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The map label for this gene is sigH [H]

Identifier: 49476049

GI number: 49476049

Start: 1590131

End: 1590685

Strand: Reverse

Name: sigH [H]

Synonym: BH13830

Alternate gene names: 49476049

Gene position: 1590685-1590131 (Counterclockwise)

Preceding gene: 49476050

Following gene: 49476048

Centisome position: 82.37

GC content: 41.44

Gene sequence:

>555_bases
ATGGCAAAAAGCATGAAAGATTTTAAACAGGAACTCCTTCTGATCCTACCGTCTCTGCGGGCTTTTGCACTTTCTTTAAG
CAGCAAGCATGATAAAGCAGAGGATTTGGTTCAAGATACTCTTATGAAAGCATGGGCTAAGCAGGACAGTTTTGAAATGG
GAACCAATCTTAAAGCTTGGCTTTTTACCATTTTACGCAATGAATTTTACAGTCAAATGCGCAAAAGGGGCAGAGAAGTT
CAAGACAGCGAAGGGGTCTTTAGTGAAAATGTGGCTGTTCATCCTCCTCAATATGGGTCGCTTGATTTGCAAGATTTTAA
AAAAGCCTTAAATCTACTTTCTGCTGATCAAAGAGAAGCCATTATTCTGATTGGTGCATCCGGTTTTTCTTATGAAGATG
CTGCAGCGATTTGTGGTTGTGCTGTTGGAACAATTAAAAGCCGTGTAAGCCGAGCGCGTAATCGTTTACAGGAACTCCTC
AAAGTGGATGGTGAATCCGATTATGGTCCCGATTCTTATTCGGCTGGGAGCACATTATGTTCATTTAACGGCTAA

Upstream 100 bases:

>100_bases
CAGGAAGAAGCACTGCCTGCTCATTTACTTGAACTTTTGGATAGGTTGGAGAAAGCAGAGCAATTTGGCTTAAAAAATGT
GGAAAAGGTTTGAATCCTTT

Downstream 100 bases:

>100_bases
AAAAGTACAATAATTATGTTTAAGAGCCTTGTTTTTTTAATTCCCTTTATAGCTATTAAAGTAAAGTCAGCATCTAAAGA
AATTCATGGTGTTTAGCGTG

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MAKSMKDFKQELLLILPSLRAFALSLSSKHDKAEDLVQDTLMKAWAKQDSFEMGTNLKAWLFTILRNEFYSQMRKRGREV
QDSEGVFSENVAVHPPQYGSLDLQDFKKALNLLSADQREAIILIGASGFSYEDAAAICGCAVGTIKSRVSRARNRLQELL
KVDGESDYGPDSYSAGSTLCSFNG

Sequences:

>Translated_184_residues
MAKSMKDFKQELLLILPSLRAFALSLSSKHDKAEDLVQDTLMKAWAKQDSFEMGTNLKAWLFTILRNEFYSQMRKRGREV
QDSEGVFSENVAVHPPQYGSLDLQDFKKALNLLSADQREAIILIGASGFSYEDAAAICGCAVGTIKSRVSRARNRLQELL
KVDGESDYGPDSYSAGSTLCSFNG
>Mature_183_residues
AKSMKDFKQELLLILPSLRAFALSLSSKHDKAEDLVQDTLMKAWAKQDSFEMGTNLKAWLFTILRNEFYSQMRKRGREVQ
DSEGVFSENVAVHPPQYGSLDLQDFKKALNLLSADQREAIILIGASGFSYEDAAAICGCAVGTIKSRVSRARNRLQELLK
VDGESDYGPDSYSAGSTLCSFNG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014293
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20427; Mature: 20296

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSMKDFKQELLLILPSLRAFALSLSSKHDKAEDLVQDTLMKAWAKQDSFEMGTNLKAW
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHCCCCHHHH
LFTILRNEFYSQMRKRGREVQDSEGVFSENVAVHPPQYGSLDLQDFKKALNLLSADQREA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCE
IILIGASGFSYEDAAAICGCAVGTIKSRVSRARNRLQELLKVDGESDYGPDSYSAGSTLC
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SFNG
CCCC
>Mature Secondary Structure 
AKSMKDFKQELLLILPSLRAFALSLSSKHDKAEDLVQDTLMKAWAKQDSFEMGTNLKAW
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHCCCCHHHH
LFTILRNEFYSQMRKRGREVQDSEGVFSENVAVHPPQYGSLDLQDFKKALNLLSADQREA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCE
IILIGASGFSYEDAAAICGCAVGTIKSRVSRARNRLQELLKVDGESDYGPDSYSAGSTLC
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SFNG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]