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The map label for this gene is accD [H]

Identifier: 49474862

GI number: 49474862

Start: 45697

End: 46617

Strand: Reverse

Name: accD [H]

Synonym: BH00340

Alternate gene names: 49474862

Gene position: 46617-45697 (Counterclockwise)

Preceding gene: 49474863

Following gene: 49474861

Centisome position: 2.41

GC content: 40.5

Gene sequence:

>921_bases
ATGAACTGGATTACAAATTATGTTCGTCCTAAAATCAATTCCATACTGGGACGCCGTGAAATTCCAGAAAATCTGTGGAT
CAAAGATCCTACCAGTGGTGAGATGGTCTTCCATAAAGATCTAGAAGTTAATCAATATGTAATCCCTAGTTCTGGTTATC
ACATGCGCATCAGCGCCAAAAACCGTCTTACACATTTTTTTGATGATGGTGTTTATACACCTCTTGAAAATCCAAAAGTT
GTAATAGACCCATTAAAGTTTCGCGATGAAAAACGTTATATTGACCGGCTAAAAGATTATCGTTCCAAACTTGGTATTGA
TGATAATATTTTAAGTGCACGCGGTACTATTGAAGGCTTACCGATTATAGCCACTGTTCAAGACTTCGCCTTTATGGGAG
GATCACTTGGTATGGCTTCAGGAGAAGCAATCATAAAAGCTTTTGATACTGCCATTGCCGAAAAATGCCCTTTAGTCCTT
TTTTCTGCTTCTGGCGGTGCACGCATGCAAGAAGGAACACTCTCCTTGATGCAAATGCCCCGTACAACTGTAGCTATCGA
AATGCTAAAAGAAGCAAAACTTCCCTACATCGTAGTTCTTACCAATCCAACCACCGGTGGAGTTACTGCTTCTTATGCCA
TGCTTGGCGATATTCACATTGCCGAACCTGGTGCTATGATTGGTTTTGCGGGACCACGTGTCATTCAACAAACCATACGC
GAAACCTTACCAGAAGGTTTTCAAAGTAGTGAATATCTGCTCAAACATGGCATGATTGATATGGTTGTATCACGTTTAGA
AATGAAAACTACCATTGCACGACTTTTACGTTTGATGATGAAATATCCCCCTGTTGTTAATCCTTCCAATACATCTTCGA
CCAATTCTCAGGCATCGCTTTCTAAAGCAGAAGCTGCTTAA

Upstream 100 bases:

>100_bases
TGGATTTGTTTATTTAGCTGGCAAAGCGAATTGACCATTCAATCTTATATTTTCTTGAATCGTGCAAAAAATGTATAACA
TTTAAAGAGAGGCTACAAAG

Downstream 100 bases:

>100_bases
ACTATGAAAAAAAACCACGTGCAAAGGATAATCGATGATTTACTGAAAAACTATCCTAAAAAATTTGATCTTTCTTTAGA
GCGTATCCTTCGTCTTTTAG

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNWITNYVRPKINSILGRREIPENLWIKDPTSGEMVFHKDLEVNQYVIPSSGYHMRISAKNRLTHFFDDGVYTPLENPKV
VIDPLKFRDEKRYIDRLKDYRSKLGIDDNILSARGTIEGLPIIATVQDFAFMGGSLGMASGEAIIKAFDTAIAEKCPLVL
FSASGGARMQEGTLSLMQMPRTTVAIEMLKEAKLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGAMIGFAGPRVIQQTIR
ETLPEGFQSSEYLLKHGMIDMVVSRLEMKTTIARLLRLMMKYPPVVNPSNTSSTNSQASLSKAEAA

Sequences:

>Translated_306_residues
MNWITNYVRPKINSILGRREIPENLWIKDPTSGEMVFHKDLEVNQYVIPSSGYHMRISAKNRLTHFFDDGVYTPLENPKV
VIDPLKFRDEKRYIDRLKDYRSKLGIDDNILSARGTIEGLPIIATVQDFAFMGGSLGMASGEAIIKAFDTAIAEKCPLVL
FSASGGARMQEGTLSLMQMPRTTVAIEMLKEAKLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGAMIGFAGPRVIQQTIR
ETLPEGFQSSEYLLKHGMIDMVVSRLEMKTTIARLLRLMMKYPPVVNPSNTSSTNSQASLSKAEAA
>Mature_306_residues
MNWITNYVRPKINSILGRREIPENLWIKDPTSGEMVFHKDLEVNQYVIPSSGYHMRISAKNRLTHFFDDGVYTPLENPKV
VIDPLKFRDEKRYIDRLKDYRSKLGIDDNILSARGTIEGLPIIATVQDFAFMGGSLGMASGEAIIKAFDTAIAEKCPLVL
FSASGGARMQEGTLSLMQMPRTTVAIEMLKEAKLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGAMIGFAGPRVIQQTIR
ETLPEGFQSSEYLLKHGMIDMVVSRLEMKTTIARLLRLMMKYPPVVNPSNTSSTNSQASLSKAEAA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=200, Percent_Identity=26.5, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1788655, Length=284, Percent_Identity=47.887323943662, Blast_Score=280, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 33904; Mature: 33904

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS01159 WW_DOMAIN_1 ; PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWITNYVRPKINSILGRREIPENLWIKDPTSGEMVFHKDLEVNQYVIPSSGYHMRISAK
CCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEECCCCCEEEECCCCCEEEEECC
NRLTHFFDDGVYTPLENPKVVIDPLKFRDEKRYIDRLKDYRSKLGIDDNILSARGTIEGL
CCHHHHHCCCCCCCCCCCEEEECCHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PIIATVQDFAFMGGSLGMASGEAIIKAFDTAIAEKCPLVLFSASGGARMQEGTLSLMQMP
EEEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHCC
RTTVAIEMLKEAKLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGAMIGFAGPRVIQQTIR
HHHHHHHHHHHCCCCEEEEEECCCCCCCEEHHHEEEEEEEECCCCEEECCCHHHHHHHHH
ETLPEGFQSSEYLLKHGMIDMVVSRLEMKTTIARLLRLMMKYPPVVNPSNTSSTNSQASL
HHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
SKAEAA
HHHCCC
>Mature Secondary Structure
MNWITNYVRPKINSILGRREIPENLWIKDPTSGEMVFHKDLEVNQYVIPSSGYHMRISAK
CCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEECCCCCEEEECCCCCEEEEECC
NRLTHFFDDGVYTPLENPKVVIDPLKFRDEKRYIDRLKDYRSKLGIDDNILSARGTIEGL
CCHHHHHCCCCCCCCCCCEEEECCHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PIIATVQDFAFMGGSLGMASGEAIIKAFDTAIAEKCPLVLFSASGGARMQEGTLSLMQMP
EEEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHCC
RTTVAIEMLKEAKLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGAMIGFAGPRVIQQTIR
HHHHHHHHHHHCCCCEEEEEECCCCCCCEEHHHEEEEEEEECCCCEEECCCHHHHHHHHH
ETLPEGFQSSEYLLKHGMIDMVVSRLEMKTTIARLLRLMMKYPPVVNPSNTSSTNSQASL
HHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
SKAEAA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA