Click here to switch to the map view.

The map label for this gene is fabF3 [C]

Identifier: 49475516

GI number: 49475516

Start: 852426

End: 853601

Strand: Reverse

Name: fabF3 [C]

Synonym: BH07450

Alternate gene names: 49475516

Gene position: 853601-852426 (Counterclockwise)

Preceding gene: 49475517

Following gene: 49475515

Centisome position: 44.2

GC content: 40.05

Gene sequence:

>1176_bases
ATGCATGATCAAACAGTATTCATCACTGGTATAGGATTGATAACCTCTTTGGGTGAAGGGGTTGAGCATCATTGGGATAT
ATTGAATAACACAACCCTTACACCAAATCTTGATTGTACAACTTTCTCCCCCTACACTATCCATAAATTGCCCGAAATCA
ACTGGGGTTTGCAAATTCCAAAACGAAGCGATCAACGGCAAATGGGAACGTGGCAACGTCTTGGGACTTATGCAGCGGGC
CTTGCTCTTGATGATGCAGGTATAAAGAATAATGAACAATTAACGTCAACAATGGATATGATTGTTGCAGCAGGTGGAGG
AGAACGTGACATTGATGTTGACACACAAATTCTTTCCAAAGCACGTATAGGAGCTGATCATGCTTCTATGTTAAATTCAA
TCCTTTCAACTGAACTTCGTCCAACTCTGTTTTTAGCACAACTTTCAAATCTTTTAGCTGGAAATATTTCAATTGTTCAT
AAAGTAACCGGATCTTCTCGTACCTTCATGGGAGAAGAAGGGTGTGGGCTTTCTGCATTTCAAATTGCTGTAGCTCGTAT
TCGATCAGGACAAAGTACACATGTATTGGTAGGAAGCTCTTATAATGCACAAGGCTATGATATGCTGTTAGCGCATGAAC
TTGGAGGTCTCTTATCACGCAGTGGATGGTCGCCAGTATGGGATCGTAAAAATTGCCTTGGTGGTGGTATTATAACGGGT
TCTGGTGGTATCTTTCTAGTCCTTGAAAATGGGAAACATGCGAAAAAACGTAATGCACGTGCTTATGCTGAAATTAGCCA
GATCATCACGGATCAAACAGACAGAACAAATATTCCACTTGAAAAATCCATTGCAACACTGTTGAAAACAGTAGGAGCTA
AAAATTCTTTAGTCATTTCAGCGGCTTCAGGATTTCATGAAGTGACCAAAGCAGAACAAAATGCTCTTGAGGCTAATGAT
ATGTTTTACCGCGGTATCACAACATTATTTGGTTATATGCGGGAAGCACAATTTCCTTTAGCTCTCGCACTTGCTGCACT
TTCTATTGAAAAAAAACGCTGTTTTCCAGCATTCAGTGCTCATGAAAAACCTTTTCCTAAAGAAATACGTGAAGCATTTG
TTACAACCATTGGTATCAAAAGAGCTGAAGGTATAGCACAGCTAACTGCTGTATAA

Upstream 100 bases:

>100_bases
AAGGTACAGTTGCAACTGAAGAATACTTTGTTCTTAAAAATCTTTGCGCAAAAATTGATGAACTCGTTGCTTTAAAACAA
GAGAATTAATTTCTTTTATC

Downstream 100 bases:

>100_bases
GGGGATTTCTACAATGCAATATAACGATCATTTTGGACGTCCAATTGTAGCAATAACTGGAGCAGGAATTGTAACATCAC
TGGGGAAAGGTAAACACGAA

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: Beta-Ketoacyl Synthase; 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase II; 3-Oxoacyl-[Acyl-Carrier-Protein] Synthase II Protein; 3-Oxoacyl-(ACP) Synthase III; 3-Oxoacyl-(Acyl-Acp) Synthase II Protein; 3-Oxoacyl-[Acyl-Carrier-Protein] Synthase II

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MHDQTVFITGIGLITSLGEGVEHHWDILNNTTLTPNLDCTTFSPYTIHKLPEINWGLQIPKRSDQRQMGTWQRLGTYAAG
LALDDAGIKNNEQLTSTMDMIVAAGGGERDIDVDTQILSKARIGADHASMLNSILSTELRPTLFLAQLSNLLAGNISIVH
KVTGSSRTFMGEEGCGLSAFQIAVARIRSGQSTHVLVGSSYNAQGYDMLLAHELGGLLSRSGWSPVWDRKNCLGGGIITG
SGGIFLVLENGKHAKKRNARAYAEISQIITDQTDRTNIPLEKSIATLLKTVGAKNSLVISAASGFHEVTKAEQNALEAND
MFYRGITTLFGYMREAQFPLALALAALSIEKKRCFPAFSAHEKPFPKEIREAFVTTIGIKRAEGIAQLTAV

Sequences:

>Translated_391_residues
MHDQTVFITGIGLITSLGEGVEHHWDILNNTTLTPNLDCTTFSPYTIHKLPEINWGLQIPKRSDQRQMGTWQRLGTYAAG
LALDDAGIKNNEQLTSTMDMIVAAGGGERDIDVDTQILSKARIGADHASMLNSILSTELRPTLFLAQLSNLLAGNISIVH
KVTGSSRTFMGEEGCGLSAFQIAVARIRSGQSTHVLVGSSYNAQGYDMLLAHELGGLLSRSGWSPVWDRKNCLGGGIITG
SGGIFLVLENGKHAKKRNARAYAEISQIITDQTDRTNIPLEKSIATLLKTVGAKNSLVISAASGFHEVTKAEQNALEAND
MFYRGITTLFGYMREAQFPLALALAALSIEKKRCFPAFSAHEKPFPKEIREAFVTTIGIKRAEGIAQLTAV
>Mature_391_residues
MHDQTVFITGIGLITSLGEGVEHHWDILNNTTLTPNLDCTTFSPYTIHKLPEINWGLQIPKRSDQRQMGTWQRLGTYAAG
LALDDAGIKNNEQLTSTMDMIVAAGGGERDIDVDTQILSKARIGADHASMLNSILSTELRPTLFLAQLSNLLAGNISIVH
KVTGSSRTFMGEEGCGLSAFQIAVARIRSGQSTHVLVGSSYNAQGYDMLLAHELGGLLSRSGWSPVWDRKNCLGGGIITG
SGGIFLVLENGKHAKKRNARAYAEISQIITDQTDRTNIPLEKSIATLLKTVGAKNSLVISAASGFHEVTKAEQNALEAND
MFYRGITTLFGYMREAQFPLALALAALSIEKKRCFPAFSAHEKPFPKEIREAFVTTIGIKRAEGIAQLTAV

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 42371; Mature: 42371

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDQTVFITGIGLITSLGEGVEHHWDILNNTTLTPNLDCTTFSPYTIHKLPEINWGLQIP
CCCCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCEECC
KRSDQRQMGTWQRLGTYAAGLALDDAGIKNNEQLTSTMDMIVAAGGGERDIDVDTQILSK
CCCCHHHHHHHHHHHHHHHCEEECCCCCCCCHHHHHHHHHHEECCCCCCCCCHHHHHHHH
ARIGADHASMLNSILSTELRPTLFLAQLSNLLAGNISIVHKVTGSSRTFMGEEGCGLSAF
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEECCCCCEECCCCCCCHHHH
QIAVARIRSGQSTHVLVGSSYNAQGYDMLLAHELGGLLSRSGWSPVWDRKNCLGGGIITG
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEC
SGGIFLVLENGKHAKKRNARAYAEISQIITDQTDRTNIPLEKSIATLLKTVGAKNSLVIS
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEE
AASGFHEVTKAEQNALEANDMFYRGITTLFGYMREAQFPLALALAALSIEKKRCFPAFSA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
HEKPFPKEIREAFVTTIGIKRAEGIAQLTAV
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MHDQTVFITGIGLITSLGEGVEHHWDILNNTTLTPNLDCTTFSPYTIHKLPEINWGLQIP
CCCCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCEECC
KRSDQRQMGTWQRLGTYAAGLALDDAGIKNNEQLTSTMDMIVAAGGGERDIDVDTQILSK
CCCCHHHHHHHHHHHHHHHCEEECCCCCCCCHHHHHHHHHHEECCCCCCCCCHHHHHHHH
ARIGADHASMLNSILSTELRPTLFLAQLSNLLAGNISIVHKVTGSSRTFMGEEGCGLSAF
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEECCCCCEECCCCCCCHHHH
QIAVARIRSGQSTHVLVGSSYNAQGYDMLLAHELGGLLSRSGWSPVWDRKNCLGGGIITG
HHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEC
SGGIFLVLENGKHAKKRNARAYAEISQIITDQTDRTNIPLEKSIATLLKTVGAKNSLVIS
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEE
AASGFHEVTKAEQNALEANDMFYRGITTLFGYMREAQFPLALALAALSIEKKRCFPAFSA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
HEKPFPKEIREAFVTTIGIKRAEGIAQLTAV
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA