Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 49475524

GI number: 49475524

Start: 867350

End: 868285

Strand: Reverse

Name: argC [H]

Synonym: BH07530

Alternate gene names: 49475524

Gene position: 868285-867350 (Counterclockwise)

Preceding gene: 49475531

Following gene: 49475519

Centisome position: 44.96

GC content: 38.57

Gene sequence:

>936_bases
ATGGCAACGAAAGTTTTTATTGATGGTGAACATGGAACAACTGGTTTACAGATACAAAAGCGACTAGCGAAGCGTTCAGA
TGTAGAATTACTCTCTCTTCCTCATAGAGATCGGTATAATATTGATATTCGAAAAGATTATTTTAATCAAACTGATATTG
CTATTTTGTGTCTTCCAGATGAAGCCGCGCGCGAAACAGTTCACTGGCTTAAAAAAAATAAAAAAATTAGAATTATTGAT
AGCTCAACAGCCCACCGTGTTGCACCAAACTGGGTCTATGGTTTTCCTGAAATGACAGCTGGCCAAAAAGAACGTATCCA
AGCAGCACACTACGTAACCAATCCCGGATGTTACCCTACCGGTGCAATTAGCTTGATTCGCCCCCTACGTGAAGCAGGCC
TGCTAGACGCTTATTATCCAATATCAATTAACGCAATATCTGGTTATACTGGTGGCGGTAGAAAATTAATTGCACAAATG
GAAAATCAATCTCGACAAGATGACGTTCGAGAAAATTATTTCATCTATGGCCTCAACCTTAAACACAAACATGTGCCAGA
AATTAAAATCCATGGGCAAATCAGCCACACACCCATTTTTGTACCAAGTGTTGGTCGTTTTCCTCAAGGAATGATTGTAA
ATATTCCACTGCATCGCCATTTATTTACAAAATCAGCAAATTCTTCTGATATACACGAAATTCTTGCAAATCATTACGAT
GGACAAAACATGATTTCAATTGCGTCACAAAAAGAAACTGATTCGCTTAATAAACTCAATCCAGAATGCTTAGCGCATAA
AGATGGTATGAAACTGTTTGTTTTTGGCAATGACAGCGAAGGAATTTTCAATCTCTGTGCCATATTCGACAATTTAGGGA
AAGGTGCCTCAGCAGCTGCAATCCAAAATCTCGATTTAATGCTGTCACAGAGCTAA

Upstream 100 bases:

>100_bases
TACAAGAAAGAAACCGCCACCTTAAGAAATTCAATCGTCTATGCTGATTTATAACGCAACAAGCTATATAAGACAGAAAA
ATTAATTCAAGGCAAAAAGA

Downstream 100 bases:

>100_bases
ACTTCTCTAAGTTTAGACTTTTATTCAATAGCACGATACGCCCCTTTTGTTGCTCGCCAGTGTGCAACCGAAAAACACAA
TATCGCTAACGCAACACTTT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MATKVFIDGEHGTTGLQIQKRLAKRSDVELLSLPHRDRYNIDIRKDYFNQTDIAILCLPDEAARETVHWLKKNKKIRIID
SSTAHRVAPNWVYGFPEMTAGQKERIQAAHYVTNPGCYPTGAISLIRPLREAGLLDAYYPISINAISGYTGGGRKLIAQM
ENQSRQDDVRENYFIYGLNLKHKHVPEIKIHGQISHTPIFVPSVGRFPQGMIVNIPLHRHLFTKSANSSDIHEILANHYD
GQNMISIASQKETDSLNKLNPECLAHKDGMKLFVFGNDSEGIFNLCAIFDNLGKGASAAAIQNLDLMLSQS

Sequences:

>Translated_311_residues
MATKVFIDGEHGTTGLQIQKRLAKRSDVELLSLPHRDRYNIDIRKDYFNQTDIAILCLPDEAARETVHWLKKNKKIRIID
SSTAHRVAPNWVYGFPEMTAGQKERIQAAHYVTNPGCYPTGAISLIRPLREAGLLDAYYPISINAISGYTGGGRKLIAQM
ENQSRQDDVRENYFIYGLNLKHKHVPEIKIHGQISHTPIFVPSVGRFPQGMIVNIPLHRHLFTKSANSSDIHEILANHYD
GQNMISIASQKETDSLNKLNPECLAHKDGMKLFVFGNDSEGIFNLCAIFDNLGKGASAAAIQNLDLMLSQS
>Mature_310_residues
ATKVFIDGEHGTTGLQIQKRLAKRSDVELLSLPHRDRYNIDIRKDYFNQTDIAILCLPDEAARETVHWLKKNKKIRIIDS
STAHRVAPNWVYGFPEMTAGQKERIQAAHYVTNPGCYPTGAISLIRPLREAGLLDAYYPISINAISGYTGGGRKLIAQME
NQSRQDDVRENYFIYGLNLKHKHVPEIKIHGQISHTPIFVPSVGRFPQGMIVNIPLHRHLFTKSANSSDIHEILANHYDG
QNMISIASQKETDSLNKLNPECLAHKDGMKLFVFGNDSEGIFNLCAIFDNLGKGASAAAIQNLDLMLSQS

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=124, Percent_Identity=36.2903225806452, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320913, Length=282, Percent_Identity=28.7234042553192, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 34847; Mature: 34716

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKVFIDGEHGTTGLQIQKRLAKRSDVELLSLPHRDRYNIDIRKDYFNQTDIAILCLPD
CCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCCCEEEEECCC
EAARETVHWLKKNKKIRIIDSSTAHRVAPNWVYGFPEMTAGQKERIQAAHYVTNPGCYPT
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHEECCCCCCCC
GAISLIRPLREAGLLDAYYPISINAISGYTGGGRKLIAQMENQSRQDDVRENYFIYGLNL
HHHHHHHHHHHCCCEEEECCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHCCEEEEEECC
KHKHVPEIKIHGQISHTPIFVPSVGRFPQGMIVNIPLHRHLFTKSANSSDIHEILANHYD
CCCCCCEEEEEEEECCCCEECCCCCCCCCCEEEEECHHHHHHHCCCCCHHHHHHHHHCCC
GQNMISIASQKETDSLNKLNPECLAHKDGMKLFVFGNDSEGIFNLCAIFDNLGKGASAAA
CCCEEEECCCCCCCHHHCCCHHHEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCHHH
IQNLDLMLSQS
HCCEEEEEECC
>Mature Secondary Structure 
ATKVFIDGEHGTTGLQIQKRLAKRSDVELLSLPHRDRYNIDIRKDYFNQTDIAILCLPD
CEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCCCEEEEECCC
EAARETVHWLKKNKKIRIIDSSTAHRVAPNWVYGFPEMTAGQKERIQAAHYVTNPGCYPT
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHEECCCCCCCC
GAISLIRPLREAGLLDAYYPISINAISGYTGGGRKLIAQMENQSRQDDVRENYFIYGLNL
HHHHHHHHHHHCCCEEEECCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHCCEEEEEECC
KHKHVPEIKIHGQISHTPIFVPSVGRFPQGMIVNIPLHRHLFTKSANSSDIHEILANHYD
CCCCCCEEEEEEEECCCCEECCCCCCCCCCEEEEECHHHHHHHCCCCCHHHHHHHHHCCC
GQNMISIASQKETDSLNKLNPECLAHKDGMKLFVFGNDSEGIFNLCAIFDNLGKGASAAA
CCCEEEECCCCCCCHHHCCCHHHEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCHHH
IQNLDLMLSQS
HCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA