Click here to switch to the map view.

The map label for this gene is coaA [H]

Identifier: 49475017

GI number: 49475017

Start: 277715

End: 278713

Strand: Reverse

Name: coaA [H]

Synonym: BH02050

Alternate gene names: 49475017

Gene position: 278713-277715 (Counterclockwise)

Preceding gene: 49475018

Following gene: 49475016

Centisome position: 14.43

GC content: 34.93

Gene sequence:

>999_bases
ATGATTGATACAATTCTCCCAAAAATTAATCAGGAAGATAATTTAGTCAAATCGATTTCCGATCGATATTCGCCCTATCG
TGTCTTTACTGCACAAGAATGGTCTCAATTTCGTGCAGATACACCGCTTACTTTGACCTTTGATGAAATCAAACGTTTAC
GCTCAATTGATGATCCAATTGATCTTGAAGAAGTGCAACGTATTTATCTTTCTTTATCACGTTTGTTATCATGCCATGTT
GAAGCTGTACAAGAACTTTTTCACAAGCGTCAACAATTTTTATATCAAGAAGGAACGAGAAAAACTCCTTTTATCATTGG
AATTGCTGGCTCTGTTGCAGTAGGAAAATCAACTACCGCTCGTATTCTACAAGAACTTTTGAAACGTTGGACTTCCAGTC
TTAAAGTTGATTTGATTACAACGGATGGTTTTCTCTATCCTAACGCTGTTTTACAGCAAAAAAATCGTATGAATCGTAAA
GGATTTCCAGATTCCTATGATATTAAGAAATTACTGTGCTTTCTTTCTGCTATAAAAGCCGGTATTGGTAATGTACGTGC
CCCACTTTATTCGCATATGATTTATGATGTTTTAGAAAATCAAACAGTTACCATTGATCGTCCCGATATCTTAATTGTTG
AAGGGATTAACGTGTTACAAGTCAATGACCTCCCTAAAGACGGTAAAATTATTCCTTTTGTTTCAGATTTTTTTGATTTT
TCAATCTATGTAGATGCTGAAACAGAAGTCATTCGACACTGGTATTTGGAACGTTTTAAACGTTTGCGTAAAACAGCTTT
TCAAAATCCTAAGTCCTATTTTCATCGTTATGCACTCATGCATGAAGAAGAGTCCTTAAAAATCGCTGAAAATATCTGGC
AAACAATTAATTTGAAAAATTTACAAGAAAATATATTGCCAACACGACCACGGTCTAATCTCATTCTACGCAAGGGAAAA
AAACATTTGGTTGAATATGTGGCACTTCGACGACTATAG

Upstream 100 bases:

>100_bases
AAGAAGAAAACATGCAAAATAAAGTTCATTTAAATACAAAAGGGCCTGCCTGTCTATCCTTAATCAATTACTTCGGCAAA
AAAATTCTCGACTAATACAA

Downstream 100 bases:

>100_bases
ACTATAAAGGTTTCTAAATATGCATTTACATCACATTCATTTTACTTCAACACGTATTGATAATAGTTGTCCCATATTTT
TGGTAAACCAGAGAAGTCTG

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MIDTILPKINQEDNLVKSISDRYSPYRVFTAQEWSQFRADTPLTLTFDEIKRLRSIDDPIDLEEVQRIYLSLSRLLSCHV
EAVQELFHKRQQFLYQEGTRKTPFIIGIAGSVAVGKSTTARILQELLKRWTSSLKVDLITTDGFLYPNAVLQQKNRMNRK
GFPDSYDIKKLLCFLSAIKAGIGNVRAPLYSHMIYDVLENQTVTIDRPDILIVEGINVLQVNDLPKDGKIIPFVSDFFDF
SIYVDAETEVIRHWYLERFKRLRKTAFQNPKSYFHRYALMHEEESLKIAENIWQTINLKNLQENILPTRPRSNLILRKGK
KHLVEYVALRRL

Sequences:

>Translated_332_residues
MIDTILPKINQEDNLVKSISDRYSPYRVFTAQEWSQFRADTPLTLTFDEIKRLRSIDDPIDLEEVQRIYLSLSRLLSCHV
EAVQELFHKRQQFLYQEGTRKTPFIIGIAGSVAVGKSTTARILQELLKRWTSSLKVDLITTDGFLYPNAVLQQKNRMNRK
GFPDSYDIKKLLCFLSAIKAGIGNVRAPLYSHMIYDVLENQTVTIDRPDILIVEGINVLQVNDLPKDGKIIPFVSDFFDF
SIYVDAETEVIRHWYLERFKRLRKTAFQNPKSYFHRYALMHEEESLKIAENIWQTINLKNLQENILPTRPRSNLILRKGK
KHLVEYVALRRL
>Mature_332_residues
MIDTILPKINQEDNLVKSISDRYSPYRVFTAQEWSQFRADTPLTLTFDEIKRLRSIDDPIDLEEVQRIYLSLSRLLSCHV
EAVQELFHKRQQFLYQEGTRKTPFIIGIAGSVAVGKSTTARILQELLKRWTSSLKVDLITTDGFLYPNAVLQQKNRMNRK
GFPDSYDIKKLLCFLSAIKAGIGNVRAPLYSHMIYDVLENQTVTIDRPDILIVEGINVLQVNDLPKDGKIIPFVSDFFDF
SIYVDAETEVIRHWYLERFKRLRKTAFQNPKSYFHRYALMHEEESLKIAENIWQTINLKNLQENILPTRPRSNLILRKGK
KHLVEYVALRRL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=309, Percent_Identity=51.4563106796116, Blast_Score=317, Evalue=7e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 38834; Mature: 38834

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTILPKINQEDNLVKSISDRYSPYRVFTAQEWSQFRADTPLTLTFDEIKRLRSIDDPI
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCEEEHHHHHHHHCCCCCC
DLEEVQRIYLSLSRLLSCHVEAVQELFHKRQQFLYQEGTRKTPFIIGIAGSVAVGKSTTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
RILQELLKRWTSSLKVDLITTDGFLYPNAVLQQKNRMNRKGFPDSYDIKKLLCFLSAIKA
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
GIGNVRAPLYSHMIYDVLENQTVTIDRPDILIVEGINVLQVNDLPKDGKIIPFVSDFFDF
HCCCHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCEEEECCCCCCCCEECCHHHCCCE
SIYVDAETEVIRHWYLERFKRLRKTAFQNPKSYFHRYALMHEEESLKIAENIWQTINLKN
EEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHH
LQENILPTRPRSNLILRKGKKHLVEYVALRRL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDTILPKINQEDNLVKSISDRYSPYRVFTAQEWSQFRADTPLTLTFDEIKRLRSIDDPI
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCEEEHHHHHHHHCCCCCC
DLEEVQRIYLSLSRLLSCHVEAVQELFHKRQQFLYQEGTRKTPFIIGIAGSVAVGKSTTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
RILQELLKRWTSSLKVDLITTDGFLYPNAVLQQKNRMNRKGFPDSYDIKKLLCFLSAIKA
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
GIGNVRAPLYSHMIYDVLENQTVTIDRPDILIVEGINVLQVNDLPKDGKIIPFVSDFFDF
HCCCHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCEEEECCCCCCCCEECCHHHCCCE
SIYVDAETEVIRHWYLERFKRLRKTAFQNPKSYFHRYALMHEEESLKIAENIWQTINLKN
EEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHH
LQENILPTRPRSNLILRKGKKHLVEYVALRRL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA