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The map label for this gene is ydhC [H]

Identifier: 49475665

GI number: 49475665

Start: 1015844

End: 1016674

Strand: Reverse

Name: ydhC [H]

Synonym: BH09050

Alternate gene names: 49475665

Gene position: 1016674-1015844 (Counterclockwise)

Preceding gene: 49475666

Following gene: 49475664

Centisome position: 52.65

GC content: 35.74

Gene sequence:

>831_bases
ATGGATAAAAAGGCTGCAGGAAAGCTTTATTTGGTTATTTTTCCCTTTGTTGGCACATCACCAGCAATAGCTCCATTCGT
TGGGGGGATTTTATTACAAGCTTTTAATTGGCAAGCCACTTTTATCTTTTTAAGCCTTTTTATACTTTTAATCATTCTGC
TCTGTTATTTTGTATTAACAGAGACTCTCCCTCCTATAAAACGTCAATCTTTTACTTCTGTGGGAATTATTAAGAGCAGT
ATAAGAATTCTTAGAAATAAACAATTTATCTTTTATGCTGTAATCCCATGTTTTGCATACGCAACCTATTTTGCTTACAT
TGTAGAATCACCTTTTTTCCTCACAGCTTTGGGCTTATCAACTTTATATATTGGTTATAGTTACATTGGTGTTTCTTTAA
CTTATGTTCTAGGTAACCTAGTAGCGCGAATGTTTCTTAAGCAAGAATCCATGGAACGTGCTGTTCGGCGTGGATATGTT
ATTTTTGTCTTGGGAGGGGTGTTATTTGCCCTACAAATGTATATAAGTCCATGGCCATTTGTAACAAGTTTAATAACCAT
TTCTATTCTTACTTTTGGCAATGGTTTTTTGTTACCGTTAGGAACAACTTTGGCAACTTCATCTCATCCACAAGCTGCTG
GAGCGGCATCTGGTGTTATGGGAGCTTTGCAATTAGGAAGTGCTGCACTGAGCTTTGCGGTTATTGGGAAAATGTCCGAA
CATAATCCATGGAGTGTCGCCGTTTTATTAGCAACATGCTGTATCGTGGGTTTTATAATTTACATTCGAAAAGCAAATTA
TTTTATTAATTTAGAAAAACAATCAAGCTAA

Upstream 100 bases:

>100_bases
TAACATTAACAGTTATAATAAAAAAACTAATACTATCGTATTATCAAAAAAAGAAATTTGTTCTGAAAGTTTAGAACCTA
TCGATTTGGTTGATGATTTG

Downstream 100 bases:

>100_bases
ATAACCAACTTGGGGGGGACTATGCTTAAAAATCTTGATGTTACTTTGTGTGACGGAGGATACAGGAATCAGTTTTCTTT
TTCATTAGATTACGTTATTG

Product: transport protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MDKKAAGKLYLVIFPFVGTSPAIAPFVGGILLQAFNWQATFIFLSLFILLIILLCYFVLTETLPPIKRQSFTSVGIIKSS
IRILRNKQFIFYAVIPCFAYATYFAYIVESPFFLTALGLSTLYIGYSYIGVSLTYVLGNLVARMFLKQESMERAVRRGYV
IFVLGGVLFALQMYISPWPFVTSLITISILTFGNGFLLPLGTTLATSSHPQAAGAASGVMGALQLGSAALSFAVIGKMSE
HNPWSVAVLLATCCIVGFIIYIRKANYFINLEKQSS

Sequences:

>Translated_276_residues
MDKKAAGKLYLVIFPFVGTSPAIAPFVGGILLQAFNWQATFIFLSLFILLIILLCYFVLTETLPPIKRQSFTSVGIIKSS
IRILRNKQFIFYAVIPCFAYATYFAYIVESPFFLTALGLSTLYIGYSYIGVSLTYVLGNLVARMFLKQESMERAVRRGYV
IFVLGGVLFALQMYISPWPFVTSLITISILTFGNGFLLPLGTTLATSSHPQAAGAASGVMGALQLGSAALSFAVIGKMSE
HNPWSVAVLLATCCIVGFIIYIRKANYFINLEKQSS
>Mature_276_residues
MDKKAAGKLYLVIFPFVGTSPAIAPFVGGILLQAFNWQATFIFLSLFILLIILLCYFVLTETLPPIKRQSFTSVGIIKSS
IRILRNKQFIFYAVIPCFAYATYFAYIVESPFFLTALGLSTLYIGYSYIGVSLTYVLGNLVARMFLKQESMERAVRRGYV
IFVLGGVLFALQMYISPWPFVTSLITISILTFGNGFLLPLGTTLATSSHPQAAGAASGVMGALQLGSAALSFAVIGKMSE
HNPWSVAVLLATCCIVGFIIYIRKANYFINLEKQSS

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=225, Percent_Identity=29.3333333333333, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 30298; Mature: 30298

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKAAGKLYLVIFPFVGTSPAIAPFVGGILLQAFNWQATFIFLSLFILLIILLCYFVLT
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ETLPPIKRQSFTSVGIIKSSIRILRNKQFIFYAVIPCFAYATYFAYIVESPFFLTALGLS
HCCCCCHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TLYIGYSYIGVSLTYVLGNLVARMFLKQESMERAVRRGYVIFVLGGVLFALQMYISPWPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHH
VTSLITISILTFGNGFLLPLGTTLATSSHPQAAGAASGVMGALQLGSAALSFAVIGKMSE
HHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
HNPWSVAVLLATCCIVGFIIYIRKANYFINLEKQSS
CCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
>Mature Secondary Structure
MDKKAAGKLYLVIFPFVGTSPAIAPFVGGILLQAFNWQATFIFLSLFILLIILLCYFVLT
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ETLPPIKRQSFTSVGIIKSSIRILRNKQFIFYAVIPCFAYATYFAYIVESPFFLTALGLS
HCCCCCHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TLYIGYSYIGVSLTYVLGNLVARMFLKQESMERAVRRGYVIFVLGGVLFALQMYISPWPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHH
VTSLITISILTFGNGFLLPLGTTLATSSHPQAAGAASGVMGALQLGSAALSFAVIGKMSE
HHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
HNPWSVAVLLATCCIVGFIIYIRKANYFINLEKQSS
CCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]