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The map label for this gene is arsC

Identifier: 49478069

GI number: 49478069

Start: 3042172

End: 3042576

Strand: Reverse

Name: arsC

Synonym: BT9727_2963

Alternate gene names: 49478069

Gene position: 3042576-3042172 (Counterclockwise)

Preceding gene: 49480092

Following gene: 49479519

Centisome position: 58.09

GC content: 39.75

Gene sequence:

>405_bases
ATGGAGAACAAAAAGACAATCTACTTTTTATGTACAGGAAATTCATGCCGAAGCCAAATGGCAGAAGCATGGGGCAAACA
ATATTTGGGAGATAAGTGGAATGTGTATTCTGCAGGAATCGAAGCACATGGAGTAAATCCAAACGCAATTAAAGCAATGA
ACGAAGTAAATATCGACATAACGAATCAAACATCAGATATAATTGATGCAAACATTTTAAATCGTGCTGATTTAGTCGTT
ACGCTTTGTAGTCATGCGGATTCGGTTTGTCCATCTACTCCGCCGCATGTGAATCGTGTTCACTGGGGATTTGATGATCC
AGCAGGAAAAGAATGGTCGGAATTTCAACGTGTTCGCGATGAAATTGGTGAACGTATAAAGTGCTTTTCTGAAACAGGGG
AGTAA

Upstream 100 bases:

>100_bases
TACCTGTCATGATTGCACTTGTAAACGTTGCTTTTTGGTTTAAACGTAAATATTTTAATGATCAATCAGTCTAAATTTAA
AAATAAAGGTGGAAAACAAC

Downstream 100 bases:

>100_bases
ATAAAGGAAAGAGTCAATCTTCTATTGTGTTGGAGATTGGCTCTTTTTTATTATATATTTCATTGGTTTAAAACAACTAT
TAAAAGGAATAGAGAATATT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase 2; Arsenical pump modifier 2; Low molecular weight protein-tyrosine-phosphatase 2 [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEAHGVNPNAIKAMNEVNIDITNQTSDIIDANILNRADLVV
TLCSHADSVCPSTPPHVNRVHWGFDDPAGKEWSEFQRVRDEIGERIKCFSETGE

Sequences:

>Translated_134_residues
MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEAHGVNPNAIKAMNEVNIDITNQTSDIIDANILNRADLVV
TLCSHADSVCPSTPPHVNRVHWGFDDPAGKEWSEFQRVRDEIGERIKCFSETGE
>Mature_134_residues
MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEAHGVNPNAIKAMNEVNIDITNQTSDIIDANILNRADLVV
TLCSHADSVCPSTPPHVNRVHWGFDDPAGKEWSEFQRVRDEIGERIKCFSETGE

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15019; Mature: 15019

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEAHGVNPNAIKAMNEVNIDI
CCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCEEECCCCHHHHHHHHHCCEEE
TNQTSDIIDANILNRADLVVTLCSHADSVCPSTPPHVNRVHWGFDDPAGKEWSEFQRVRD
CCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHH
EIGERIKCFSETGE
HHHHHHHHHHCCCC
>Mature Secondary Structure
MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEAHGVNPNAIKAMNEVNIDI
CCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCEEECCCCHHHHHHHHHCCEEE
TNQTSDIIDANILNRADLVVTLCSHADSVCPSTPPHVNRVHWGFDDPAGKEWSEFQRVRD
CCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHH
EIGERIKCFSETGE
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA