| Definition | Bartonella henselae str. Houston-1, complete genome. |
|---|---|
| Accession | NC_005956 |
| Length | 1,931,047 |
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The map label for this gene is kefA [H]
Identifier: 49475816
GI number: 49475816
Start: 1181984
End: 1184347
Strand: Reverse
Name: kefA [H]
Synonym: BH10810
Alternate gene names: 49475816
Gene position: 1184347-1181984 (Counterclockwise)
Preceding gene: 49475821
Following gene: 49475815
Centisome position: 61.33
GC content: 34.94
Gene sequence:
>2364_bases ATGTGTTCATTTTTTAAAAAAAAATTATGCATTTTTTTCTTCATTCTTGGGAATGTTGTTGGATGGAGCTCTTGTGTATG GGGGCATCTAGGATCACAATATACAATAATTGGGCAATCGGTAATTTCTCACTCAATTGATGAAATTATTCAAAAACAAC AACAAATTATTAAGATACTTGAACAAGAGATAAAAAATTTACAAAAAGATTTTGCCAACGAATCAGCAAATGAATATGCT TTAGCAAAGGTGCGCTTGCGCGCGCGAGATATCAATAAACGTGCTATAGAAGCAGCATTTGTTTTGCGTAATCCTCTTAA TGATATTAACGTTCTTCTTGATCAATTGAAAGAGCTCCAAGATGAGCCAAAAAATTTGAAAGAGCGCTCTCATCTGATAA AGAAAAAAGCACAGATTAATAATATGGTGCTGCAGTTCGAAGAAATCTTTTTGGCTACAAATAAAATAGTTGAACTTTCT CTTTCTCAGTCTCGAGAACTTTTTAAACGCACATTTAAGAACAGACTTGAGTTTTCAATACCGATGCTTAAATATTCCGT TGAGAAAATGAAAGAGGCTTCCTCTGATTTTCTTTTTCTATTTAGTTCTTGGTGTAAATTCGTATTTCATTTCAAATTTT TACAGCTGTTTCTTTCCTTTTTAGTTCCGCTTTTTGTTGCTTTGGGTCTTTCTTATTTTTCTCGTAAAGTTCTCGCACAT GTGAACTGCTATTTTACTAAGGGCAATGAGGAAATATCTTATTTACAACGCTTATTGGTTGCTTTTATTTCAATTCTTTT GCCTTTGCTTGTTTGTGTTGTTTGCGTTTATCTCGTGTTTTTTTTGTTTCATAGTTTTGGTATGGAGTTAGGGAAGCTCA CAACGATATTTTATACCGTTGGACATCAAATTATTTTAGTCTTTTTGATCAACCGTTTAGCTCTTGTTCTTTTATCATTG AATATGGTTCATGTGCGCCTTTTTAATATTACGCCGTTTGTGGCACATCAATTGGTAATTTTGCTCACTTTTCTAGGTGG CATTTTGGCATTTGATGCTGTTCTTGATAGTATTTATCAAGTCGTTTCAGCTTCTCTTTCTTTGACAATTGCCAAAAGTT TTATTGCTGTTTTTCTTTTTGCAATACTGCTGTTTATAATTTCATTTGTGCCGTTGCGGTTTAGACGTAAATCTTCTCAA AATGAAGAGAGAGAAACGCATTTTTTGCCACTTTATATACGTATTCCATTCATTGTATTGGGATTATTGCTTATTGTGAT GGATTCTTTAGGGTATGTTGGTTTGGCGCATTTTATTATGCAGCAAATCGTGATTGGTGGTGCATTTTTGGTTCTCATGT ATTTAGGAATAAAAAGCGCTCAAGTAATTGGAACTAAAGGGCAATTTATGAAAACGAGCGTTGGTCATGCTTTGATGCAA TGGTTCCATTTAGAAGAGAAAACAATGAATAAGTTGGGGATTGTGATAAGTGTTGTTCTCAATTTAATTGTGGTTATACT TTGTGCAATGCCAATTGCTGTGCAATTTGGATTTTCGTATTCTGATTTGCGAAGGGTATTATTGCAGGTTATGACCGGTT TTCAAATTGGAAATATATCTGTTTCTTTAATTTCTATTGTAATTGGAATCATTGCTTTCTTTGCTTGTTGGTTCCTTAAC CGCCGATTTATCTGCTGGCTGGATGGAATGGTATTGGTGCATGGGGAGTTTGATTCTGGTGTCCGTAATTCTATTAAAAC AGTCATTAGTTATGCTGGTGTTGTTGTTTCTGCTTTGATAGGATTGTCAATGGCAGGTTTGGATCTCAAAAATTTTGCAC TCATTGCTGGTGGGCTTTCACTTGGTATAGGTTTTGGTTTACAAAATATTGTTCAAAATTTTGTCTCTGGACTTATCATT TTGATTGGAAGACCATTTAAACTTGGAGATTATGTGGAAGCTGGATCAGTGGGGGGGATTGTCAAACGTATTAGTGTACG TGCGACAGAACTTGAAACATTTCAGCGAAAGACAATCATTATTCCTAATTCAAGTCTCATTAATAATAACGTTAGTAATT GGACTAGAGGGAGCAAAATGGGGCGGGTTGATATCCCTATTGTTGTTTCTCCTAATGTTGCTCCAGAGCGTGTTGTTGAA ATTTTGCTAGAGATTGCTTCTACGACAGAAGGTGTTTTAAAAAACCCTGCGCCGCAGGTGAGTTTTACTGCGTTCGATAG TAAGAAATTTTCATTTAGTTTGGCTGTTTATGTGCCTAACATTACCTCATCTTTTAAGGTAACAAATGCTCTTCATTTTG TATTATATAAACGTTTTGTTCAGGAAGGAATCCTAGAGTGCTGA
Upstream 100 bases:
>100_bases GGGAAGCTTGTATAAAAATTATTCTACATAAGTTGAAAATATTTGTCTCATTTCATATTTCTACGAAGAGGGGATTCCAC ATCTTAGACCTAAGGTAGAT
Downstream 100 bases:
>100_bases AATATCTTCATGTTTTTGTTGCGGTCACCTTGTTGGATATTTTTATCATGACAACTTTTGCAGCAACTGTGAAAAATACT GATTTAAAGATACAATCTTT
Product: hypothetical protein
Products: NA
Alternate protein names: Protein AefA [H]
Number of amino acids: Translated: 787; Mature: 787
Protein sequence:
>787_residues MCSFFKKKLCIFFFILGNVVGWSSCVWGHLGSQYTIIGQSVISHSIDEIIQKQQQIIKILEQEIKNLQKDFANESANEYA LAKVRLRARDINKRAIEAAFVLRNPLNDINVLLDQLKELQDEPKNLKERSHLIKKKAQINNMVLQFEEIFLATNKIVELS LSQSRELFKRTFKNRLEFSIPMLKYSVEKMKEASSDFLFLFSSWCKFVFHFKFLQLFLSFLVPLFVALGLSYFSRKVLAH VNCYFTKGNEEISYLQRLLVAFISILLPLLVCVVCVYLVFFLFHSFGMELGKLTTIFYTVGHQIILVFLINRLALVLLSL NMVHVRLFNITPFVAHQLVILLTFLGGILAFDAVLDSIYQVVSASLSLTIAKSFIAVFLFAILLFIISFVPLRFRRKSSQ NEERETHFLPLYIRIPFIVLGLLLIVMDSLGYVGLAHFIMQQIVIGGAFLVLMYLGIKSAQVIGTKGQFMKTSVGHALMQ WFHLEEKTMNKLGIVISVVLNLIVVILCAMPIAVQFGFSYSDLRRVLLQVMTGFQIGNISVSLISIVIGIIAFFACWFLN RRFICWLDGMVLVHGEFDSGVRNSIKTVISYAGVVVSALIGLSMAGLDLKNFALIAGGLSLGIGFGLQNIVQNFVSGLII LIGRPFKLGDYVEAGSVGGIVKRISVRATELETFQRKTIIIPNSSLINNNVSNWTRGSKMGRVDIPIVVSPNVAPERVVE ILLEIASTTEGVLKNPAPQVSFTAFDSKKFSFSLAVYVPNITSSFKVTNALHFVLYKRFVQEGILEC
Sequences:
>Translated_787_residues MCSFFKKKLCIFFFILGNVVGWSSCVWGHLGSQYTIIGQSVISHSIDEIIQKQQQIIKILEQEIKNLQKDFANESANEYA LAKVRLRARDINKRAIEAAFVLRNPLNDINVLLDQLKELQDEPKNLKERSHLIKKKAQINNMVLQFEEIFLATNKIVELS LSQSRELFKRTFKNRLEFSIPMLKYSVEKMKEASSDFLFLFSSWCKFVFHFKFLQLFLSFLVPLFVALGLSYFSRKVLAH VNCYFTKGNEEISYLQRLLVAFISILLPLLVCVVCVYLVFFLFHSFGMELGKLTTIFYTVGHQIILVFLINRLALVLLSL NMVHVRLFNITPFVAHQLVILLTFLGGILAFDAVLDSIYQVVSASLSLTIAKSFIAVFLFAILLFIISFVPLRFRRKSSQ NEERETHFLPLYIRIPFIVLGLLLIVMDSLGYVGLAHFIMQQIVIGGAFLVLMYLGIKSAQVIGTKGQFMKTSVGHALMQ WFHLEEKTMNKLGIVISVVLNLIVVILCAMPIAVQFGFSYSDLRRVLLQVMTGFQIGNISVSLISIVIGIIAFFACWFLN RRFICWLDGMVLVHGEFDSGVRNSIKTVISYAGVVVSALIGLSMAGLDLKNFALIAGGLSLGIGFGLQNIVQNFVSGLII LIGRPFKLGDYVEAGSVGGIVKRISVRATELETFQRKTIIIPNSSLINNNVSNWTRGSKMGRVDIPIVVSPNVAPERVVE ILLEIASTTEGVLKNPAPQVSFTAFDSKKFSFSLAVYVPNITSSFKVTNALHFVLYKRFVQEGILEC >Mature_787_residues MCSFFKKKLCIFFFILGNVVGWSSCVWGHLGSQYTIIGQSVISHSIDEIIQKQQQIIKILEQEIKNLQKDFANESANEYA LAKVRLRARDINKRAIEAAFVLRNPLNDINVLLDQLKELQDEPKNLKERSHLIKKKAQINNMVLQFEEIFLATNKIVELS LSQSRELFKRTFKNRLEFSIPMLKYSVEKMKEASSDFLFLFSSWCKFVFHFKFLQLFLSFLVPLFVALGLSYFSRKVLAH VNCYFTKGNEEISYLQRLLVAFISILLPLLVCVVCVYLVFFLFHSFGMELGKLTTIFYTVGHQIILVFLINRLALVLLSL NMVHVRLFNITPFVAHQLVILLTFLGGILAFDAVLDSIYQVVSASLSLTIAKSFIAVFLFAILLFIISFVPLRFRRKSSQ NEERETHFLPLYIRIPFIVLGLLLIVMDSLGYVGLAHFIMQQIVIGGAFLVLMYLGIKSAQVIGTKGQFMKTSVGHALMQ WFHLEEKTMNKLGIVISVVLNLIVVILCAMPIAVQFGFSYSDLRRVLLQVMTGFQIGNISVSLISIVIGIIAFFACWFLN RRFICWLDGMVLVHGEFDSGVRNSIKTVISYAGVVVSALIGLSMAGLDLKNFALIAGGLSLGIGFGLQNIVQNFVSGLII LIGRPFKLGDYVEAGSVGGIVKRISVRATELETFQRKTIIIPNSSLINNNVSNWTRGSKMGRVDIPIVVSPNVAPERVVE ILLEIASTTEGVLKNPAPQVSFTAFDSKKFSFSLAVYVPNITSSFKVTNALHFVLYKRFVQEGILEC
Specific function: Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell, although it does not appear to have a major role in osmolarity regulation. Form
COG id: COG3264
COG function: function code M; Small-conductance mechanosensitive channel
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the mscS (TC 1.A.23) family [H]
Homologues:
Organism=Escherichia coli, GI1786670, Length=258, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=1e-33, Organism=Escherichia coli, GI2367355, Length=244, Percent_Identity=31.1475409836066, Blast_Score=130, Evalue=3e-31, Organism=Escherichia coli, GI1789291, Length=221, Percent_Identity=24.8868778280543, Blast_Score=75, Evalue=2e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR010920 - InterPro: IPR011066 - InterPro: IPR006685 - InterPro: IPR006686 - InterPro: IPR011014 [H]
Pfam domain/function: PF00924 MS_channel [H]
EC number: NA
Molecular weight: Translated: 88596; Mature: 88596
Theoretical pI: Translated: 9.94; Mature: 9.94
Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01246 UPF0003
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MCSFFKKKLCIFFFILGNVVGWSSCVWGHLGSQYTIIGQSVISHSIDEIIQKQQQIIKIL CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH EQEIKNLQKDFANESANEYALAKVRLRARDINKRAIEAAFVLRNPLNDINVLLDQLKELQ HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH DEPKNLKERSHLIKKKAQINNMVLQFEEIFLATNKIVELSLSQSRELFKRTFKNRLEFSI CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PMLKYSVEKMKEASSDFLFLFSSWCKFVFHFKFLQLFLSFLVPLFVALGLSYFSRKVLAH HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VNCYFTKGNEEISYLQRLLVAFISILLPLLVCVVCVYLVFFLFHSFGMELGKLTTIFYTV HEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH GHQIILVFLINRLALVLLSLNMVHVRLFNITPFVAHQLVILLTFLGGILAFDAVLDSIYQ HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VVSASLSLTIAKSFIAVFLFAILLFIISFVPLRFRRKSSQNEERETHFLPLYIRIPFIVL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCEEEHHHHHHHHHH GLLLIVMDSLGYVGLAHFIMQQIVIGGAFLVLMYLGIKSAQVIGTKGQFMKTSVGHALMQ HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHH WFHLEEKTMNKLGIVISVVLNLIVVILCAMPIAVQFGFSYSDLRRVLLQVMTGFQIGNIS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHH VSLISIVIGIIAFFACWFLNRRFICWLDGMVLVHGEFDSGVRNSIKTVISYAGVVVSALI HHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH GLSMAGLDLKNFALIAGGLSLGIGFGLQNIVQNFVSGLIILIGRPFKLGDYVEAGSVGGI HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH VKRISVRATELETFQRKTIIIPNSSLINNNVSNWTRGSKMGRVDIPIVVSPNVAPERVVE HHHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHH ILLEIASTTEGVLKNPAPQVSFTAFDSKKFSFSLAVYVPNITSSFKVTNALHFVLYKRFV HHHHHHHCCHHHHCCCCCCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHH QEGILEC HHHCCCC >Mature Secondary Structure MCSFFKKKLCIFFFILGNVVGWSSCVWGHLGSQYTIIGQSVISHSIDEIIQKQQQIIKIL CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH EQEIKNLQKDFANESANEYALAKVRLRARDINKRAIEAAFVLRNPLNDINVLLDQLKELQ HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH DEPKNLKERSHLIKKKAQINNMVLQFEEIFLATNKIVELSLSQSRELFKRTFKNRLEFSI CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PMLKYSVEKMKEASSDFLFLFSSWCKFVFHFKFLQLFLSFLVPLFVALGLSYFSRKVLAH HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VNCYFTKGNEEISYLQRLLVAFISILLPLLVCVVCVYLVFFLFHSFGMELGKLTTIFYTV HEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH GHQIILVFLINRLALVLLSLNMVHVRLFNITPFVAHQLVILLTFLGGILAFDAVLDSIYQ HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH VVSASLSLTIAKSFIAVFLFAILLFIISFVPLRFRRKSSQNEERETHFLPLYIRIPFIVL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCEEEHHHHHHHHHH GLLLIVMDSLGYVGLAHFIMQQIVIGGAFLVLMYLGIKSAQVIGTKGQFMKTSVGHALMQ HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHH WFHLEEKTMNKLGIVISVVLNLIVVILCAMPIAVQFGFSYSDLRRVLLQVMTGFQIGNIS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHH VSLISIVIGIIAFFACWFLNRRFICWLDGMVLVHGEFDSGVRNSIKTVISYAGVVVSALI HHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH GLSMAGLDLKNFALIAGGLSLGIGFGLQNIVQNFVSGLIILIGRPFKLGDYVEAGSVGGI HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH VKRISVRATELETFQRKTIIIPNSSLINNNVSNWTRGSKMGRVDIPIVVSPNVAPERVVE HHHHHHHHHHHHHHCCCEEEECCCHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHH ILLEIASTTEGVLKNPAPQVSFTAFDSKKFSFSLAVYVPNITSSFKVTNALHFVLYKRFV HHHHHHHCCHHHHCCCCCCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHH QEGILEC HHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9278503; 10202137 [H]