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The map label for this gene is sufC [H]

Identifier: 49475626

GI number: 49475626

Start: 966977

End: 967732

Strand: Reverse

Name: sufC [H]

Synonym: BH08630

Alternate gene names: 49475626

Gene position: 967732-966977 (Counterclockwise)

Preceding gene: 49475627

Following gene: 49475625

Centisome position: 50.11

GC content: 36.64

Gene sequence:

>756_bases
ATGTTAGAGATAAAAGGTTTACGTGCCCGTATTGTTGGGACCAATACAGAAGTTATTCGTGGTTTAAACTTGACTGTTGC
AGATGGTGAAGTTGCTGCTATCATGGGACAGAATGGGGCTGGAAAGTCTACCTTGTCTTATTTACTTGCTGGTCGTGATG
ATTATGAAGTGATAGATGGCGATATTCTTTATAATGGACAATCACTTTTAGAAATGGATCCAGCAGAGCGTGCTGCATAC
GGTGTTTTTCTTGCATTTCAATATCCAATGGAAATACCTGGAGTAGCAACGATGGAATTTTTAAAAGTTGCGATGAATTC
TCAACGCAAAGCGCGTGGTGATCAAGAACTCAAAATTCCTGAATTTATAAAATGTGTTAAGGAAATTTCTTCCAAACTTG
AAATAAATATGGATATGCTCAAACGTCCGTTAAATGTAGGTTTTTCAGGTGGAGAAAAAAAACGTGCTGAAATTTTACAA
ATGGCGCTTCTTGAACCTAAACTTTGTATTTTAGATGAAACGGACTCTGGTTTAGATATTGATGCACTAAAAATTGTTGC
AGATGGTGTCAATAAGCTCCGTGATCCAAAGCGTTCATTTTTGGTTATTACTCATTATCAACGCCTGCTTAATTATATTA
TTCCTGATACGGTACATGTTCTTTATAAAGGACGTATTATTAAAAGCGGAGATAAATCATTAGCGCTTTATCTAGAACAG
AACGGATATGCTGATCTTATCAGAGAAGCAGCTTGA

Upstream 100 bases:

>100_bases
CAGAAGCTTATTGGTATCAGTCTTGAGGGTAGTGTGGGATAATTGTTTTAAGTAAAGAAGCACACTTTTAACATACAACA
GCCAGAACAGGAATTAAATG

Downstream 100 bases:

>100_bases
GGTCATCAAATATGAATGTAAATTCGCAGCAAGAATTGTTAACGGTTGAAGAAGATATACTCAAGAATTTCAATCAGTAT
GTGAGCAATTTACCTGGTGA

Product: ATP-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLEIKGLRARIVGTNTEVIRGLNLTVADGEVAAIMGQNGAGKSTLSYLLAGRDDYEVIDGDILYNGQSLLEMDPAERAAY
GVFLAFQYPMEIPGVATMEFLKVAMNSQRKARGDQELKIPEFIKCVKEISSKLEINMDMLKRPLNVGFSGGEKKRAEILQ
MALLEPKLCILDETDSGLDIDALKIVADGVNKLRDPKRSFLVITHYQRLLNYIIPDTVHVLYKGRIIKSGDKSLALYLEQ
NGYADLIREAA

Sequences:

>Translated_251_residues
MLEIKGLRARIVGTNTEVIRGLNLTVADGEVAAIMGQNGAGKSTLSYLLAGRDDYEVIDGDILYNGQSLLEMDPAERAAY
GVFLAFQYPMEIPGVATMEFLKVAMNSQRKARGDQELKIPEFIKCVKEISSKLEINMDMLKRPLNVGFSGGEKKRAEILQ
MALLEPKLCILDETDSGLDIDALKIVADGVNKLRDPKRSFLVITHYQRLLNYIIPDTVHVLYKGRIIKSGDKSLALYLEQ
NGYADLIREAA
>Mature_251_residues
MLEIKGLRARIVGTNTEVIRGLNLTVADGEVAAIMGQNGAGKSTLSYLLAGRDDYEVIDGDILYNGQSLLEMDPAERAAY
GVFLAFQYPMEIPGVATMEFLKVAMNSQRKARGDQELKIPEFIKCVKEISSKLEINMDMLKRPLNVGFSGGEKKRAEILQ
MALLEPKLCILDETDSGLDIDALKIVADGVNKLRDPKRSFLVITHYQRLLNYIIPDTVHVLYKGRIIKSGDKSLALYLEQ
NGYADLIREAA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=239, Percent_Identity=28.8702928870293, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI148612844, Length=222, Percent_Identity=30.1801801801802, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI255708477, Length=222, Percent_Identity=30.1801801801802, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI9961252, Length=225, Percent_Identity=28.4444444444444, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4505771, Length=225, Percent_Identity=28.4444444444444, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI9961250, Length=225, Percent_Identity=28.4444444444444, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI42741659, Length=221, Percent_Identity=28.0542986425339, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787972, Length=249, Percent_Identity=57.0281124497992, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI87082267, Length=193, Percent_Identity=32.6424870466321, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081834, Length=196, Percent_Identity=27.5510204081633, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789891, Length=221, Percent_Identity=30.316742081448, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787500, Length=222, Percent_Identity=28.8288288288288, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48995001, Length=206, Percent_Identity=27.1844660194175, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787758, Length=247, Percent_Identity=25.5060728744939, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=234, Percent_Identity=24.7863247863248, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI48994883, Length=257, Percent_Identity=26.0700389105058, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787370, Length=235, Percent_Identity=25.1063829787234, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789963, Length=240, Percent_Identity=24.5833333333333, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789864, Length=238, Percent_Identity=24.7899159663866, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790467, Length=222, Percent_Identity=28.3783783783784, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789962, Length=230, Percent_Identity=26.9565217391304, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790525, Length=190, Percent_Identity=27.8947368421053, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788897, Length=188, Percent_Identity=29.2553191489362, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=234, Percent_Identity=26.0683760683761, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=213, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71984940, Length=224, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=218, Percent_Identity=28.4403669724771, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71992290, Length=240, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17543740, Length=188, Percent_Identity=30.3191489361702, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319856, Length=236, Percent_Identity=27.9661016949153, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27854; Mature: 27854

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIKGLRARIVGTNTEVIRGLNLTVADGEVAAIMGQNGAGKSTLSYLLAGRDDYEVIDG
CCCCCCCEEEEEECCHHHHCCCEEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCEEECC
DILYNGQSLLEMDPAERAAYGVFLAFQYPMEIPGVATMEFLKVAMNSQRKARGDQELKIP
EEEECCCHHEECCCHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCH
EFIKCVKEISSKLEINMDMLKRPLNVGFSGGEKKRAEILQMALLEPKLCILDETDSGLDI
HHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCH
DALKIVADGVNKLRDPKRSFLVITHYQRLLNYIIPDTVHVLYKGRIIKSGDKSLALYLEQ
HHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHCCHHEEEHEECEEEECCCCEEEEEEEC
NGYADLIREAA
CCHHHHHHHCC
>Mature Secondary Structure
MLEIKGLRARIVGTNTEVIRGLNLTVADGEVAAIMGQNGAGKSTLSYLLAGRDDYEVIDG
CCCCCCCEEEEEECCHHHHCCCEEEEECCCEEEEECCCCCCHHHHHHHHCCCCCCEEECC
DILYNGQSLLEMDPAERAAYGVFLAFQYPMEIPGVATMEFLKVAMNSQRKARGDQELKIP
EEEECCCHHEECCCHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCH
EFIKCVKEISSKLEINMDMLKRPLNVGFSGGEKKRAEILQMALLEPKLCILDETDSGLDI
HHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCH
DALKIVADGVNKLRDPKRSFLVITHYQRLLNYIIPDTVHVLYKGRIIKSGDKSLALYLEQ
HHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHHHCCHHEEEHEECEEEECCCCEEEEEEEC
NGYADLIREAA
CCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]