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The map label for this gene is ssb4 [H]

Identifier: 49475757

GI number: 49475757

Start: 1123590

End: 1124108

Strand: Reverse

Name: ssb4 [H]

Synonym: BH10130

Alternate gene names: 49475757

Gene position: 1124108-1123590 (Counterclockwise)

Preceding gene: 49475762

Following gene: 49475756

Centisome position: 58.21

GC content: 39.5

Gene sequence:

>519_bases
ATGGCTGGTAGCCTTAATAAAGTTATTTTGATTGGTAATCTTGGCGCTGATCCTGAAATTCGCCGTTTGAATTCTGGTGA
TCAAGTGGCAAATTTGCGTATTGCGACTTCAGAGAGTTGGCGTGATCGTAATACAAATGAGCGTAAAGAGCGCACAGAAT
GGCATAATATCGTTATTTTTAACGAAAATCTTGTTAAAGTTGTAGAGCAATATTTAAAAAAAGGTAGTAAGATCTACATT
GAAGGTCAGTTGCAGACGCGTAAATGGCAAGATCAAAATGGTAATGATCGTTATACAACAGAGATTGTTTTGCAAAAATA
CCGCGGTGAGTTACAAATGCTTGATGGGCGCGCTGCAGCGGGGGGAGAACAAATGCAAGGAGCAAATCAGTCAAGCGGTG
CTTATAGCAGTGTTGGTTTTGGCGATAATAGCGCAAATCAGAGAGATGTTTTTGGTTCCAACAACAGTCAATTAGGAGAA
AGCTTTTCACACAAATTAGATGATGACGTACCTTTTTAA

Upstream 100 bases:

>100_bases
CCAATTGCAAATGTAGATAGGTAAATGGTAAGATTAAGATAGTAATGATCGTTATACAACAGAAATTGTTTTGCAAATTT
AAGACTTTGGAGTTTATAAG

Downstream 100 bases:

>100_bases
TGATTCTTAATAAGTGCTCTTATTCTTGCTCTTCGTATCTTTTTAGTTGTTTTTGTGAGGTTTTTTACGTTCAAAAAATT
AGATACTGTTGATTTTATCG

Product: single-strand binding protein (ssb)

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MAGSLNKVILIGNLGADPEIRRLNSGDQVANLRIATSESWRDRNTNERKERTEWHNIVIFNENLVKVVEQYLKKGSKIYI
EGQLQTRKWQDQNGNDRYTTEIVLQKYRGELQMLDGRAAAGGEQMQGANQSSGAYSSVGFGDNSANQRDVFGSNNSQLGE
SFSHKLDDDVPF

Sequences:

>Translated_172_residues
MAGSLNKVILIGNLGADPEIRRLNSGDQVANLRIATSESWRDRNTNERKERTEWHNIVIFNENLVKVVEQYLKKGSKIYI
EGQLQTRKWQDQNGNDRYTTEIVLQKYRGELQMLDGRAAAGGEQMQGANQSSGAYSSVGFGDNSANQRDVFGSNNSQLGE
SFSHKLDDDVPF
>Mature_171_residues
AGSLNKVILIGNLGADPEIRRLNSGDQVANLRIATSESWRDRNTNERKERTEWHNIVIFNENLVKVVEQYLKKGSKIYIE
GQLQTRKWQDQNGNDRYTTEIVLQKYRGELQMLDGRAAAGGEQMQGANQSSGAYSSVGFGDNSANQRDVFGSNNSQLGES
FSHKLDDDVPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=105, Percent_Identity=36.1904761904762, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1790494, Length=117, Percent_Identity=58.974358974359, Blast_Score=149, Evalue=8e-38,
Organism=Drosophila melanogaster, GI85725234, Length=103, Percent_Identity=33.9805825242718, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24647376, Length=103, Percent_Identity=33.9805825242718, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 19313; Mature: 19181

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSLNKVILIGNLGADPEIRRLNSGDQVANLRIATSESWRDRNTNERKERTEWHNIVIF
CCCCCCCEEEEECCCCCCHHEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCEEEEE
NENLVKVVEQYLKKGSKIYIEGQLQTRKWQDQNGNDRYTTEIVLQKYRGELQMLDGRAAA
CCHHHHHHHHHHHCCCEEEEEECEECCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCC
GGEQMQGANQSSGAYSSVGFGDNSANQRDVFGSNNSQLGESFSHKLDDDVPF
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AGSLNKVILIGNLGADPEIRRLNSGDQVANLRIATSESWRDRNTNERKERTEWHNIVIF
CCCCCCEEEEECCCCCCHHEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCEEEEE
NENLVKVVEQYLKKGSKIYIEGQLQTRKWQDQNGNDRYTTEIVLQKYRGELQMLDGRAAA
CCHHHHHHHHHHHCCCEEEEEECEECCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCC
GGEQMQGANQSSGAYSSVGFGDNSANQRDVFGSNNSQLGESFSHKLDDDVPF
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8225607 [H]