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The map label for this gene is rraA

Identifier: 49478174

GI number: 49478174

Start: 3178231

End: 3178710

Strand: Reverse

Name: rraA

Synonym: BT9727_3109

Alternate gene names: 49478174

Gene position: 3178710-3178231 (Counterclockwise)

Preceding gene: 49478175

Following gene: 49478173

Centisome position: 60.69

GC content: 38.33

Gene sequence:

>480_bases
ATGTGGAAAACTACGGATTTATGTGATGAGTTTGAAAAGGATTTACAAATATGTCGCCAGTCCTTTCGATCTTTTGGGAA
GAAAGAACAATTCCACGGGAAAATTGCAACGGTGAAAGTGAAGGATGATAATGTACTAGTGAAGGAAGGATTACAAACAT
TGCCGGAAGGAACGGTATTAGTTGTTGACGGGGGAGCCTCTACGAATTGTGCGTTACTTGGTGATAATTTGGCAGCTATT
GCGGAGGAAAGAAAGCTGGCAGGAATTATTGTGAATGGATATGTTCGTGATTCTAGTGAGCTAAAGAATATAAATATAGG
TATTTTAGCGTTAGGAACAATGCCGAATAGAAGTGTTAAAGAAGGAAAAGGAGAACGAAATATTTCATTGCAATTTGGAC
AAGTAGAATGGAAGCCGGATGAATATGTGTATGTGGATGAAGATGGCGTCATTATTAGTGAAAAGAGTTTGCATCGTTAA

Upstream 100 bases:

>100_bases
TTCTTTTCTTACGCATACAAATTCTTGCAACATTAGACAGGGAAACGAAAATAATCCAAGAATATGTTAAATAGAAAATA
AAAGGAAAAGAGGGAAAAAG

Downstream 100 bases:

>100_bases
AGGTTAGTAAGTTACTATTCTTAGAAAATAAATCCGATAAAGCATGGACAAAATTCTTTGTCAATAGTAAAATAATACAG
AAATTTAAAATTAACAGAAT

Product: ribonuclease activity regulator protein RraA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MWKTTDLCDEFEKDLQICRQSFRSFGKKEQFHGKIATVKVKDDNVLVKEGLQTLPEGTVLVVDGGASTNCALLGDNLAAI
AEERKLAGIIVNGYVRDSSELKNINIGILALGTMPNRSVKEGKGERNISLQFGQVEWKPDEYVYVDEDGVIISEKSLHR

Sequences:

>Translated_159_residues
MWKTTDLCDEFEKDLQICRQSFRSFGKKEQFHGKIATVKVKDDNVLVKEGLQTLPEGTVLVVDGGASTNCALLGDNLAAI
AEERKLAGIIVNGYVRDSSELKNINIGILALGTMPNRSVKEGKGERNISLQFGQVEWKPDEYVYVDEDGVIISEKSLHR
>Mature_159_residues
MWKTTDLCDEFEKDLQICRQSFRSFGKKEQFHGKIATVKVKDDNVLVKEGLQTLPEGTVLVVDGGASTNCALLGDNLAAI
AEERKLAGIIVNGYVRDSSELKNINIGILALGTMPNRSVKEGKGERNISLQFGQVEWKPDEYVYVDEDGVIISEKSLHR

Specific function: Regulator Of Rnase E/Rne, Which Inhibits The Endonuclease Activity And Thereby Leads To Increase The Half-Life And Abundance Of Rnas. General Modulator Of RNA Abundance. Does Not Have Any Methyltransferase Activity. [C]

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RraA family [H]

Homologues:

Organism=Escherichia coli, GI1790364, Length=156, Percent_Identity=35.8974358974359, Blast_Score=108, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005493
- InterPro:   IPR010203 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: NA

Molecular weight: Translated: 17642; Mature: 17642

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKTTDLCDEFEKDLQICRQSFRSFGKKEQFHGKIATVKVKDDNVLVKEGLQTLPEGTVL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEHHHHHHHCCCCEEE
VVDGGASTNCALLGDNLAAIAEERKLAGIIVNGYVRDSSELKNINIGILALGTMPNRSVK
EEECCCCCCEEEECCCHHHHHHCCCEEEEEEEEEEECCCCCCCCEEEEEEEECCCCCCHH
EGKGERNISLQFGQVEWKPDEYVYVDEDGVIISEKSLHR
CCCCCCEEEEEECEEEECCCCEEEECCCCEEECCCCCCC
>Mature Secondary Structure
MWKTTDLCDEFEKDLQICRQSFRSFGKKEQFHGKIATVKVKDDNVLVKEGLQTLPEGTVL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEHHHHHHHCCCCEEE
VVDGGASTNCALLGDNLAAIAEERKLAGIIVNGYVRDSSELKNINIGILALGTMPNRSVK
EEECCCCCCEEEECCCHHHHHHCCCEEEEEEEEEEECCCCCCCCEEEEEEEECCCCCCHH
EGKGERNISLQFGQVEWKPDEYVYVDEDGVIISEKSLHR
CCCCCCEEEEEECEEEECCCCEEEECCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]