The gene/protein map for NC_002945 is currently unavailable.
Definition Bartonella henselae str. Houston-1, complete genome.
Accession NC_005956
Length 1,931,047

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The map label for this gene is ccmA

Identifier: 49474933

GI number: 49474933

Start: 153961

End: 154587

Strand: Reverse

Name: ccmA

Synonym: BH01150

Alternate gene names: 49474933

Gene position: 154587-153961 (Counterclockwise)

Preceding gene: 49474945

Following gene: 49474932

Centisome position: 8.01

GC content: 40.35

Gene sequence:

>627_bases
ATGGTGTTATCGGGCAAAGATTTGACAGCTTACAGAAACGAAGATGTTCTGTTCCAAGGTCTTTCTTTTTGTTTATTCCC
ACAACAACTTATGACAATCACAGGACCAAATGGGATTGGGAAATCTACATTACTCAGAATCATTGCTGGGCTATTTAAAG
CTGCTGAAGGTCATGTAAGTCTTAAAGACCAGGAACAAATATATCCTGTAGCAACAGCATGTCATTATCTTGGACCTCAA
AATGCTATGAAACCTTTCTTATCGGTCATCGACAACTTGCAATTTTGGTCAGCATTTTATGGGCAACCTCTACACTCTCC
ACACGAAGTCCTTGCAGATATTGGTCTTTCTGATCTTGAACACGTACCCTTTAACGTTCTATCAACCGGGCAAAAAAGGC
GTATAGCTATTGCCCGCCTTTTACTATCTTACCGTCCTGTTTGGATTTTAGATGAACCAATATCGGGAATTGATAGCTAC
GCCCAAACTCTCCTTACCAATATTTTCCAGTACCATCTCAACCAAGGTGGTATGATTATCGCTGCAACCCATAGTCCTCT
CGGCATTCCAGAAAACCATAAAATTACCTTGGAAAAATTTTTACCTCCCCAGGAGAAAATACAATGA

Upstream 100 bases:

>100_bases
TATTTCTAGAACTATTCTAGGTACAATTATATAAAATAACGTGTTTTTTATCCTATAATGCAATAAAGATTATAGAAATA
AAGGTAAAATAGGTAATCAC

Downstream 100 bases:

>100_bases
AAGCACTGTTCTGGCGTGATCTTAAATTAACCTTAGCACCACAAGCTTCCTCGTTAAAAGGGCTTTTGTTTTTCATTGCT
ATTATTATGATAATCCCCTT

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MVLSGKDLTAYRNEDVLFQGLSFCLFPQQLMTITGPNGIGKSTLLRIIAGLFKAAEGHVSLKDQEQIYPVATACHYLGPQ
NAMKPFLSVIDNLQFWSAFYGQPLHSPHEVLADIGLSDLEHVPFNVLSTGQKRRIAIARLLLSYRPVWILDEPISGIDSY
AQTLLTNIFQYHLNQGGMIIAATHSPLGIPENHKITLEKFLPPQEKIQ

Sequences:

>Translated_208_residues
MVLSGKDLTAYRNEDVLFQGLSFCLFPQQLMTITGPNGIGKSTLLRIIAGLFKAAEGHVSLKDQEQIYPVATACHYLGPQ
NAMKPFLSVIDNLQFWSAFYGQPLHSPHEVLADIGLSDLEHVPFNVLSTGQKRRIAIARLLLSYRPVWILDEPISGIDSY
AQTLLTNIFQYHLNQGGMIIAATHSPLGIPENHKITLEKFLPPQEKIQ
>Mature_208_residues
MVLSGKDLTAYRNEDVLFQGLSFCLFPQQLMTITGPNGIGKSTLLRIIAGLFKAAEGHVSLKDQEQIYPVATACHYLGPQ
NAMKPFLSVIDNLQFWSAFYGQPLHSPHEVLADIGLSDLEHVPFNVLSTGQKRRIAIARLLLSYRPVWILDEPISGIDSY
AQTLLTNIFQYHLNQGGMIIAATHSPLGIPENHKITLEKFLPPQEKIQ

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI27436953, Length=162, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI153792144, Length=167, Percent_Identity=30.5389221556886, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI215820660, Length=182, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI20143975, Length=182, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI47078218, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI45446740, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI27477115, Length=161, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI27262624, Length=189, Percent_Identity=26.984126984127, Blast_Score=64, Evalue=7e-11,
Organism=Homo sapiens, GI27262626, Length=189, Percent_Identity=26.984126984127, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI87082064, Length=197, Percent_Identity=39.0862944162437, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790467, Length=190, Percent_Identity=29.4736842105263, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786563, Length=176, Percent_Identity=29.5454545454545, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787105, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081709, Length=161, Percent_Identity=26.7080745341615, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787712, Length=145, Percent_Identity=29.6551724137931, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI87082267, Length=145, Percent_Identity=28.9655172413793, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790544, Length=181, Percent_Identity=27.6243093922652, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787164, Length=176, Percent_Identity=29.5454545454545, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786253, Length=166, Percent_Identity=29.5180722891566, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1786803, Length=192, Percent_Identity=28.125, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787370, Length=146, Percent_Identity=30.8219178082192, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=174, Percent_Identity=28.735632183908, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081782, Length=194, Percent_Identity=25.7731958762887, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28574744, Length=184, Percent_Identity=30.4347826086957, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574533, Length=173, Percent_Identity=31.2138728323699, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI85724864, Length=183, Percent_Identity=29.5081967213115, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24580555, Length=183, Percent_Identity=29.5081967213115, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI85816269, Length=183, Percent_Identity=29.5081967213115, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24580553, Length=183, Percent_Identity=29.5081967213115, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCMA_BARHE (Q6G529)

Other databases:

- EMBL:   BX897699
- RefSeq:   YP_032974.1
- ProteinModelPortal:   Q6G529
- SMR:   Q6G529
- GeneID:   2865407
- GenomeReviews:   BX897699_GR
- KEGG:   bhe:BH01150
- NMPDR:   fig|283166.1.peg.102
- HOGENOM:   HBG758042
- OMA:   ARLWHND
- PhylomeDB:   Q6G529
- ProtClustDB:   PRK13539
- BioCyc:   BHEN283166:BH01150-MONOMER
- BRENDA:   3.6.3.41
- HAMAP:   MF_01707
- InterPro:   IPR003439
- InterPro:   IPR005895
- InterPro:   IPR003593
- PANTHER:   PTHR19222:SF5
- SMART:   SM00382
- TIGRFAMs:   TIGR01189

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.41

Molecular weight: Translated: 23164; Mature: 23164

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51243 CCMA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MVLSGKDLTAYRNEDVLFQGLSFCLFPQQLMTITGPNGIGKSTLLRIIAGLFKAAEGHVS
CCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCC
LKDQEQIYPVATACHYLGPQNAMKPFLSVIDNLQFWSAFYGQPLHSPHEVLADIGLSDLE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHH
HVPFNVLSTGQKRRIAIARLLLSYRPVWILDEPISGIDSYAQTLLTNIFQYHLNQGGMII
HCCHHHHCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEE
AATHSPLGIPENHKITLEKFLPPQEKIQ
EECCCCCCCCCCCCEEHHHCCCCHHHCC
>Mature Secondary Structure
MVLSGKDLTAYRNEDVLFQGLSFCLFPQQLMTITGPNGIGKSTLLRIIAGLFKAAEGHVS
CCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCC
LKDQEQIYPVATACHYLGPQNAMKPFLSVIDNLQFWSAFYGQPLHSPHEVLADIGLSDLE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHH
HVPFNVLSTGQKRRIAIARLLLSYRPVWILDEPISGIDSYAQTLLTNIFQYHLNQGGMII
HCCHHHHCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEE
AATHSPLGIPENHKITLEKFLPPQEKIQ
EECCCCCCCCCCCCEEHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA