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The map label for this gene is dnaX [H]

Identifier: 49475044

GI number: 49475044

Start: 307669

End: 309609

Strand: Reverse

Name: dnaX [H]

Synonym: BH02320

Alternate gene names: 49475044

Gene position: 309609-307669 (Counterclockwise)

Preceding gene: 49475045

Following gene: 49475043

Centisome position: 16.03

GC content: 39.41

Gene sequence:

>1941_bases
ATGAAAAATATGCCGGTAGAAACAACCTATCGCGTTCTTGCTCGTAAATATCGACCTCAAAATTTCTCCGACCTCATTGG
TCAAGAAGCGATGGTGCGCACTCTTACTAACGCCTTTGAAACAGGACGCATAGCACAAGCATGGATGCTCACGGGAATTC
GTGGAGTGGGAAAAACCACAACAGCACGTATTTTAGCACGTGCACTCAACTATAAAACAAAAGATATTGACCAACCAACA
ACCGTATTGAATACACTTGGTGAACATTGCACGCAAATCATTGAAGGACGCCATATTGATGTTATCGAAATGGACGCAGC
TTCACATACGGGTATTGATGATATTCGTGAAATTATTGAACAAATACGTTATCGTCCTGTTTCTGCGCGCTATAAGGTTT
ATATTATTGATGAAGTACACATGCTCTCAACACAGGCATTTAACGGCTTATTAAAAACACTTGAAGAGCCACCACCACAT
GTAAAATTTATTTTTGCAACAACAGAGATTCGTAAAGTTCCTATTACGATCCTTTCACGTTGCCAACGTTTTGACCTACG
GCGTATTGAATCGGCAGTTTTGAGTGCACATCTACGCCAAATTGCTCAACATGAAAATGTGGAAGTGGAAGATCAAGCGC
TCTCCATGATTGCACGCGCTGCAGAAGGCTCCGCACGAGATGCACTCTCTATTTTTGATCAAGCAATTGCTCATAGCAAT
GGCAAAATCAGCGCTGTTACAGTGCGAGCAATGCTCGGCTTAGCTGATCAAGCTCGTATTATTGATCTGTTCGAATTCCT
CATGAAGGGGAATGTTGTCAATGCACTCCATGAATTACGTAGCCAATATGATGCCGGTGCTGATCCCCTTACCATATTGA
CAGAATTAGCCGATTTCAATCATCTGGTCACACGTTTGCGTTTCACACCAGAGATATTGGAAGATCTCTCACTTACTGAA
GACGAGCGTTTGAGAAGCTTAGATTTTTCAAAAAAACTTTCCGTTCCTGTTTTGTCTCGAAACTGGCAAATGTTACTGAA
AGGTTTACAGGAAGTGAATCAAACCGCGCGTCCACTTCAAGCTGCTGAAATGTTATTAATTCGCCTTGCTCATGTTACAG
ATCTGCCAACTCTTGATGAAGCTTTAAAAAAGCTTATGCAAGAAACAACACCTCTTACAATCGTTTCCAATTCTTCTCAT
CAAGAGTCCACAAGTACGAATAATACAACAAAAATAGAAGCTGCAAACGCCTATTCTTCTTTACAGGTTGCAAACCCGTC
GTCACACCAGCCAGATTGCAAAACATCCGTGACAAACCACTTAAATGATTGCTTACAATCGGAAAATTTACTCAAATTTC
AAAACCTCGAAAGCTCTCACTCTCCTGAAGTCACAGAAATTCTTGAAACTTCTCAATCTGTTACCAATCCTCAAAATATT
ACAAATTTACCGCATCCCTCCACACACACAACAAAGCAAGCCACTCAACCAAAAGCTATAGTTATTGATTCTTTGCACGA
TATTGTTAAATTAGCTGAACAGCATGATGAGATCACTTTTAAACTTCTCATTACAGAATTTGTTCACCCTGTTTCTTTTG
AACCAGGACATATCATTTTGAGGATTGCTGAAAATGCTCCACATTCACTTAAGAATGACATAAAAAAAATGCTGTCTCAA
TGGACTGAAAAACGGTTGACTATAACCTTTGTTAATGAAGGAGGAGGACCAACCCTACAAGAAGAAAGTATGGCTATCCA
AAAAACTCTTTTTTCCAATGCAGAAGCAGATCCTGATATAGCGAAAATCCTCTATCATTTTCCAGAAGCAAAAATTGTCG
ATATTCGCCTAAATAAACAAGAAAACAACCTTGATTTACTCCCTAATACCTTTAAAAATGCCGATACCTTTAAAAATGAA
AATGATATCGATGATGAATAA

Upstream 100 bases:

>100_bases
TATTGATTGAGAAAAAATCCTTTTATATTAGAGTACAGTATTAGCTTGTCTCGCATGTTATCGAAAATGTCCTACAAACG
CTTTAAAGTTGGAATCATTG

Downstream 100 bases:

>100_bases
GGATACCTATTCCTATGCGTGATATGATGAACATGATGAAAAAAGCCAAAGAAATGCAAGAAAAAATGCAGAAAATTCAA
GAGGAAATGGCAAATCTGCA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MKNMPVETTYRVLARKYRPQNFSDLIGQEAMVRTLTNAFETGRIAQAWMLTGIRGVGKTTTARILARALNYKTKDIDQPT
TVLNTLGEHCTQIIEGRHIDVIEMDAASHTGIDDIREIIEQIRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPPH
VKFIFATTEIRKVPITILSRCQRFDLRRIESAVLSAHLRQIAQHENVEVEDQALSMIARAAEGSARDALSIFDQAIAHSN
GKISAVTVRAMLGLADQARIIDLFEFLMKGNVVNALHELRSQYDAGADPLTILTELADFNHLVTRLRFTPEILEDLSLTE
DERLRSLDFSKKLSVPVLSRNWQMLLKGLQEVNQTARPLQAAEMLLIRLAHVTDLPTLDEALKKLMQETTPLTIVSNSSH
QESTSTNNTTKIEAANAYSSLQVANPSSHQPDCKTSVTNHLNDCLQSENLLKFQNLESSHSPEVTEILETSQSVTNPQNI
TNLPHPSTHTTKQATQPKAIVIDSLHDIVKLAEQHDEITFKLLITEFVHPVSFEPGHIILRIAENAPHSLKNDIKKMLSQ
WTEKRLTITFVNEGGGPTLQEESMAIQKTLFSNAEADPDIAKILYHFPEAKIVDIRLNKQENNLDLLPNTFKNADTFKNE
NDIDDE

Sequences:

>Translated_646_residues
MKNMPVETTYRVLARKYRPQNFSDLIGQEAMVRTLTNAFETGRIAQAWMLTGIRGVGKTTTARILARALNYKTKDIDQPT
TVLNTLGEHCTQIIEGRHIDVIEMDAASHTGIDDIREIIEQIRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPPH
VKFIFATTEIRKVPITILSRCQRFDLRRIESAVLSAHLRQIAQHENVEVEDQALSMIARAAEGSARDALSIFDQAIAHSN
GKISAVTVRAMLGLADQARIIDLFEFLMKGNVVNALHELRSQYDAGADPLTILTELADFNHLVTRLRFTPEILEDLSLTE
DERLRSLDFSKKLSVPVLSRNWQMLLKGLQEVNQTARPLQAAEMLLIRLAHVTDLPTLDEALKKLMQETTPLTIVSNSSH
QESTSTNNTTKIEAANAYSSLQVANPSSHQPDCKTSVTNHLNDCLQSENLLKFQNLESSHSPEVTEILETSQSVTNPQNI
TNLPHPSTHTTKQATQPKAIVIDSLHDIVKLAEQHDEITFKLLITEFVHPVSFEPGHIILRIAENAPHSLKNDIKKMLSQ
WTEKRLTITFVNEGGGPTLQEESMAIQKTLFSNAEADPDIAKILYHFPEAKIVDIRLNKQENNLDLLPNTFKNADTFKNE
NDIDDE
>Mature_646_residues
MKNMPVETTYRVLARKYRPQNFSDLIGQEAMVRTLTNAFETGRIAQAWMLTGIRGVGKTTTARILARALNYKTKDIDQPT
TVLNTLGEHCTQIIEGRHIDVIEMDAASHTGIDDIREIIEQIRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPPH
VKFIFATTEIRKVPITILSRCQRFDLRRIESAVLSAHLRQIAQHENVEVEDQALSMIARAAEGSARDALSIFDQAIAHSN
GKISAVTVRAMLGLADQARIIDLFEFLMKGNVVNALHELRSQYDAGADPLTILTELADFNHLVTRLRFTPEILEDLSLTE
DERLRSLDFSKKLSVPVLSRNWQMLLKGLQEVNQTARPLQAAEMLLIRLAHVTDLPTLDEALKKLMQETTPLTIVSNSSH
QESTSTNNTTKIEAANAYSSLQVANPSSHQPDCKTSVTNHLNDCLQSENLLKFQNLESSHSPEVTEILETSQSVTNPQNI
TNLPHPSTHTTKQATQPKAIVIDSLHDIVKLAEQHDEITFKLLITEFVHPVSFEPGHIILRIAENAPHSLKNDIKKMLSQ
WTEKRLTITFVNEGGGPTLQEESMAIQKTLFSNAEADPDIAKILYHFPEAKIVDIRLNKQENNLDLLPNTFKNADTFKNE
NDIDDE

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=306, Percent_Identity=25.1633986928105, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI194306571, Length=296, Percent_Identity=24.6621621621622, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI194306567, Length=296, Percent_Identity=24.6621621621622, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4506491, Length=266, Percent_Identity=23.3082706766917, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI31881687, Length=266, Percent_Identity=23.3082706766917, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI1786676, Length=361, Percent_Identity=40.1662049861496, Blast_Score=275, Evalue=8e-75,
Organism=Caenorhabditis elegans, GI17541988, Length=218, Percent_Identity=27.5229357798165, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71986063, Length=296, Percent_Identity=22.2972972972973, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17554730, Length=222, Percent_Identity=22.972972972973, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324478, Length=283, Percent_Identity=24.0282685512367, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322528, Length=301, Percent_Identity=21.5946843853821, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324039, Length=224, Percent_Identity=22.3214285714286, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17647857, Length=236, Percent_Identity=28.8135593220339, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859927, Length=269, Percent_Identity=24.1635687732342, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 72693; Mature: 72693

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNMPVETTYRVLARKYRPQNFSDLIGQEAMVRTLTNAFETGRIAQAWMLTGIRGVGKTT
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHH
TARILARALNYKTKDIDQPTTVLNTLGEHCTQIIEGRHIDVIEMDAASHTGIDDIREIIE
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
QIRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPPHVKFIFATTEIRKVPITILSR
HHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHH
CQRFDLRRIESAVLSAHLRQIAQHENVEVEDQALSMIARAAEGSARDALSIFDQAIAHSN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
GKISAVTVRAMLGLADQARIIDLFEFLMKGNVVNALHELRSQYDAGADPLTILTELADFN
CCEEHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
HLVTRLRFTPEILEDLSLTEDERLRSLDFSKKLSVPVLSRNWQMLLKGLQEVNQTARPLQ
HHHHHHHCCHHHHHHCCCCHHHHHHHCCCHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHH
AAEMLLIRLAHVTDLPTLDEALKKLMQETTPLTIVSNSSHQESTSTNNTTKIEAANAYSS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCCCCC
LQVANPSSHQPDCKTSVTNHLNDCLQSENLLKFQNLESSHSPEVTEILETSQSVTNPQNI
EEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCHHC
TNLPHPSTHTTKQATQPKAIVIDSLHDIVKLAEQHDEITFKLLITEFVHPVSFEPGHIIL
CCCCCCCCCCCHHCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEE
RIAENAPHSLKNDIKKMLSQWTEKRLTITFVNEGGGPTLQEESMAIQKTLFSNAEADPDI
EEECCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHH
AKILYHFPEAKIVDIRLNKQENNLDLLPNTFKNADTFKNENDIDDE
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure
MKNMPVETTYRVLARKYRPQNFSDLIGQEAMVRTLTNAFETGRIAQAWMLTGIRGVGKTT
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHH
TARILARALNYKTKDIDQPTTVLNTLGEHCTQIIEGRHIDVIEMDAASHTGIDDIREIIE
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
QIRYRPVSARYKVYIIDEVHMLSTQAFNGLLKTLEEPPPHVKFIFATTEIRKVPITILSR
HHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHH
CQRFDLRRIESAVLSAHLRQIAQHENVEVEDQALSMIARAAEGSARDALSIFDQAIAHSN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
GKISAVTVRAMLGLADQARIIDLFEFLMKGNVVNALHELRSQYDAGADPLTILTELADFN
CCEEHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
HLVTRLRFTPEILEDLSLTEDERLRSLDFSKKLSVPVLSRNWQMLLKGLQEVNQTARPLQ
HHHHHHHCCHHHHHHCCCCHHHHHHHCCCHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHH
AAEMLLIRLAHVTDLPTLDEALKKLMQETTPLTIVSNSSHQESTSTNNTTKIEAANAYSS
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCCCCC
LQVANPSSHQPDCKTSVTNHLNDCLQSENLLKFQNLESSHSPEVTEILETSQSVTNPQNI
EEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCHHC
TNLPHPSTHTTKQATQPKAIVIDSLHDIVKLAEQHDEITFKLLITEFVHPVSFEPGHIIL
CCCCCCCCCCCHHCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEE
RIAENAPHSLKNDIKKMLSQWTEKRLTITFVNEGGGPTLQEESMAIQKTLFSNAEADPDI
EEECCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHH
AKILYHFPEAKIVDIRLNKQENNLDLLPNTFKNADTFKNENDIDDE
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]