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The map label for this gene is ftsA [H]

Identifier: 49475850

GI number: 49475850

Start: 1233909

End: 1235207

Strand: Reverse

Name: ftsA [H]

Synonym: BH11190

Alternate gene names: 49475850

Gene position: 1235207-1233909 (Counterclockwise)

Preceding gene: 49475851

Following gene: 49475849

Centisome position: 63.97

GC content: 43.49

Gene sequence:

>1299_bases
ATGTTACTCAAATCACATCATAGCGGGGGACGCAAAACTCGTTTTTTGACGGTTCTTGATGTCGGATCAAGTAAAATTGT
GTGTCTTATTGCTTGTTTGCGTCCTTTGAAGCATGCACATTATTTACATGGTCGTACACATTCTATGGAAATTTTAGGAT
TTGGAGTGCAGCGTTCACGCGGTATCAAATCCGGTGTTGTGATGGATATATTTGCAGCAGAGCAATCGATACGTTTGGCT
GTTGATGCGGCAGAAAAAATGGCTGGTTTGGTGGTGGATTCGGTAATTGTGAACTTTTCCTCAAGCCGATTACAAAGTGC
TCTTATCAATGGCGTGGTAAGTTTGAATGGTCGTGAAGTCACCAAGCGTGATATACGTGTGGCATTTGCAGATGTTTCAC
GCAAAGCTTTTAATGCTGAGCGCCATGTCGTACATTCAGTTCCGGTTTCTTATGTCTTAGATGGAGATAAAGGAATTTCT
GATCCTGTTGGAATGATCGGAGATTTTTTTGGAGTAGATGTGCATGTGGTAACAGCGGAAACAGCGGCTTTGCGTAATTT
AGAAACTTGCATTAATCGTGCGCATTTGAGTGTCGAAGCGATGGTTGTAACTCCCTTTGCCAGTGGTCTTGCTGTTTTGA
TGAATGATGAGGCGCATTTAGGAGCGGCATGTATTGACTTTGGCGGTGGAACAACAACATTTTCAGTGTTTTCTGAAGGA
AAATTTGTCCATGCCAATGCACTTGCCGTTGGGGGACATCATGTGACTCTTGATGTTGCGCGTGGATTCTCTATGTCACT
TCCAGAGGCAGAACGTTTAAAGGTTGTCTATGGTTCTGCGCTTGTTACAAGTGCTGATGAACGCCATATGGTTAATGTGA
CAGAGATTGGCAATGAGCACCGTGAAATCCAATATCCACGTGCTGTTCTTGGGCGTATCATTCGTGCGCGTGTTGAAGAA
ATTTTAGAGATGGTGCGTGATTGTTTAAATCGCTCTGGTTTTGGTCATATCATTGGTAAGCGTGTTATTTTGACTGGGGG
AGCAAGCCAGTTAACAGGGTTGCCAGAAATGGCACGTACTATATTGGGAAGAAATGTTCGTATAGGACGGCCTTTAGGTA
TTTCGAGGCTTCCTTCTCTTGCAAAAGGGGCGGCGTTTACATCTGCTGTTGGATTGTTAATTTATCCGCAATTGGTGGGG
TTTGAAGAAAAAACAATGCAAGTTGCAGTAAATCATTTATCGACCGGCACACGTGGATATTTTCAGCGTGTTGGTCAGTG
GTTGCGTGAGAGTTTTTAA

Upstream 100 bases:

>100_bases
GTATTACAGTGGCTTTATCTGATGAGGTGTTAGAACGTCATCGTGCTTTTGTAGCAGAAGAACAACGCGTTTTGAAGGCG
CGAAAGGCAGGAAAACTATG

Downstream 100 bases:

>100_bases
GTAAGTCTATTGAGATAAAGTTAAATTTCATCGCTTTGACTTGCGATGTCTTATGAGAAGGAAAAGGAAATGACGATTAA
TCTGCATCGGCCAGATATCG

Product: cell division protein ftsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MLLKSHHSGGRKTRFLTVLDVGSSKIVCLIACLRPLKHAHYLHGRTHSMEILGFGVQRSRGIKSGVVMDIFAAEQSIRLA
VDAAEKMAGLVVDSVIVNFSSSRLQSALINGVVSLNGREVTKRDIRVAFADVSRKAFNAERHVVHSVPVSYVLDGDKGIS
DPVGMIGDFFGVDVHVVTAETAALRNLETCINRAHLSVEAMVVTPFASGLAVLMNDEAHLGAACIDFGGGTTTFSVFSEG
KFVHANALAVGGHHVTLDVARGFSMSLPEAERLKVVYGSALVTSADERHMVNVTEIGNEHREIQYPRAVLGRIIRARVEE
ILEMVRDCLNRSGFGHIIGKRVILTGGASQLTGLPEMARTILGRNVRIGRPLGISRLPSLAKGAAFTSAVGLLIYPQLVG
FEEKTMQVAVNHLSTGTRGYFQRVGQWLRESF

Sequences:

>Translated_432_residues
MLLKSHHSGGRKTRFLTVLDVGSSKIVCLIACLRPLKHAHYLHGRTHSMEILGFGVQRSRGIKSGVVMDIFAAEQSIRLA
VDAAEKMAGLVVDSVIVNFSSSRLQSALINGVVSLNGREVTKRDIRVAFADVSRKAFNAERHVVHSVPVSYVLDGDKGIS
DPVGMIGDFFGVDVHVVTAETAALRNLETCINRAHLSVEAMVVTPFASGLAVLMNDEAHLGAACIDFGGGTTTFSVFSEG
KFVHANALAVGGHHVTLDVARGFSMSLPEAERLKVVYGSALVTSADERHMVNVTEIGNEHREIQYPRAVLGRIIRARVEE
ILEMVRDCLNRSGFGHIIGKRVILTGGASQLTGLPEMARTILGRNVRIGRPLGISRLPSLAKGAAFTSAVGLLIYPQLVG
FEEKTMQVAVNHLSTGTRGYFQRVGQWLRESF
>Mature_432_residues
MLLKSHHSGGRKTRFLTVLDVGSSKIVCLIACLRPLKHAHYLHGRTHSMEILGFGVQRSRGIKSGVVMDIFAAEQSIRLA
VDAAEKMAGLVVDSVIVNFSSSRLQSALINGVVSLNGREVTKRDIRVAFADVSRKAFNAERHVVHSVPVSYVLDGDKGIS
DPVGMIGDFFGVDVHVVTAETAALRNLETCINRAHLSVEAMVVTPFASGLAVLMNDEAHLGAACIDFGGGTTTFSVFSEG
KFVHANALAVGGHHVTLDVARGFSMSLPEAERLKVVYGSALVTSADERHMVNVTEIGNEHREIQYPRAVLGRIIRARVEE
ILEMVRDCLNRSGFGHIIGKRVILTGGASQLTGLPEMARTILGRNVRIGRPLGISRLPSLAKGAAFTSAVGLLIYPQLVG
FEEKTMQVAVNHLSTGTRGYFQRVGQWLRESF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=430, Percent_Identity=29.5348837209302, Blast_Score=186, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 46710; Mature: 46710

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKSHHSGGRKTRFLTVLDVGSSKIVCLIACLRPLKHAHYLHGRTHSMEILGFGVQRSR
CCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHCC
GIKSGVVMDIFAAEQSIRLAVDAAEKMAGLVVDSVIVNFSSSRLQSALINGVVSLNGREV
CCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCEE
TKRDIRVAFADVSRKAFNAERHVVHSVPVSYVLDGDKGISDPVGMIGDFFGVDVHVVTAE
CHHHHEEHHHHHHHHHHCCHHHHHEECCEEEEEECCCCCCCCHHHHHHHHCCEEEEEECC
TAALRNLETCINRAHLSVEAMVVTPFASGLAVLMNDEAHLGAACIDFGGGTTTFSVFSEG
HHHHHHHHHHHHHHHCEEEEEEEECCCCCEEEEECCCCCCCEEEEECCCCCEEEEEECCC
KFVHANALAVGGHHVTLDVARGFSMSLPEAERLKVVYGSALVTSADERHMVNVTEIGNEH
CEEEEEEEEECCEEEEEEEECCCCCCCCCHHHEEEEECCEEEECCCCCEEEEHHHCCCCH
REIQYPRAVLGRIIRARVEEILEMVRDCLNRSGFGHIIGKRVILTGGASQLTGLPEMART
HHEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHCCCHHHHHH
ILGRNVRIGRPLGISRLPSLAKGAAFTSAVGLLIYPQLVGFEEKTMQVAVNHLSTGTRGY
HHCCCCEECCCCCHHHCCHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
FQRVGQWLRESF
HHHHHHHHHHCC
>Mature Secondary Structure
MLLKSHHSGGRKTRFLTVLDVGSSKIVCLIACLRPLKHAHYLHGRTHSMEILGFGVQRSR
CCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHCC
GIKSGVVMDIFAAEQSIRLAVDAAEKMAGLVVDSVIVNFSSSRLQSALINGVVSLNGREV
CCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCEE
TKRDIRVAFADVSRKAFNAERHVVHSVPVSYVLDGDKGISDPVGMIGDFFGVDVHVVTAE
CHHHHEEHHHHHHHHHHCCHHHHHEECCEEEEEECCCCCCCCHHHHHHHHCCEEEEEECC
TAALRNLETCINRAHLSVEAMVVTPFASGLAVLMNDEAHLGAACIDFGGGTTTFSVFSEG
HHHHHHHHHHHHHHHCEEEEEEEECCCCCEEEEECCCCCCCEEEEECCCCCEEEEEECCC
KFVHANALAVGGHHVTLDVARGFSMSLPEAERLKVVYGSALVTSADERHMVNVTEIGNEH
CEEEEEEEEECCEEEEEEEECCCCCCCCCHHHEEEEECCEEEECCCCCEEEEHHHCCCCH
REIQYPRAVLGRIIRARVEEILEMVRDCLNRSGFGHIIGKRVILTGGASQLTGLPEMART
HHEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHCCCHHHHHH
ILGRNVRIGRPLGISRLPSLAKGAAFTSAVGLLIYPQLVGFEEKTMQVAVNHLSTGTRGY
HHCCCCEECCCCCHHHCCHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
FQRVGQWLRESF
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352931; 11481430 [H]