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The map label for this gene is glmM

Identifier: 49476133

GI number: 49476133

Start: 1691624

End: 1693003

Strand: Reverse

Name: glmM

Synonym: BH14740

Alternate gene names: 49476133

Gene position: 1693003-1691624 (Counterclockwise)

Preceding gene: 49476134

Following gene: 49476130

Centisome position: 87.67

GC content: 42.83

Gene sequence:

>1380_bases
ATGCCACAAAAATATTTTGGTACAGATGGAATTCGCGGCAAAGCCAATGTTTTTCCCATGACACCAGATTTTGCTATGAA
AGTGGGGATGGCTGTGGGAATTTTGTTTCGGTCACAAAATCAGTCGCGTCGTGTGGTAATTGGTAAAGATACCCGTTTGT
CTGGTTATATGCTCGAAAATGCTTTGGTTTCAGGATTTACCGCTGCTGGAATGGAGGCGTTCTTATTAGGACCGGTGCCA
ACACCTGCTGTTGCTATGCTTTGTCGCTCATTGCGTGCTGATCTGGGGGTGATGATTTCGGCCTCTCATAATCCCTTCTA
TGATAATGGTATTAAACTTTTTGGTCCTGATGGCTTTAAGCTTTCAGATGAGATAGAAGAAAAAATTGAACAATTGATCG
ATACAGATCTTTCAAAATCTTTAGCCAGTTGTGCCGAAATTGGCTATGCAAAACGGGTCGAGGGTGATATTTACCGCTAT
ATCGAATATGCCAAAAGAACTTTGCCGCGCGATGTTCGTTTGGATAATTTGCGTATCGTTGTCGATTGCGCTAATGGTGC
TGCTTATAAGGCGGCTCCGCGTGCTTTATGGGAATTGGGAGCTGAGGTCTTTGCGATTAATGATACACCAAATGGTACCA
ATATTAATCACAAATGCGGTTCAACCGATTTGGCCTCTTTAAAACAAAAAGTTCATGAAGTGCGCGCTGATGTGGGTATT
GCTCTCGATGGGGATGGAGATCGTGTTCTTCTTGTGGATGAAAAAGCTCAAACCGTTGATGGGGATCAGTTGATCGCTGT
TATTGCTGAACATTGGCATAAAAACGGACGTTTGCAGTCTAAGGGTGTTGTTACAACTATTATGTCAAATCTTGGACTCG
AGCGCTTCTTAAACAGCAAAGGGTTAGATCTTGTTCGGACAAAGGTAGGGGATCGCTATGTGGTCGATGCGATGCGCAAG
AAGGGATATAATGTTGGGGGTGAAGCTTCTGGGCATATTGTGCTGAGTGATTTTGGTACAACGGGTGATGGTTTAGTAGC
TGCTTTGCAGATTTTAGCTTGTATGCAAGAAATCCAAATTCCTATGAGTCACTTGTGTCAGCGCTTTGAACCTGTGCCAC
AAATTTTCAAAAACGTAATGATTAAAAACAAAAATGTGCTGAAAAAAAATCCGGTCAAAACAGCAATAGAGCAAGCAACA
CAGCGTTTAGGAAAAAAAGCAAGACTGGTGATTCGTGCTTCTGGAACCGAGCCCGTAATTCGTATTATGGGGGAAGGCGA
TGAGAGAGAAATGCTTGATGCTGTTGTGACAGAGATGGTAGATATTATTACACATCATGATACCCTTTCAAAAGCGTGTG
CTTCTCTGGAAAGATCGTGA

Upstream 100 bases:

>100_bases
AAAATGGTAAGACTCTAATGATCTCTTGGGAGATTTTGCACTACTAGAGCGCTGTTTGGTTAAGACTGCAAGAAAAGAAA
TGCATATAAAGGAAAGAGGA

Downstream 100 bases:

>100_bases
AGATTTTGAGAGAATTGATCGAATAATTACGTAACATTCTTAGGAAAGAGCTTCGACAGGTAATCTGTGCTTCTGAAACC
GATCTTGGCTCGAGCGCTTC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MPQKYFGTDGIRGKANVFPMTPDFAMKVGMAVGILFRSQNQSRRVVIGKDTRLSGYMLENALVSGFTAAGMEAFLLGPVP
TPAVAMLCRSLRADLGVMISASHNPFYDNGIKLFGPDGFKLSDEIEEKIEQLIDTDLSKSLASCAEIGYAKRVEGDIYRY
IEYAKRTLPRDVRLDNLRIVVDCANGAAYKAAPRALWELGAEVFAINDTPNGTNINHKCGSTDLASLKQKVHEVRADVGI
ALDGDGDRVLLVDEKAQTVDGDQLIAVIAEHWHKNGRLQSKGVVTTIMSNLGLERFLNSKGLDLVRTKVGDRYVVDAMRK
KGYNVGGEASGHIVLSDFGTTGDGLVAALQILACMQEIQIPMSHLCQRFEPVPQIFKNVMIKNKNVLKKNPVKTAIEQAT
QRLGKKARLVIRASGTEPVIRIMGEGDEREMLDAVVTEMVDIITHHDTLSKACASLERS

Sequences:

>Translated_459_residues
MPQKYFGTDGIRGKANVFPMTPDFAMKVGMAVGILFRSQNQSRRVVIGKDTRLSGYMLENALVSGFTAAGMEAFLLGPVP
TPAVAMLCRSLRADLGVMISASHNPFYDNGIKLFGPDGFKLSDEIEEKIEQLIDTDLSKSLASCAEIGYAKRVEGDIYRY
IEYAKRTLPRDVRLDNLRIVVDCANGAAYKAAPRALWELGAEVFAINDTPNGTNINHKCGSTDLASLKQKVHEVRADVGI
ALDGDGDRVLLVDEKAQTVDGDQLIAVIAEHWHKNGRLQSKGVVTTIMSNLGLERFLNSKGLDLVRTKVGDRYVVDAMRK
KGYNVGGEASGHIVLSDFGTTGDGLVAALQILACMQEIQIPMSHLCQRFEPVPQIFKNVMIKNKNVLKKNPVKTAIEQAT
QRLGKKARLVIRASGTEPVIRIMGEGDEREMLDAVVTEMVDIITHHDTLSKACASLERS
>Mature_458_residues
PQKYFGTDGIRGKANVFPMTPDFAMKVGMAVGILFRSQNQSRRVVIGKDTRLSGYMLENALVSGFTAAGMEAFLLGPVPT
PAVAMLCRSLRADLGVMISASHNPFYDNGIKLFGPDGFKLSDEIEEKIEQLIDTDLSKSLASCAEIGYAKRVEGDIYRYI
EYAKRTLPRDVRLDNLRIVVDCANGAAYKAAPRALWELGAEVFAINDTPNGTNINHKCGSTDLASLKQKVHEVRADVGIA
LDGDGDRVLLVDEKAQTVDGDQLIAVIAEHWHKNGRLQSKGVVTTIMSNLGLERFLNSKGLDLVRTKVGDRYVVDAMRKK
GYNVGGEASGHIVLSDFGTTGDGLVAALQILACMQEIQIPMSHLCQRFEPVPQIFKNVMIKNKNVLKKNPVKTAIEQATQ
RLGKKARLVIRASGTEPVIRIMGEGDEREMLDAVVTEMVDIITHHDTLSKACASLERS

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=439, Percent_Identity=48.9749430523918, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1788361, Length=449, Percent_Identity=25.6124721603563, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_BARHE (Q6G5P7)

Other databases:

- EMBL:   BX897699
- RefSeq:   YP_034174.1
- ProteinModelPortal:   Q6G5P7
- GeneID:   2866034
- GenomeReviews:   BX897699_GR
- KEGG:   bhe:BH14740
- NMPDR:   fig|283166.1.peg.1302
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- PhylomeDB:   Q6G5P7
- ProtClustDB:   PRK10887
- BioCyc:   BHEN283166:BH14740-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 50234; Mature: 50102

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQKYFGTDGIRGKANVFPMTPDFAMKVGMAVGILFRSQNQSRRVVIGKDTRLSGYMLEN
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCHHHHHH
ALVSGFTAAGMEAFLLGPVPTPAVAMLCRSLRADLGVMISASHNPFYDNGIKLFGPDGFK
HHHHCHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCC
LSDEIEEKIEQLIDTDLSKSLASCAEIGYAKRVEGDIYRYIEYAKRTLPRDVRLDNLRIV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCEECCEEEE
VDCANGAAYKAAPRALWELGAEVFAINDTPNGTNINHKCGSTDLASLKQKVHEVRADVGI
EEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCE
ALDGDGDRVLLVDEKAQTVDGDQLIAVIAEHWHKNGRLQSKGVVTTIMSNLGLERFLNSK
EEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHCCC
GLDLVRTKVGDRYVVDAMRKKGYNVGGEASGHIVLSDFGTTGDGLVAALQILACMQEIQI
CCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC
PMSHLCQRFEPVPQIFKNVMIKNKNVLKKNPVKTAIEQATQRLGKKARLVIRASGTEPVI
CHHHHHHHCCHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEE
RIMGEGDEREMLDAVVTEMVDIITHHDTLSKACASLERS
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PQKYFGTDGIRGKANVFPMTPDFAMKVGMAVGILFRSQNQSRRVVIGKDTRLSGYMLEN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCHHHHHH
ALVSGFTAAGMEAFLLGPVPTPAVAMLCRSLRADLGVMISASHNPFYDNGIKLFGPDGFK
HHHHCHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCC
LSDEIEEKIEQLIDTDLSKSLASCAEIGYAKRVEGDIYRYIEYAKRTLPRDVRLDNLRIV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCEECCEEEE
VDCANGAAYKAAPRALWELGAEVFAINDTPNGTNINHKCGSTDLASLKQKVHEVRADVGI
EEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCE
ALDGDGDRVLLVDEKAQTVDGDQLIAVIAEHWHKNGRLQSKGVVTTIMSNLGLERFLNSK
EEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHCCC
GLDLVRTKVGDRYVVDAMRKKGYNVGGEASGHIVLSDFGTTGDGLVAALQILACMQEIQI
CCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC
PMSHLCQRFEPVPQIFKNVMIKNKNVLKKNPVKTAIEQATQRLGKKARLVIRASGTEPVI
CHHHHHHHCCHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEE
RIMGEGDEREMLDAVVTEMVDIITHHDTLSKACASLERS
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA