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The map label for this gene is sun2 [H]

Identifier: 49476251

GI number: 49476251

Start: 1843586

End: 1844929

Strand: Reverse

Name: sun2 [H]

Synonym: BH15990

Alternate gene names: 49476251

Gene position: 1844929-1843586 (Counterclockwise)

Preceding gene: 49476252

Following gene: 49476250

Centisome position: 95.54

GC content: 43.68

Gene sequence:

>1344_bases
ATGTCCGAAAAAAATGTTCCAGGATTAGCTGTCCGGCAGGTGTCTGTTCGTCTTTTAGGGGTGGTGCTTGATAAAAAGAC
CTCTCTTTCTGGTTTGACGGATAATGAATATGGACATCCACAATATTTAGGGCTTTCACAGCGAGATCGTTTGTTGTGTC
GTGCTATTTTGGCTGCGGCGTTGCGGCATCGGGGGCAGATTACAGATGCTTTAAGGCGCTTTTTGAAAAGGCCTTTGCCT
TCACAAGCACTTTCACTTCAGCATCTTTTGCATATCAGTGCGGCGCAAATTCTTTACCTTGATATTCCTGATCATGCGGC
CATTGATTTAGCTGTGCGTGTGGCAAAACTTGATCCGCGTATGTGTCGTTTTTCAGGGGGAGTGAATGCTCTTTTACGCA
ATGTTGCACGTGAGGCAGTATTTTTACGCCAGAAAGCTCCTCATATTGAAGGCATTCCGGTATGGTTTGGACAGCTTTTA
GTGTCAACTTATGGAAAAGAAAAAACAGAGCAGATTTTAGAAATTCAAAGTGCCCCACCTCCTCTTGATTTGACAGTTAA
ATCCGATAGTCGTGGATGGGCAGAACGGTTGGGGGGTGTTGTTTTGCCCAATGGTTCGGTTCGGTTGAGTCGTTTAGAGG
GTTCTGTTTCTGAATTACCAGGCTATATGGAAGGGGCTTGGTGGATTCAAGATTTTGCTGCCTCATTGCCTGCTTGTTTA
CTCGGAAATATTCATGGTAAACAGGTTGCTGATCTTTGTGCAAGCCCCGGAGGAAAAACAGCACAACTAGCTTTGCAAGG
GGCTGATGTGACAGCAATTGAACTCTCTGCTAATCGGCTAAAACGCTTGAAGGAAAATATGGAGCGACTTCATTTTTCAG
TTCGCTGCTGTGAGGGGGATGTGAAAAATTTTCATCCTAAACAGCTTTTTGATGCTGTGCTTCTTGATGCTCCTTGTTCT
TCTACAGGAACAATACGTCGTCATCCGGATATTTTATGGACGAAATCGATGAACGATGTCATCAAATTAGCGGCGTTGCA
ATATGATCTACTTGTCGCAGCTATTGCTTTGTTGAAGAAAGGAGGGCGCATTGTTTTTTCCAATTGTTCATTGGCAAAAG
AAGAAGGGGAAGATCTCATTACAAGAATTTTATCAGAACGTGGTGACATTGTTTTAGAGCCTATCCTTGCAGAGGAAATG
GGTGTTATGGCGCATTTGCTCTCCGTTGAGGGCATTTTGCGCACAACACCTGCAGATTTTTGTCATGAAAATTTTGACGC
CGAGAAAAATATTTTTTTAGGAATGGATGGTTTTTTTGCAGCGCGCTTGCGAAAAGTGGCTTAA

Upstream 100 bases:

>100_bases
CTTGGCTTCGTTATGGAGATTCAAAGAGACCTCGATCATAAAGTTCTTCAGGGGATAAAGACATAAAGGTGTTGTTTTAA
AACACGGGAAAGCGGGGCCT

Downstream 100 bases:

>100_bases
TTAACGGTTCATTTACTAAAATGGCTGAAATTGTGCTTGATTCAGCACAAATGGAGATAAGATTGTGGCGATTGCGGTAA
AAGGTCCTCAGATAAAGGCA

Product: SUN protein (Fmu protein)

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSEKNVPGLAVRQVSVRLLGVVLDKKTSLSGLTDNEYGHPQYLGLSQRDRLLCRAILAAALRHRGQITDALRRFLKRPLP
SQALSLQHLLHISAAQILYLDIPDHAAIDLAVRVAKLDPRMCRFSGGVNALLRNVAREAVFLRQKAPHIEGIPVWFGQLL
VSTYGKEKTEQILEIQSAPPPLDLTVKSDSRGWAERLGGVVLPNGSVRLSRLEGSVSELPGYMEGAWWIQDFAASLPACL
LGNIHGKQVADLCASPGGKTAQLALQGADVTAIELSANRLKRLKENMERLHFSVRCCEGDVKNFHPKQLFDAVLLDAPCS
STGTIRRHPDILWTKSMNDVIKLAALQYDLLVAAIALLKKGGRIVFSNCSLAKEEGEDLITRILSERGDIVLEPILAEEM
GVMAHLLSVEGILRTTPADFCHENFDAEKNIFLGMDGFFAARLRKVA

Sequences:

>Translated_447_residues
MSEKNVPGLAVRQVSVRLLGVVLDKKTSLSGLTDNEYGHPQYLGLSQRDRLLCRAILAAALRHRGQITDALRRFLKRPLP
SQALSLQHLLHISAAQILYLDIPDHAAIDLAVRVAKLDPRMCRFSGGVNALLRNVAREAVFLRQKAPHIEGIPVWFGQLL
VSTYGKEKTEQILEIQSAPPPLDLTVKSDSRGWAERLGGVVLPNGSVRLSRLEGSVSELPGYMEGAWWIQDFAASLPACL
LGNIHGKQVADLCASPGGKTAQLALQGADVTAIELSANRLKRLKENMERLHFSVRCCEGDVKNFHPKQLFDAVLLDAPCS
STGTIRRHPDILWTKSMNDVIKLAALQYDLLVAAIALLKKGGRIVFSNCSLAKEEGEDLITRILSERGDIVLEPILAEEM
GVMAHLLSVEGILRTTPADFCHENFDAEKNIFLGMDGFFAARLRKVA
>Mature_446_residues
SEKNVPGLAVRQVSVRLLGVVLDKKTSLSGLTDNEYGHPQYLGLSQRDRLLCRAILAAALRHRGQITDALRRFLKRPLPS
QALSLQHLLHISAAQILYLDIPDHAAIDLAVRVAKLDPRMCRFSGGVNALLRNVAREAVFLRQKAPHIEGIPVWFGQLLV
STYGKEKTEQILEIQSAPPPLDLTVKSDSRGWAERLGGVVLPNGSVRLSRLEGSVSELPGYMEGAWWIQDFAASLPACLL
GNIHGKQVADLCASPGGKTAQLALQGADVTAIELSANRLKRLKENMERLHFSVRCCEGDVKNFHPKQLFDAVLLDAPCSS
TGTIRRHPDILWTKSMNDVIKLAALQYDLLVAAIALLKKGGRIVFSNCSLAKEEGEDLITRILSERGDIVLEPILAEEMG
VMAHLLSVEGILRTTPADFCHENFDAEKNIFLGMDGFFAARLRKVA

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=245, Percent_Identity=31.8367346938775, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI76150623, Length=245, Percent_Identity=31.8367346938775, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI32698918, Length=197, Percent_Identity=31.9796954314721, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI11545785, Length=205, Percent_Identity=31.219512195122, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI23199998, Length=220, Percent_Identity=32.2727272727273, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI8922322, Length=220, Percent_Identity=32.2727272727273, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI270288818, Length=215, Percent_Identity=33.0232558139535, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI270288816, Length=215, Percent_Identity=33.0232558139535, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI40316918, Length=228, Percent_Identity=28.5087719298246, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI2367212, Length=402, Percent_Identity=29.6019900497512, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87081985, Length=241, Percent_Identity=33.6099585062241, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17536757, Length=246, Percent_Identity=28.8617886178862, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71998419, Length=168, Percent_Identity=32.7380952380952, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17509941, Length=164, Percent_Identity=29.2682926829268, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115534021, Length=168, Percent_Identity=32.7380952380952, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324268, Length=245, Percent_Identity=30.6122448979592, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319447, Length=183, Percent_Identity=28.9617486338798, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI22024126, Length=240, Percent_Identity=32.5, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355201, Length=180, Percent_Identity=30, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19920494, Length=201, Percent_Identity=24.3781094527363, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 49118; Mature: 48987

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKNVPGLAVRQVSVRLLGVVLDKKTSLSGLTDNEYGHPQYLGLSQRDRLLCRAILAAA
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHH
LRHRGQITDALRRFLKRPLPSQALSLQHLLHISAAQILYLDIPDHAAIDLAVRVAKLDPR
HHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCH
MCRFSGGVNALLRNVAREAVFLRQKAPHIEGIPVWFGQLLVSTYGKEKTEQILEIQSAPP
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCC
PLDLTVKSDSRGWAERLGGVVLPNGSVRLSRLEGSVSELPGYMEGAWWIQDFAASLPACL
CEEEEEECCCCHHHHHCCCEEECCCCEEEEECCCCHHHCCCHHHHHHHHHHHHHHCHHHH
LGNIHGKQVADLCASPGGKTAQLALQGADVTAIELSANRLKRLKENMERLHFSVRCCEGD
HCCCCHHHHHHHHCCCCCCEEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHEEECCCC
VKNFHPKQLFDAVLLDAPCSSTGTIRRHPDILWTKSMNDVIKLAALQYDLLVAAIALLKK
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHC
GGRIVFSNCSLAKEEGEDLITRILSERGDIVLEPILAEEMGVMAHLLSVEGILRTTPADF
CCEEEEECCCCCHHCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCHHH
CHENFDAEKNIFLGMDGFFAARLRKVA
HHCCCCCCCCEEEECCHHHHHHHHHCC
>Mature Secondary Structure 
SEKNVPGLAVRQVSVRLLGVVLDKKTSLSGLTDNEYGHPQYLGLSQRDRLLCRAILAAA
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHH
LRHRGQITDALRRFLKRPLPSQALSLQHLLHISAAQILYLDIPDHAAIDLAVRVAKLDPR
HHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCH
MCRFSGGVNALLRNVAREAVFLRQKAPHIEGIPVWFGQLLVSTYGKEKTEQILEIQSAPP
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCC
PLDLTVKSDSRGWAERLGGVVLPNGSVRLSRLEGSVSELPGYMEGAWWIQDFAASLPACL
CEEEEEECCCCHHHHHCCCEEECCCCEEEEECCCCHHHCCCHHHHHHHHHHHHHHCHHHH
LGNIHGKQVADLCASPGGKTAQLALQGADVTAIELSANRLKRLKENMERLHFSVRCCEGD
HCCCCHHHHHHHHCCCCCCEEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHEEECCCC
VKNFHPKQLFDAVLLDAPCSSTGTIRRHPDILWTKSMNDVIKLAALQYDLLVAAIALLKK
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHC
GGRIVFSNCSLAKEEGEDLITRILSERGDIVLEPILAEEMGVMAHLLSVEGILRTTPADF
CCEEEEECCCCCHHCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCHHH
CHENFDAEKNIFLGMDGFFAARLRKVA
HHCCCCCCCCEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA