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The map label for this gene is nuoC

Identifier: 49475656

GI number: 49475656

Start: 1009622

End: 1010230

Strand: Reverse

Name: nuoC

Synonym: BH08930

Alternate gene names: 49475656

Gene position: 1010230-1009622 (Counterclockwise)

Preceding gene: 49475657

Following gene: 49475655

Centisome position: 52.32

GC content: 38.59

Gene sequence:

>609_bases
ATGAGTGAATCATTAGAAGAGCTTGCTGCCTATTTGAAAAGCAAGCTAGGAGATAAGCTTGAAGAAACTGTTCTTGCATT
TGGAGAGTTGACTATTGTATCGCGCCTTGATGCAATTACGGATGTCTTAATATTTGTTCGTGATGATTCTCGTTGTCAGT
TTATTAATATTACAGACATTAGTGGTGTTGATTATCCTTGTCGCGATAAACGTTTTGATGTCTCTTATCAACTCTTATCT
CCTCGCCATAATTTACGGTTGCGTGTTAAGGTGCGTACTGATGAAAACATTCCCGTTGCTTCTGCTTGCTCGATTTATCC
TGGAGCAGAATGGTATGAGCGTGAAACGTACGATATGTATGGGATTTTATTTTCAGGTCATCCAGATTTAAGACGAATCT
TAACTGATTATGGATTTGAAGGTCATCCTCTACGTAAAGATTTTCCTGTGACGGGATTTGTCGAATGCCGTTATGATAAT
GAAGCAAAGAGGGTGATTTATGAGCCTGTTGTTTTGCGGCAAGAAATGCGGAATTTTGATTTTCTTTCTCCTTGGGAGGG
AGCGCAATATATTTTGCCATGTGATGAGAAAACAAAGGATAAAAGATAA

Upstream 100 bases:

>100_bases
TGTCCTCCTACAGCAGAGGCATTACTATATGGTATATTGTTGTTGCAGAAAAAAATCCGTCGTACCGGATCGATAGAGCG
ATAGGGAGCTTTTGTTGTTG

Downstream 100 bases:

>100_bases
TATTGGAGTTGGCAAAATACAGAGTTATAGTAGTAAGATTCTCAAATAACTAAATATTTTCAATATAATGAGGATTTTTA
TTAAAGTTTGATATAAAGTT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSESLEELAAYLKSKLGDKLEETVLAFGELTIVSRLDAITDVLIFVRDDSRCQFINITDISGVDYPCRDKRFDVSYQLLS
PRHNLRLRVKVRTDENIPVASACSIYPGAEWYERETYDMYGILFSGHPDLRRILTDYGFEGHPLRKDFPVTGFVECRYDN
EAKRVIYEPVVLRQEMRNFDFLSPWEGAQYILPCDEKTKDKR

Sequences:

>Translated_202_residues
MSESLEELAAYLKSKLGDKLEETVLAFGELTIVSRLDAITDVLIFVRDDSRCQFINITDISGVDYPCRDKRFDVSYQLLS
PRHNLRLRVKVRTDENIPVASACSIYPGAEWYERETYDMYGILFSGHPDLRRILTDYGFEGHPLRKDFPVTGFVECRYDN
EAKRVIYEPVVLRQEMRNFDFLSPWEGAQYILPCDEKTKDKR
>Mature_201_residues
SESLEELAAYLKSKLGDKLEETVLAFGELTIVSRLDAITDVLIFVRDDSRCQFINITDISGVDYPCRDKRFDVSYQLLSP
RHNLRLRVKVRTDENIPVASACSIYPGAEWYERETYDMYGILFSGHPDLRRILTDYGFEGHPLRKDFPVTGFVECRYDNE
AKRVIYEPVVLRQEMRNFDFLSPWEGAQYILPCDEKTKDKR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=186, Percent_Identity=50.5376344086022, Blast_Score=201, Evalue=4e-52,
Organism=Escherichia coli, GI145693162, Length=146, Percent_Identity=33.5616438356164, Blast_Score=87, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32563621, Length=185, Percent_Identity=48.6486486486487, Blast_Score=189, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI71990788, Length=185, Percent_Identity=48.6486486486487, Blast_Score=189, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24656494, Length=183, Percent_Identity=51.9125683060109, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_BARHE (Q6G390)

Other databases:

- EMBL:   BX897699
- RefSeq:   YP_033697.1
- ProteinModelPortal:   Q6G390
- SMR:   Q6G390
- GeneID:   2864976
- GenomeReviews:   BX897699_GR
- KEGG:   bhe:BH08930
- NMPDR:   fig|283166.1.peg.825
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   PRK06074
- BioCyc:   BHEN283166:BH08930-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 23566; Mature: 23435

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESLEELAAYLKSKLGDKLEETVLAFGELTIVSRLDAITDVLIFVRDDSRCQFINITDI
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEEEECC
SGVDYPCRDKRFDVSYQLLSPRHNLRLRVKVRTDENIPVASACSIYPGAEWYERETYDMY
CCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHCCCCCCCCHHHCCCCEEEE
GILFSGHPDLRRILTDYGFEGHPLRKDFPVTGFVECRYDNEAKRVIYEPVVLRQEMRNFD
EEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCC
FLSPWEGAQYILPCDEKTKDKR
CCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
SESLEELAAYLKSKLGDKLEETVLAFGELTIVSRLDAITDVLIFVRDDSRCQFINITDI
CHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEEEECC
SGVDYPCRDKRFDVSYQLLSPRHNLRLRVKVRTDENIPVASACSIYPGAEWYERETYDMY
CCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCHHCCCCCCCCHHHCCCCEEEE
GILFSGHPDLRRILTDYGFEGHPLRKDFPVTGFVECRYDNEAKRVIYEPVVLRQEMRNFD
EEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCC
FLSPWEGAQYILPCDEKTKDKR
CCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA