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The map label for this gene is glpX [H]

Identifier: 49475747

GI number: 49475747

Start: 1107135

End: 1108121

Strand: Reverse

Name: glpX [H]

Synonym: BH10020

Alternate gene names: 49475747

Gene position: 1108121-1107135 (Counterclockwise)

Preceding gene: 49475748

Following gene: 49475745

Centisome position: 57.38

GC content: 42.05

Gene sequence:

>987_bases
ATGCCCACAACTCAGAAAATTTTAAATGGACTTGATCGTATTCTAACGCTCGAGTTAGTACGTGTCACTGAACGGGCTGC
TGTTGCAGCTGCACGCTGGCGCGGGCGTGGTGATGAAAAGGCTGCTGATCAAGCAGCTGTAGATGCAATGCGTAAGGAAC
TTAATCGATTGCCTGTTGATGGTACAGTGGTGATTGGAGAGGGTGAACGTGATGAAGCTCCTATGCTTTATATTGGAGAA
AAAATAGGTCTTCAAAATGGATTGGCGATTGATATTGCACTTGACCCACTTGAAGGAACAACAATTTGTGCTAAAAATCT
TCCTAATTCTTTAGCTGTGGTTGCAATTGCTGAAAAGGGTAACCTCCTTTATGCCCCTGATGTTTATATGAAAAAAATTG
CTATTGGCCCTGGTTATCCAAAGGGGGTTGTTGATATAGATGCTTCTCCTACCGATAATATTTACGCCCTTGCAAAGGCT
AAGGGAGTGGTTGTTAATCAGATTACTGTTTGTATTATGGATCGACCTCGCCACGAAAAACTGATTAATGAAGTGCGATC
AACGGGGGCATCAATTCGCTTAATTGGTGATGGGGATGTTGCTGCCGTTATTGATACAACTGATCCAGATGAAACCGGCA
TTGATATCTATATGGGTATTGGTGGAGCACCAGAGGGTGTATTAGCTTCTGCAGCTTTACGCTGTATTGGTGGGCAGATG
CAAGGATGCTTGCTGCTTGATACAGACGAAAAAATTGCACGCGCGGCAAAAATGGGGATCGATAATCCTCATAAAGTTTA
TACAATGGAAGAAATGGCAAAGGGTGATGTTTTGTTTTCTGCAACAGGTGTAACAGATGGAAATATACTCTCTGGTGTTA
AATTCACCTCTCGTTATATTCAAACAGAAACCCTTGTGATGCGTTCACACACTGGTACAATTCGTAATATCAAAGCACAA
CATAGAGACCATTCAAAATTTGATTAA

Upstream 100 bases:

>100_bases
TTCTTGTAGAAAGTTCTCATCTTTGTCAAAAACTTTATTTAAAATGCTTTGCAATAAATATTCATGTTTTTTGCAGTACT
CATTCAGTAGGATTTTTCAT

Downstream 100 bases:

>100_bases
TCTCATCTTTTTCTGTGGCTATTAAAAATAGTAAAGTATCTTTTGAAAGTGTATGCTTCCATGAAGGTTCTAAGAGATGC
TCTCATGGAAGCATGAGGGT

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MPTTQKILNGLDRILTLELVRVTERAAVAAARWRGRGDEKAADQAAVDAMRKELNRLPVDGTVVIGEGERDEAPMLYIGE
KIGLQNGLAIDIALDPLEGTTICAKNLPNSLAVVAIAEKGNLLYAPDVYMKKIAIGPGYPKGVVDIDASPTDNIYALAKA
KGVVVNQITVCIMDRPRHEKLINEVRSTGASIRLIGDGDVAAVIDTTDPDETGIDIYMGIGGAPEGVLASAALRCIGGQM
QGCLLLDTDEKIARAAKMGIDNPHKVYTMEEMAKGDVLFSATGVTDGNILSGVKFTSRYIQTETLVMRSHTGTIRNIKAQ
HRDHSKFD

Sequences:

>Translated_328_residues
MPTTQKILNGLDRILTLELVRVTERAAVAAARWRGRGDEKAADQAAVDAMRKELNRLPVDGTVVIGEGERDEAPMLYIGE
KIGLQNGLAIDIALDPLEGTTICAKNLPNSLAVVAIAEKGNLLYAPDVYMKKIAIGPGYPKGVVDIDASPTDNIYALAKA
KGVVVNQITVCIMDRPRHEKLINEVRSTGASIRLIGDGDVAAVIDTTDPDETGIDIYMGIGGAPEGVLASAALRCIGGQM
QGCLLLDTDEKIARAAKMGIDNPHKVYTMEEMAKGDVLFSATGVTDGNILSGVKFTSRYIQTETLVMRSHTGTIRNIKAQ
HRDHSKFD
>Mature_327_residues
PTTQKILNGLDRILTLELVRVTERAAVAAARWRGRGDEKAADQAAVDAMRKELNRLPVDGTVVIGEGERDEAPMLYIGEK
IGLQNGLAIDIALDPLEGTTICAKNLPNSLAVVAIAEKGNLLYAPDVYMKKIAIGPGYPKGVVDIDASPTDNIYALAKAK
GVVVNQITVCIMDRPRHEKLINEVRSTGASIRLIGDGDVAAVIDTTDPDETGIDIYMGIGGAPEGVLASAALRCIGGQMQ
GCLLLDTDEKIARAAKMGIDNPHKVYTMEEMAKGDVLFSATGVTDGNILSGVKFTSRYIQTETLVMRSHTGTIRNIKAQH
RDHSKFD

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=325, Percent_Identity=46.1538461538462, Blast_Score=267, Evalue=6e-73,
Organism=Escherichia coli, GI1789298, Length=321, Percent_Identity=40.1869158878505, Blast_Score=212, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35164; Mature: 35033

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTTQKILNGLDRILTLELVRVTERAAVAAARWRGRGDEKAADQAAVDAMRKELNRLPVD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
GTVVIGEGERDEAPMLYIGEKIGLQNGLAIDIALDPLEGTTICAKNLPNSLAVVAIAEKG
CEEEEECCCCCCCCEEEEEHHCCCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEECCC
NLLYAPDVYMKKIAIGPGYPKGVVDIDASPTDNIYALAKAKGVVVNQITVCIMDRPRHEK
CEEECCCHHEEEEECCCCCCCCEEEECCCCCCCEEEEEECCCEEEEEEEEEEECCCHHHH
LINEVRSTGASIRLIGDGDVAAVIDTTDPDETGIDIYMGIGGAPEGVLASAALRCIGGQM
HHHHHHHCCCEEEEEECCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCC
QGCLLLDTDEKIARAAKMGIDNPHKVYTMEEMAKGDVLFSATGVTDGNILSGVKFTSRYI
CCEEEEECCHHHHHHHHHCCCCCCEEEEHHHHCCCCEEEEECCCCCCCHHCCHHHHHHHH
QTETLVMRSHTGTIRNIKAQHRDHSKFD
HHEEEEEECCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PTTQKILNGLDRILTLELVRVTERAAVAAARWRGRGDEKAADQAAVDAMRKELNRLPVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
GTVVIGEGERDEAPMLYIGEKIGLQNGLAIDIALDPLEGTTICAKNLPNSLAVVAIAEKG
CEEEEECCCCCCCCEEEEEHHCCCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEECCC
NLLYAPDVYMKKIAIGPGYPKGVVDIDASPTDNIYALAKAKGVVVNQITVCIMDRPRHEK
CEEECCCHHEEEEECCCCCCCCEEEECCCCCCCEEEEEECCCEEEEEEEEEEECCCHHHH
LINEVRSTGASIRLIGDGDVAAVIDTTDPDETGIDIYMGIGGAPEGVLASAALRCIGGQM
HHHHHHHCCCEEEEEECCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCC
QGCLLLDTDEKIARAAKMGIDNPHKVYTMEEMAKGDVLFSATGVTDGNILSGVKFTSRYI
CCEEEEECCHHHHHHHHHCCCCCCEEEEHHHHCCCCEEEEECCCCCCCHHCCHHHHHHHH
QTETLVMRSHTGTIRNIKAQHRDHSKFD
HHEEEEEECCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]