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The map label for this gene is kdsB

Identifier: 49475048

GI number: 49475048

Start: 312626

End: 313357

Strand: Reverse

Name: kdsB

Synonym: BH02360

Alternate gene names: 49475048

Gene position: 313357-312626 (Counterclockwise)

Preceding gene: 49475053

Following gene: 49475047

Centisome position: 16.23

GC content: 41.94

Gene sequence:

>732_bases
ATGGCTCTTGAACCAATTATTCTTATTCCCGCTCGTATAGGCTCAACCCGTCTTCCTCAAAAAGCTCTGGCAGAGATTGC
TGGAAAGCCAATGATTGTTCATGTTGCTGAACAGGCAAAAAAAGCCGCATTCGGGCGTATTATCGTTGCAACAGATCATA
ACAATATCGCCAAAGTCGTTACCGCTTATGGACATGAATGTATCATAACATGTCGTGATCATAAATCTGGATCTGATCGT
ATTTATGAAGCTTTAACCCATATTGATCCTGAACGACGCTACAATGTCATTTTGAATGTACAAGGTGACTTGCCAACGAT
AACGCCCCATGAAATCATCAGTGCTTTACGCCCTTTAGAAAATAGCTTAACTGATATTGCAACTTTGGGTGCAAAAATCG
TCGAAGAAAATGAAAAAACAGATCCGAATATTGTCAAAATTATTGGTACACCGCTTTCTCACAATCGCTTTCGTGCTCTT
TATTTTACCCGCGCGACAGCGCCTTATGGAGATGGTCCCCTTTACCATCATATTGGAATATATGCCTATCGACGCGAAGC
GCTCGAGAAATTTGTAGCGCTTAAACCCTCTCCCCTCGAGCAACGTGAAAAACTTGAACAATTACGCGCACTAGAGCATA
ATATGCGTATCGATGTAGAGATAGTCGATACAATTCCCTTAGGGGTCGATACACAACGTGATCTTGAAAGGGTACGCAAG
ATTTTAGCATGA

Upstream 100 bases:

>100_bases
TCAAACATTTATATTGTCATTCCCGCTTTTAGTTTAAGCTTTTTCCATATAATACACAACATTATAAACACATCATACAC
ACGATATTTGGAATTTTGCA

Downstream 100 bases:

>100_bases
AGATACTAAAAAAAACCAATAAAATCTCATTCCAAGGAGAATATGGCGCTAATTCCCATATCGCCTGTACTAATATGTTT
CCCAATATGGATGCTCTACC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MALEPIILIPARIGSTRLPQKALAEIAGKPMIVHVAEQAKKAAFGRIIVATDHNNIAKVVTAYGHECIITCRDHKSGSDR
IYEALTHIDPERRYNVILNVQGDLPTITPHEIISALRPLENSLTDIATLGAKIVEENEKTDPNIVKIIGTPLSHNRFRAL
YFTRATAPYGDGPLYHHIGIYAYRREALEKFVALKPSPLEQREKLEQLRALEHNMRIDVEIVDTIPLGVDTQRDLERVRK
ILA

Sequences:

>Translated_243_residues
MALEPIILIPARIGSTRLPQKALAEIAGKPMIVHVAEQAKKAAFGRIIVATDHNNIAKVVTAYGHECIITCRDHKSGSDR
IYEALTHIDPERRYNVILNVQGDLPTITPHEIISALRPLENSLTDIATLGAKIVEENEKTDPNIVKIIGTPLSHNRFRAL
YFTRATAPYGDGPLYHHIGIYAYRREALEKFVALKPSPLEQREKLEQLRALEHNMRIDVEIVDTIPLGVDTQRDLERVRK
ILA
>Mature_242_residues
ALEPIILIPARIGSTRLPQKALAEIAGKPMIVHVAEQAKKAAFGRIIVATDHNNIAKVVTAYGHECIITCRDHKSGSDRI
YEALTHIDPERRYNVILNVQGDLPTITPHEIISALRPLENSLTDIATLGAKIVEENEKTDPNIVKIIGTPLSHNRFRALY
FTRATAPYGDGPLYHHIGIYAYRREALEKFVALKPSPLEQREKLEQLRALEHNMRIDVEIVDTIPLGVDTQRDLERVRKI
LA

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=247, Percent_Identity=42.5101214574899, Blast_Score=168, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_BARHE (Q6G4U6)

Other databases:

- EMBL:   BX897699
- RefSeq:   YP_033089.1
- HSSP:   P04951
- ProteinModelPortal:   Q6G4U6
- SMR:   Q6G4U6
- GeneID:   2865568
- GenomeReviews:   BX897699_GR
- KEGG:   bhe:BH02360
- NMPDR:   fig|283166.1.peg.217
- HOGENOM:   HBG637773
- OMA:   IIPARLK
- PhylomeDB:   Q6G4U6
- ProtClustDB:   PRK05450
- BioCyc:   BHEN283166:BH02360-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 27280; Mature: 27149

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALEPIILIPARIGSTRLPQKALAEIAGKPMIVHVAEQAKKAAFGRIIVATDHNNIAKVV
CCCCCEEEEECCCCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHCEEEEEECCCCHHHHH
TAYGHECIITCRDHKSGSDRIYEALTHIDPERRYNVILNVQGDLPTITPHEIISALRPLE
HHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
NSLTDIATLGAKIVEENEKTDPNIVKIIGTPLSHNRFRALYFTRATAPYGDGPLYHHIGI
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHH
YAYRREALEKFVALKPSPLEQREKLEQLRALEHNMRIDVEIVDTIPLGVDTQRDLERVRK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCHHHHHHHHH
ILA
HHC
>Mature Secondary Structure 
ALEPIILIPARIGSTRLPQKALAEIAGKPMIVHVAEQAKKAAFGRIIVATDHNNIAKVV
CCCCEEEEECCCCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHCEEEEEECCCCHHHHH
TAYGHECIITCRDHKSGSDRIYEALTHIDPERRYNVILNVQGDLPTITPHEIISALRPLE
HHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
NSLTDIATLGAKIVEENEKTDPNIVKIIGTPLSHNRFRALYFTRATAPYGDGPLYHHIGI
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHH
YAYRREALEKFVALKPSPLEQREKLEQLRALEHNMRIDVEIVDTIPLGVDTQRDLERVRK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCHHHHHHHHH
ILA
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA