Click here to switch to the map view.

The map label for this gene is pheA [H]

Identifier: 49475047

GI number: 49475047

Start: 311766

End: 312629

Strand: Reverse

Name: pheA [H]

Synonym: BH02350

Alternate gene names: 49475047

Gene position: 312629-311766 (Counterclockwise)

Preceding gene: 49475048

Following gene: 49475045

Centisome position: 16.19

GC content: 39.24

Gene sequence:

>864_bases
ATGAAGATACTAAAAAAAACCAATAAAATCTCATTCCAAGGAGAATATGGCGCTAATTCCCATATCGCCTGTACTAATAT
GTTTCCCAATATGGATGCTCTACCCTCAACAACTTTTGAAGACGCGCTTAACTTAGTGGAAAATGGACAAGCTGATCTTG
CTATGATTCCTATTGAAAATACTCTTGCTGGCCGCGTTGCCGATATTCATCACCTTTTACCACAATCATCTCTCTATATT
ATTGATGAATATTTTTTGCCTATTCATTTTCAATTAATGGTTTTACCCGGCGTTACACATAAAGAAATTGAAACCGTTCA
TAGTCATGCGCATGCCCTTGCACAATGCCGTAAAATCATTCGTAATAATGGCTGGCAACCTGTAACTTCTGCTGATACAG
CTGGAGCTGCAAAATTTATTAAAAAAAACGGAAAGCGTTCACAAGCAGCCTTAGCACCTCTGATCGCAGCGGAACTCTAT
GGACTTGATATTCTTGAAAAAAATGTTGAAGATAGCCCTCATAATATTACCCGTTTTGTCATCCTTTCACGTTCTCAACG
GCACGTGCCCAAACCCCAAAATGGCGAAAAAATTATCACTAGCCTTCTTTTTCGAGTCCGCAATGTCCCAGCTGCTCTTT
ATAAAGCTATGGGAGGATTTGCCACAAACGGTATCAATATGACAAAATTAGAAAGCTACCAAATTGGTGGCAATTTCAAT
GCAACACAATTTTTTGTTGATATCGAAGGGCATCCTGAAGACCCCATGATGCAACTTGCCTTAGATGAGCTGTCCTTCTT
TTCTGCTGAATTGCGCATTATTGGCATTTATCCTGCTAAAAATGGTCGAAGATCACACATATAA

Upstream 100 bases:

>100_bases
CACTAGAGCATAATATGCGTATCGATGTAGAGATAGTCGATACAATTCCCTTAGGGGTCGATACACAACGTGATCTTGAA
AGGGTACGCAAGATTTTAGC

Downstream 100 bases:

>100_bases
AAATTAATTAAATTGTACATTTCTCGTGGAGATTGAAGGGCATACTAAAGATCTCACGATACAACGCCCCTTGAAAAACA
GCGGCTTTCTTTTCTGCTAA

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKILKKTNKISFQGEYGANSHIACTNMFPNMDALPSTTFEDALNLVENGQADLAMIPIENTLAGRVADIHHLLPQSSLYI
IDEYFLPIHFQLMVLPGVTHKEIETVHSHAHALAQCRKIIRNNGWQPVTSADTAGAAKFIKKNGKRSQAALAPLIAAELY
GLDILEKNVEDSPHNITRFVILSRSQRHVPKPQNGEKIITSLLFRVRNVPAALYKAMGGFATNGINMTKLESYQIGGNFN
ATQFFVDIEGHPEDPMMQLALDELSFFSAELRIIGIYPAKNGRRSHI

Sequences:

>Translated_287_residues
MKILKKTNKISFQGEYGANSHIACTNMFPNMDALPSTTFEDALNLVENGQADLAMIPIENTLAGRVADIHHLLPQSSLYI
IDEYFLPIHFQLMVLPGVTHKEIETVHSHAHALAQCRKIIRNNGWQPVTSADTAGAAKFIKKNGKRSQAALAPLIAAELY
GLDILEKNVEDSPHNITRFVILSRSQRHVPKPQNGEKIITSLLFRVRNVPAALYKAMGGFATNGINMTKLESYQIGGNFN
ATQFFVDIEGHPEDPMMQLALDELSFFSAELRIIGIYPAKNGRRSHI
>Mature_287_residues
MKILKKTNKISFQGEYGANSHIACTNMFPNMDALPSTTFEDALNLVENGQADLAMIPIENTLAGRVADIHHLLPQSSLYI
IDEYFLPIHFQLMVLPGVTHKEIETVHSHAHALAQCRKIIRNNGWQPVTSADTAGAAKFIKKNGKRSQAALAPLIAAELY
GLDILEKNVEDSPHNITRFVILSRSQRHVPKPQNGEKIITSLLFRVRNVPAALYKAMGGFATNGINMTKLESYQIGGNFN
ATQFFVDIEGHPEDPMMQLALDELSFFSAELRIIGIYPAKNGRRSHI

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=285, Percent_Identity=32.9824561403509, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31872; Mature: 31872

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILKKTNKISFQGEYGANSHIACTNMFPNMDALPSTTFEDALNLVENGQADLAMIPIEN
CCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCC
TLAGRVADIHHLLPQSSLYIIDEYFLPIHFQLMVLPGVTHKEIETVHSHAHALAQCRKII
HHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RNNGWQPVTSADTAGAAKFIKKNGKRSQAALAPLIAAELYGLDILEKNVEDSPHNITRFV
HCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
ILSRSQRHVPKPQNGEKIITSLLFRVRNVPAALYKAMGGFATNGINMTKLESYQIGGNFN
EEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEEEEECCCCC
ATQFFVDIEGHPEDPMMQLALDELSFFSAELRIIGIYPAKNGRRSHI
CEEEEEEECCCCCCHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MKILKKTNKISFQGEYGANSHIACTNMFPNMDALPSTTFEDALNLVENGQADLAMIPIEN
CCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCC
TLAGRVADIHHLLPQSSLYIIDEYFLPIHFQLMVLPGVTHKEIETVHSHAHALAQCRKII
HHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RNNGWQPVTSADTAGAAKFIKKNGKRSQAALAPLIAAELYGLDILEKNVEDSPHNITRFV
HCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
ILSRSQRHVPKPQNGEKIITSLLFRVRNVPAALYKAMGGFATNGINMTKLESYQIGGNFN
EEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEEEEECCCCC
ATQFFVDIEGHPEDPMMQLALDELSFFSAELRIIGIYPAKNGRRSHI
CEEEEEEECCCCCCHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512561; 1444388 [H]