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The map label for this gene is htpX

Identifier: 49476252

GI number: 49476252

Start: 1844989

End: 1846026

Strand: Reverse

Name: htpX

Synonym: BH16000

Alternate gene names: 49476252

Gene position: 1846026-1844989 (Counterclockwise)

Preceding gene: 49476254

Following gene: 49476251

Centisome position: 95.6

GC content: 43.06

Gene sequence:

>1038_bases
ATGAACATAATGCGTACAGCAATGCTTTTGGCTTTTATGACTGCTCTTTTCATGGGAGTTGGTTATCTGGTTGGCGGAAG
CAATGGCATGGTCATCGCACTTTTGATGGCTGGTGGCTTAAACTTTTTTTCTTATTGGAATTCGGATAAAATCGTTCTAC
GCATGTATGGTGCACGTGAAGTCGATCAACATTCGTCTCCCGTTTATTATAAGATTGTAAGCGATTTAGCGCGAAGAGCT
TCTCTTCCTCAACCAAAAGTTTATATTATTGATAATGCACAGCCAAATGCTTTTGCTACAGGACGTAATCCTCAGAATGC
AGCTGTTGCTGCAAGTACTGGATTGCTAAATCAGTTGAGTGCAGAAGAAGTGGCTGGAGTGATGGCGCATGAGCTTGCTC
ATATTGAGCATCGTGATACGTTAACGATGACTTTGACTGCAACGATTGCCGGGGCAATTTCAATGCTTGGTAATTTCGCT
TTTTTTATGGGGGGACAGCGTCATTCTTCTGAAAATTCTCATAGTACTGGGGCAATCGGAGGACTTCTTGCCCTGTTTGT
AGCACCTTTTGCTGCAATGCTGGTGCAAATGGCCATTAGTCGCACCCGTGAATATGCTGCTGATAGGCGAGGGGCTGAAA
TATGCGGAAATCCTTTATGGTTGGCTTCAGCATTGAGTAAAATTGCAGGTGGGGGGCATACGGTATACAATGAAGAGGCA
GAACATAATCCGGCAACAGCACATATGTTTATTATCAATCCTTTGCGTGGTGAAGGGGCCGATAGTCTTTTTTCTACCCA
TCCCGCAACAGCAAATCGTATTGCTGCTCTTCGTCGGCAAGCAGAAGAGATGAAAGGAGCAAGAGTGGAAAATATGGGAT
GGAATGAAAAAATTGGTTTACATAAAAAAAGCAGTGACTTTAGAGATTTGAATTCTGGTGCGCAAACAAGTGTCTTTAAC
GAAGAAAGTACTGTTCAGCGTATTAAAAAACGCCCTTCTTGGCTTCGTTATGGAGATTCAAAGAGACCTCGATCATAA

Upstream 100 bases:

>100_bases
AGTCTTTTTTATCCATTTTATACCTTTCTTCATTGAAGAAGTAAAAAGAAAACCCCATCATATAGAATTAATAGTATTTT
ATCATGGAGTTTTTTGAGTC

Downstream 100 bases:

>100_bases
AGTTCTTCAGGGGATAAAGACATAAAGGTGTTGTTTTAAAACACGGGAAAGCGGGGCCTATGTCCGAAAAAAATGTTCCA
GGATTAGCTGTCCGGCAGGT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNIMRTAMLLAFMTALFMGVGYLVGGSNGMVIALLMAGGLNFFSYWNSDKIVLRMYGAREVDQHSSPVYYKIVSDLARRA
SLPQPKVYIIDNAQPNAFATGRNPQNAAVAASTGLLNQLSAEEVAGVMAHELAHIEHRDTLTMTLTATIAGAISMLGNFA
FFMGGQRHSSENSHSTGAIGGLLALFVAPFAAMLVQMAISRTREYAADRRGAEICGNPLWLASALSKIAGGGHTVYNEEA
EHNPATAHMFIINPLRGEGADSLFSTHPATANRIAALRRQAEEMKGARVENMGWNEKIGLHKKSSDFRDLNSGAQTSVFN
EESTVQRIKKRPSWLRYGDSKRPRS

Sequences:

>Translated_345_residues
MNIMRTAMLLAFMTALFMGVGYLVGGSNGMVIALLMAGGLNFFSYWNSDKIVLRMYGAREVDQHSSPVYYKIVSDLARRA
SLPQPKVYIIDNAQPNAFATGRNPQNAAVAASTGLLNQLSAEEVAGVMAHELAHIEHRDTLTMTLTATIAGAISMLGNFA
FFMGGQRHSSENSHSTGAIGGLLALFVAPFAAMLVQMAISRTREYAADRRGAEICGNPLWLASALSKIAGGGHTVYNEEA
EHNPATAHMFIINPLRGEGADSLFSTHPATANRIAALRRQAEEMKGARVENMGWNEKIGLHKKSSDFRDLNSGAQTSVFN
EESTVQRIKKRPSWLRYGDSKRPRS
>Mature_345_residues
MNIMRTAMLLAFMTALFMGVGYLVGGSNGMVIALLMAGGLNFFSYWNSDKIVLRMYGAREVDQHSSPVYYKIVSDLARRA
SLPQPKVYIIDNAQPNAFATGRNPQNAAVAASTGLLNQLSAEEVAGVMAHELAHIEHRDTLTMTLTATIAGAISMLGNFA
FFMGGQRHSSENSHSTGAIGGLLALFVAPFAAMLVQMAISRTREYAADRRGAEICGNPLWLASALSKIAGGGHTVYNEEA
EHNPATAHMFIINPLRGEGADSLFSTHPATANRIAALRRQAEEMKGARVENMGWNEKIGLHKKSSDFRDLNSGAQTSVFN
EESTVQRIKKRPSWLRYGDSKRPRS

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family

Homologues:

Organism=Escherichia coli, GI1788133, Length=265, Percent_Identity=33.2075471698113, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HTPX_BARHE (Q6G5S9)

Other databases:

- EMBL:   BX897699
- RefSeq:   YP_034293.1
- ProteinModelPortal:   Q6G5S9
- SMR:   Q6G5S9
- MEROPS:   M48.004
- GeneID:   2865087
- GenomeReviews:   BX897699_GR
- KEGG:   bhe:BH16000
- NMPDR:   fig|283166.1.peg.1421
- HOGENOM:   HBG739460
- OMA:   RRGAEIC
- PhylomeDB:   Q6G5S9
- ProtClustDB:   PRK01345
- BioCyc:   BHEN283166:BH16000-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_00188
- InterPro:   IPR022919
- InterPro:   IPR001915

Pfam domain/function: PF01435 Peptidase_M48

EC number: 3.4.24.-

Molecular weight: Translated: 37508; Mature: 37508

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 131-131

Signals:

None

Transmembrane regions:

HASH(0xda30720)-; HASH(0x403a3d4c)-; HASH(0x403a3d88)-; HASH(0x403a401c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIMRTAMLLAFMTALFMGVGYLVGGSNGMVIALLMAGGLNFFSYWNSDKIVLRMYGARE
CCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEHHHCCCHHHHHCCCCEEEEEECCCCH
VDQHSSPVYYKIVSDLARRASLPQPKVYIIDNAQPNAFATGRNPQNAAVAASTGLLNQLS
HCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHH
AEEVAGVMAHELAHIEHRDTLTMTLTATIAGAISMLGNFAFFMGGQRHSSENSHSTGAIG
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
GLLALFVAPFAAMLVQMAISRTREYAADRRGAEICGNPLWLASALSKIAGGGHTVYNEEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHCCCCCEEECCCC
EHNPATAHMFIINPLRGEGADSLFSTHPATANRIAALRRQAEEMKGARVENMGWNEKIGL
CCCCCEEEEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCC
HKKSSDFRDLNSGAQTSVFNEESTVQRIKKRPSWLRYGDSKRPRS
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCH
>Mature Secondary Structure
MNIMRTAMLLAFMTALFMGVGYLVGGSNGMVIALLMAGGLNFFSYWNSDKIVLRMYGARE
CCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEHHHCCCHHHHHCCCCEEEEEECCCCH
VDQHSSPVYYKIVSDLARRASLPQPKVYIIDNAQPNAFATGRNPQNAAVAASTGLLNQLS
HCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHH
AEEVAGVMAHELAHIEHRDTLTMTLTATIAGAISMLGNFAFFMGGQRHSSENSHSTGAIG
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
GLLALFVAPFAAMLVQMAISRTREYAADRRGAEICGNPLWLASALSKIAGGGHTVYNEEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHCCCCCEEECCCC
EHNPATAHMFIINPLRGEGADSLFSTHPATANRIAALRRQAEEMKGARVENMGWNEKIGL
CCCCCEEEEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCC
HKKSSDFRDLNSGAQTSVFNEESTVQRIKKRPSWLRYGDSKRPRS
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA