITTDAHIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIA
EEECCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
MASGLSETKPINMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGAQTNEEA
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHH
KKIAKQIVGSSLVKTAIHGEDPNWGRIISSIGQSEVAINPNTIEITLQSIAVLKNSEPQT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEECCCEEEEEEEEEHHHCCCCCCC
FSEEEMKERLQEDEIVINVYLHLGEETGSAWGCDLSYEYVKINACYRT
CCHHHHHHHHCCCCEEEEEEEEECCCCCCEECCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]