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The map label for this gene is sigM

Identifier: 49478105

GI number: 49478105

Start: 3108814

End: 3109314

Strand: Reverse

Name: sigM

Synonym: BT9727_3026

Alternate gene names: 49478105

Gene position: 3109314-3108814 (Counterclockwise)

Preceding gene: 49479506

Following gene: 49478104

Centisome position: 59.36

GC content: 32.93

Gene sequence:

>501_bases
ATGGAAATTGAAGAAATATATAAGGTTTATATAAACGATGTGTATCGGTATTTATTTTCCCTTTCTCGTAGCCATCATGT
AGCGGAGGACTTGATGCAGGAGACTTTTTATCGGGCGTATCTTTATCTAGAAGATTATGAAAATCAAAAGGTAAAATCAT
GGCTTTTTAAAGTGGCGTATCATACGTTTATTGATTTTGTTAGGAAAGAGAGAAAAGTGTCTTTTGTAGGAACGGAGGAA
TTAGAGACAATACAAGCCGGTGAATCTACAGAAGAGTATGTAGTCGCAAAAAATAGTTACGAAAAATTAATTCAGATTAT
TCATACTTTACCTGTGATAGAGGCGCAAGCTATTTTATTATGTGACGTACATGAATTAACGTACGAAGAGGGTGCTTCTG
TATTAGATTTAAAGTTAAACACGTATAAAAGTCACATATTTCGTGGGAGAAAAAGATTAAAACAATTATTAAAGGAGGAA
AAGAGTCAAAATGACAAATGA

Upstream 100 bases:

>100_bases
TTAGAATGTTAAGGGTTATTTTTTTATAAAAAAAGAAAAAGGAAAAATAATGCAACTTTTTAACGCGCTTATTCGTGTTA
TATATGAAAGGAGGAGGGGA

Downstream 100 bases:

>100_bases
TAAACCTCATTCTGAACAAGAAGATTATAAAGACTTGTTGCAAGAAGCTCTTCATCAAAGGCCTGCATCTCTTCCTGATG
GAAAACAGGAGCAAGTGTTG

Product: RNA polymerase sigma factor SigM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MEIEEIYKVYINDVYRYLFSLSRSHHVAEDLMQETFYRAYLYLEDYENQKVKSWLFKVAYHTFIDFVRKERKVSFVGTEE
LETIQAGESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEGASVLDLKLNTYKSHIFRGRKRLKQLLKEE
KSQNDK

Sequences:

>Translated_166_residues
MEIEEIYKVYINDVYRYLFSLSRSHHVAEDLMQETFYRAYLYLEDYENQKVKSWLFKVAYHTFIDFVRKERKVSFVGTEE
LETIQAGESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEGASVLDLKLNTYKSHIFRGRKRLKQLLKEE
KSQNDK
>Mature_166_residues
MEIEEIYKVYINDVYRYLFSLSRSHHVAEDLMQETFYRAYLYLEDYENQKVKSWLFKVAYHTFIDFVRKERKVSFVGTEE
LETIQAGESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEGASVLDLKLNTYKSHIFRGRKRLKQLLKEE
KSQNDK

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt, acid and e

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014296
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 19845; Mature: 19845

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIEEIYKVYINDVYRYLFSLSRSHHVAEDLMQETFYRAYLYLEDYENQKVKSWLFKVAY
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HTFIDFVRKERKVSFVGTEELETIQAGESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILL
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHH
CDVHELTYEEGASVLDLKLNTYKSHIFRGRKRLKQLLKEEKSQNDK
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEIEEIYKVYINDVYRYLFSLSRSHHVAEDLMQETFYRAYLYLEDYENQKVKSWLFKVAY
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HTFIDFVRKERKVSFVGTEELETIQAGESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILL
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHH
CDVHELTYEEGASVLDLKLNTYKSHIFRGRKRLKQLLKEEKSQNDK
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 12775685; 10216858 [H]